These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

546 related articles for article (PubMed ID: 6437671)

  • 1. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
    Keyes SR; Fracasso PM; Heimbrook DC; Rockwell S; Sligar SG; Sartorelli AC
    Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Reversal of mitomycin C resistance by overexpression of bioreductive enzymes in Chinese hamster ovary cells.
    Baumann RP; Hodnick WF; Seow HA; Belcourt MF; Rockwell S; Sherman DH; Sartorelli AC
    Cancer Res; 2001 Nov; 61(21):7770-6. PubMed ID: 11691791
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reductive activation of mitomycin C by NADH:cytochrome b5 reductase.
    Hodnick WF; Sartorelli AC
    Cancer Res; 1993 Oct; 53(20):4907-12. PubMed ID: 8402680
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase.
    Dulhanty AM; Whitmore GF
    Cancer Res; 1991 Apr; 51(7):1860-5. PubMed ID: 1900739
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of mitomycin C by NADPH:cytochrome P-450 reductase.
    Bligh HF; Bartoszek A; Robson CN; Hickson ID; Kasper CB; Beggs JD; Wolf CR
    Cancer Res; 1990 Dec; 50(24):7789-92. PubMed ID: 2123741
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Generation of reactive oxygen radicals through bioactivation of mitomycin antibiotics.
    Pritsos CA; Sartorelli AC
    Cancer Res; 1986 Jul; 46(7):3528-32. PubMed ID: 3011250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [DT-diaphorase].
    Mikami K; Shirakusa T; Tsuruo T
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modification of the metabolism and cytotoxicity of bioreductive alkylating agents by dicoumarol in aerobic and hypoxic murine tumor cells.
    Keyes SR; Rockwell S; Sartorelli AC
    Cancer Res; 1989 Jun; 49(12):3310-3. PubMed ID: 2470504
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Exploring the mechanistic aspects of mitomycin antibiotic bioactivation in Chinese hamster ovary cells overexpressing NADPH:cytochrome C (P-450) reductase and DT-diaphorase.
    Belcourt MF; Hodnick WF; Rockwell S; Sartorelli AC
    Adv Enzyme Regul; 1998; 38():111-33. PubMed ID: 9762350
    [TBL] [Abstract][Full Text] [Related]  

  • 11. One-electron reduction of mitomycin c by rat liver: role of cytochrome P-450 and NADPH-cytochrome P-450 reductase.
    Vromans RM; van de Straat R; Groeneveld M; Vermeulen NP
    Xenobiotica; 1990 Sep; 20(9):967-78. PubMed ID: 2122607
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM; Sartorelli AC
    Cancer Res; 1986 Aug; 46(8):3939-44. PubMed ID: 3089583
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of glutathione and ethylxanthate on mitomycin C activation by isolated rat hepatic or EMT6 mouse mammary tumor nuclei.
    Kennedy KA; Mimnaugh EG; Trush MA; Sinha BK
    Cancer Res; 1985 Sep; 45(9):4071-6. PubMed ID: 2411396
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhancement of mitomycin C cytotoxicity to hypoxic tumor cells by dicoumarol in vivo and in vitro.
    Keyes SR; Rockwell S; Sartorelli AC
    Cancer Res; 1985 Jan; 45(1):213-6. PubMed ID: 2578093
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chemotherapeutic attack of hypoxic tumor cells by the bioreductive alkylating agent mitomycin C.
    Keyes SR; Heimbrook DC; Fracasso PM; Rockwell S; Sligar SG; Sartorelli AC
    Adv Enzyme Regul; 1985; 23():291-307. PubMed ID: 3934922
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
    Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic tumor cells.
    Kennedy KA; Rockwell S; Sartorelli AC
    Cancer Res; 1980 Jul; 40(7):2356-60. PubMed ID: 7388797
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
    Suresh Kumar G; Lipman R; Cummings J; Tomasz M
    Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
    Begleiter A; Leith MK
    Mol Pharmacol; 1993 Jul; 44(1):210-5. PubMed ID: 8341273
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of mitomycin C by DT-diaphorase: role in mitomycin C-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D; Gibson NW; Preusch PC; Ross D
    Cancer Res; 1990 Dec; 50(23):7483-9. PubMed ID: 1701346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.