These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
342 related articles for article (PubMed ID: 6389376)
1. A new model-independent physiological approach to study hepatic drug clearance and its applications. Chiou WL Int J Clin Pharmacol Ther Toxicol; 1984 Nov; 22(11):577-90. PubMed ID: 6389376 [TBL] [Abstract][Full Text] [Related]
2. Effect of diffusional barriers on drug and metabolite kinetics. de Lannoy IA; Pang KS Drug Metab Dispos; 1987; 15(1):51-8. PubMed ID: 2881759 [TBL] [Abstract][Full Text] [Related]
3. Effects of route of administration and blood flow on hepatic drug elimination. Shand DG; Kornhauser DM; Wilkinson GR J Pharmacol Exp Ther; 1975 Dec; 195(3):424-32. PubMed ID: 1195129 [TBL] [Abstract][Full Text] [Related]
4. A new simple approach to study the effect of changes in urine flow and/or urine pH on renal clearance and its applications. Chiou WL Int J Clin Pharmacol Ther Toxicol; 1986 Oct; 24(10):519-27. PubMed ID: 3781671 [TBL] [Abstract][Full Text] [Related]
5. [Hepatic clearance of drugs. Physiological and pharmacokinetic considerations]. Pellegrin P; Lesne M J Pharmacol; 1983; 14(2):107-39. PubMed ID: 6865443 [TBL] [Abstract][Full Text] [Related]
6. An integrated approach to model hepatic drug clearance. Liu L; Pang KS Eur J Pharm Sci; 2006 Nov; 29(3-4):215-30. PubMed ID: 16806855 [TBL] [Abstract][Full Text] [Related]
7. Prediction of hepatic extraction ratio from in vitro measurement of intrinsic clearance. Rane A; Wilkinson GR; Shand DG J Pharmacol Exp Ther; 1977 Feb; 200(2):420-4. PubMed ID: 839445 [TBL] [Abstract][Full Text] [Related]
8. Hepatic enzyme activity is the major factor determining elimination rate of high-clearance drugs in cirrhosis. Callaghan R; Desmond PV; Paull P; Mashford ML Hepatology; 1993 Jul; 18(1):54-60. PubMed ID: 8325621 [TBL] [Abstract][Full Text] [Related]
9. The series-compartment model for hepatic elimination. Gray MR; Tam YK Drug Metab Dispos; 1987; 15(1):27-31. PubMed ID: 2881755 [TBL] [Abstract][Full Text] [Related]
10. Computer simulations of bioequivalence trials: selection of design and analyte in BCS drugs with first-pass hepatic metabolism: linear kinetics (I). Fernández-Teruel C; Nalda Molina R; González-Alvarez I; Navarro-Fontestad C; García-Arieta A; Casabó VG; Bermejo M Eur J Pharm Sci; 2009 Jan; 36(1):137-46. PubMed ID: 19028574 [TBL] [Abstract][Full Text] [Related]
11. The area under the curve of metabolites for drugs and metabolites cleared by the liver and extrahepatic organs. Its dependence on the administration route of precursor drug. Klippert PJ; Noordhoek J Drug Metab Dispos; 1985; 13(1):97-101. PubMed ID: 2858385 [TBL] [Abstract][Full Text] [Related]
12. Models of hepatic elimination: implications from studies of the simultaneous elimination of taurocholate and diazepam by isolated rat liver under varying conditions of binding. Ching MS; Morgan DJ; Smallwood RA J Pharmacol Exp Ther; 1989 Sep; 250(3):1048-54. PubMed ID: 2778709 [TBL] [Abstract][Full Text] [Related]
13. Kinetic study of the hepatobiliary transport of a new prostaglandin receptor agonist. Imawaka H; Sugiyama Y J Pharmacol Exp Ther; 1998 Mar; 284(3):949-57. PubMed ID: 9495854 [TBL] [Abstract][Full Text] [Related]
17. Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics. Iwatsubo T; Hirota N; Ooie T; Suzuki H; Sugiyama Y Biopharm Drug Dispos; 1996 May; 17(4):273-310. PubMed ID: 8845471 [TBL] [Abstract][Full Text] [Related]
18. Models of hepatic drug elimination. Saville BA; Gray MR; Tam YK Drug Metab Rev; 1992; 24(1):49-88. PubMed ID: 1555493 [TBL] [Abstract][Full Text] [Related]
19. Effect of hematocrit and albumin concentration on hepatic clearance of tacrolimus (FK506) during rabbit liver perfusion. Chow FS; Piekoszewski W; Jusko WJ Drug Metab Dispos; 1997 May; 25(5):610-6. PubMed ID: 9152601 [TBL] [Abstract][Full Text] [Related]
20. The roles of transporters and enzymes in hepatic drug processing. Liu L; Pang KS Drug Metab Dispos; 2005 Jan; 33(1):1-9. PubMed ID: 15466164 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]