These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 6433565)

  • 1. Aspects of the metabolism of valproic acid.
    Granneman GR; Wang SI; Machinist JM; Kesterson JW
    Xenobiotica; 1984 May; 14(5):375-87. PubMed ID: 6433565
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P-450-mediated dehydrogenation of 2-n-propyl-2(E)-pentenoic acid, a pharmacologically-active metabolite of valproic acid, in rat liver microsomal preparations.
    Kassahun K; Baillie TA
    Drug Metab Dispos; 1993; 21(2):242-8. PubMed ID: 8097692
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Studies on the metabolic fate of valproic acid in the rat using stable isotope techniques.
    Rettenmeier AW; Gordon WP; Barnes H; Baillie TA
    Xenobiotica; 1987 Oct; 17(10):1147-57. PubMed ID: 3122428
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats.
    Tong V; Teng XW; Karagiozov S; Chang TK; Abbott FS
    Free Radic Biol Med; 2005 Jun; 38(11):1471-83. PubMed ID: 15890621
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment.
    Boucher JL; Delaforge M; Salaün JP; Pinot F; Durst F; Pflieger P; Mioskowski C
    Drug Metab Dispos; 1996 Apr; 24(4):462-8. PubMed ID: 8801062
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The hepatotoxicity of valproic acid and its metabolites in rats. II. Intermediary and valproic acid metabolism.
    Granneman GR; Wang SI; Kesterson JW; Machinist JM
    Hepatology; 1984; 4(6):1153-8. PubMed ID: 6437961
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effect of inducers and inhibitors of glucuronidation on the biliary excretion and choleretic action of valproic acid in the rat.
    Watkins JB; Klaassen CD
    J Pharmacol Exp Ther; 1982 Feb; 220(2):305-10. PubMed ID: 6799642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The disposition of valpromide in rats and the isolated perfused rat liver.
    Billig H; Ziv E; Bar-On H; Bialer M
    Drug Metab Dispos; 1990; 18(2):238-44. PubMed ID: 1971580
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impaired biliary elimination of beta-glucuronidase-resistant "glucuronides" of valproic acid after intravenous administration in the rat. Evidence for oxidative metabolism of the resistant isomers.
    Dickinson RG; Kluck RM; Wood BT; Eadie MJ; Hooper WD
    Drug Metab Dispos; 1986; 14(2):255-62. PubMed ID: 2870903
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Biotransformation and pharmacokinetics in the rhesus monkey of 2-n-propyl-4-pentenoic acid, a toxic metabolite of valproic acid.
    Rettenmeier AW; Gordon WP; Prickett KS; Levy RH; Baillie TA
    Drug Metab Dispos; 1986; 14(4):454-64. PubMed ID: 2873993
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic fate of valproic acid in the rhesus monkey. Formation of a toxic metabolite, 2-n-propyl-4-pentenoic acid.
    Rettenmeier AW; Gordon WP; Prickett KS; Levy RH; Lockard JS; Thummel KE; Baillie TA
    Drug Metab Dispos; 1986; 14(4):443-53. PubMed ID: 2873992
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conjugation of glutathione with a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, catalyzed by rat hepatic glutathione-S-transferases.
    Tang W; Borel AG; Abbott FS
    Drug Metab Dispos; 1996 Apr; 24(4):436-46. PubMed ID: 8801059
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The hepatotoxicity of valproic acid and its metabolites in rats. I. Toxicologic, biochemical and histopathologic studies.
    Kesterson JW; Granneman GR; Machinist JM
    Hepatology; 1984; 4(6):1143-52. PubMed ID: 6437960
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Chemical and immunochemical comparison of protein adduct formation of four carboxylate drugs in rat liver and plasma.
    Bailey MJ; Dickinson RG
    Chem Res Toxicol; 1996; 9(3):659-66. PubMed ID: 8728513
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bioactivation of a toxic metabolite of valproic acid, (E)-2-propyl-2,4-pentadienoic acid, via glucuronidation. LC/MS/MS characterization of the GSH-glucuronide diconjugates.
    Tang W; Abbott FS
    Chem Res Toxicol; 1996 Mar; 9(2):517-26. PubMed ID: 8839057
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stereochemical studies on the beta-oxidation of valproic acid in isolated rat hepatocytes.
    Shirley MA; Hu P; Baillie TA
    Drug Metab Dispos; 1993; 21(4):580-6. PubMed ID: 8104116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of valproic acid on glycine conjugation of benzoic acid.
    Gregus Z; Fekete T; Varga F; Klaassen CD
    J Pharmacol Exp Ther; 1993 Dec; 267(3):1068-75. PubMed ID: 8263766
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alterations in the renal excretion of valproate and its metabolites after chronic treatment.
    Fisher JE; Nau H; Löscher W
    Epilepsia; 1991; 32(1):146-50. PubMed ID: 1985825
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies on the beta-oxidation of valproic acid in rat liver mitochondrial preparations.
    Bjorge SM; Baillie TA
    Drug Metab Dispos; 1991; 19(4):823-9. PubMed ID: 1680661
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.
    Kassahun K; Farrell K; Abbott F
    Drug Metab Dispos; 1991; 19(2):525-35. PubMed ID: 1676665
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.