BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 6411095)

  • 1. 5'-deoxy-5'-methylthioadenosine phosphorylase--II. Role of the enzyme in the metabolism and antineoplastic action of adenine-substituted analogs of 5'-deoxy-5'-methylthioadenosine.
    Savarese TM; Dexter DL; Parks RE
    Biochem Pharmacol; 1983 Jun; 32(12):1907-16. PubMed ID: 6411095
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5'-deoxy-5'-methylthioadenosine phosphorylase--IV. Biological activity of 2-fluoroadenine-substituted 5'-deoxy-5'-methylthioadenosine analogs.
    Savarese TM; Cannistra AJ; Parks RE; Secrist JA; Shortnacy AT; Montgomery JA
    Biochem Pharmacol; 1987 Jun; 36(12):1881-93. PubMed ID: 3109431
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5'-Deoxy-5'-methylthioadenosine phosphorylase--III. Role of the enzyme in the metabolism and action of 5'-halogenated adenosine analogs.
    Savarese TM; Chu SH; Chu MY; Parks RE
    Biochem Pharmacol; 1985 Feb; 34(3):361-7. PubMed ID: 3918539
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Trypanosoma cruzi adenine nucleoside phosphorylase. Purification and substrate specificity.
    Miller RL; Sabourin CL; Krenitsky TA
    Biochem Pharmacol; 1987 Feb; 36(4):553-60. PubMed ID: 3103626
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of 5'-difluoromethylthioadenosine, an inhibitor of methylthioadenosine phosphorylase, on proliferation of cultured cells.
    Nishikawa S; Ueno A; Inoue H; Takeda Y
    J Cell Physiol; 1987 Nov; 133(2):372-6. PubMed ID: 3119605
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting 5'-deoxy-5'-(methylthio)adenosine phosphorylase by 5'-haloalkyl analogues of 5'-deoxy-5'-(methylthio)adenosine.
    Sufrin JR; Spiess AJ; Kramer DL; Libby PR; Miller JT; Bernacki RJ; Lee YH; Borchardt RT; Porter CW
    J Med Chem; 1991 Aug; 34(8):2600-6. PubMed ID: 1908523
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The comparative effects of 5'-methylthioadenosine and some of its analogs on cells containing, and deficient in, 5'-methylthioadenosine phosphorylase.
    White MW; Riscoe MK; Ferro AJ
    Biochim Biophys Acta; 1983 Jun; 762(3):405-13. PubMed ID: 6405800
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5'-Alkyl-substituted analogs of 5'-methylthioadenosine as trypanocides.
    Bacchi CJ; Sufrin JR; Nathan HC; Spiess AJ; Hannan T; Garofalo J; Alecia K; Katz L; Yarlett N
    Antimicrob Agents Chemother; 1991 Jul; 35(7):1315-20. PubMed ID: 1929287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural analogs of 5'-methylthioadenosine as substrates and inhibitors of 5'-methylthioadenosine phosphorylase and as inhibitors of human lymphocyte transformation.
    White MW; Vandenbark AA; Barney CL; Ferro AJ
    Biochem Pharmacol; 1982 Feb; 31(4):503-7. PubMed ID: 6802139
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of 5''-methylthioadenosine and its analogs on murine lymphoid cell proliferation.
    Wolford RW; MacDonald MR; Zehfus B; Rogers TJ; Ferro AJ
    Cancer Res; 1981 Aug; 41(8):3035-9. PubMed ID: 6788366
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of purines in human lymphoblast cells deficient in methylthioadenosine phosphorylase activity.
    Gordon RB; Blackwell K; Emmerson BT
    Biochim Biophys Acta; 1987 Jan; 927(1):1-7. PubMed ID: 3098299
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abnormal regulation of methylthioadenosine and polyamine metabolism in methylthioadenosine phosphorylase-deficient human leukemic cell lines.
    Kamatani N; Carson DA
    Cancer Res; 1980 Nov; 40(11):4178-82. PubMed ID: 6781742
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential regulation of polyamine synthesis and transmethylation reactions in methylthioadenosine phosphorylase deficient mammalian cells.
    Iizasa T; Carson DA
    Biochim Biophys Acta; 1985 Mar; 844(3):280-7. PubMed ID: 3918584
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conversion of 5'-deoxy-5'-methylthioadenosine and 5'-deoxy-5'-methylthioinosine to methionine in cultured human leukemic cells.
    Savarese TM; Ghoda LY; Dexter DL; Parks RE
    Cancer Res; 1983 Oct; 43(10):4699-702. PubMed ID: 6411330
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and antiproliferative effects of novel 5'-fluorinated analogues of 5'-deoxy-5'-(methylthio)adenosine.
    Sufrin JR; Spiess AJ; Kramer DL; Libby PR; Porter CW
    J Med Chem; 1989 May; 32(5):997-1001. PubMed ID: 2496231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. C(2')-substituted purine nucleoside analogs. Interactions with adenosine deaminase and purine nucleoside phosphorylase and formation of analog nucleotides.
    Stoeckler JD; Bell CA; Parks RE; Chu CK; Fox JJ; Ikehara M
    Biochem Pharmacol; 1982 May; 31(9):1723-8. PubMed ID: 6809009
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biosynthesis and metabolism of 9-[5'-deoxy-5'-(methylthio)-beta-D-xylofuranosyl]adenine, a novel natural analogue of methylthioadenosine.
    Porcelli M; Cacciapuoti G; Cimino G; Gavagnin M; Sodano G; Zappia V
    Biochem J; 1989 Nov; 263(3):635-40. PubMed ID: 2512910
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methionine recycling pathways and antimalarial drug design.
    Sufrin JR; Meshnick SR; Spiess AJ; Garofalo-Hannan J; Pan XQ; Bacchi CJ
    Antimicrob Agents Chemother; 1995 Nov; 39(11):2511-5. PubMed ID: 8585735
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Substrate specificities of 5'-deoxy-5'-methylthioadenosine phosphorylase from Trypanosoma brucei brucei and mammalian cells.
    Ghoda LY; Savarese TM; Northup CH; Parks RE; Garofalo J; Katz L; Ellenbogen BB; Bacchi CJ
    Mol Biochem Parasitol; 1988 Jan; 27(2-3):109-18. PubMed ID: 3125430
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synergistic inhibition of polyamine synthesis and growth by difluoromethylornithine plus methylthioadenosine in methylthioadenosine phosphorylase-deficient murine lymphoma cells.
    Yamanaka H; Kubota M; Carson DA
    Cancer Res; 1987 Apr; 47(7):1771-4. PubMed ID: 3102048
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.