116 related articles for article (PubMed ID: 6440717)
1. Electrostatic forces in the inhibition of dihydrofolate reductase by methotrexate. A field potential study.
Komatsu K; Nakamura H; Nakagawa S; Umeyama H
Chem Pharm Bull (Tokyo); 1984 Aug; 32(8):3313-6. PubMed ID: 6440717
[No Abstract] [Full Text] [Related]
2. Direct experimental evidence for competitive inhibition of dihydrofolate reductase by methotrexate.
Waltham MC; Holland JW; Robinson SC; Winzor DJ; Nixon PF
Biochem Pharmacol; 1988 Feb; 37(3):535-9. PubMed ID: 3122764
[TBL] [Abstract][Full Text] [Related]
3. Reduction of oxidised folates by dihydrofolate reductase from methotrexate-resistant Lactobacillus casei.
McIntyre LJ; Harding NG
Biochim Biophys Acta; 1977 Jun; 482(2):261-71. PubMed ID: 18181
[TBL] [Abstract][Full Text] [Related]
4. A 1H n.m.r. study of the role of the glutamate moiety in the binding of methotrexate to Lactobacillus casei dihydrofolate reductase.
Antonjuk DJ; Birdsall B; Cheung HT; Clore GM; Feeney J; Gronenborn A; Roberts GC; Tran TQ
Br J Pharmacol; 1984 Feb; 81(2):309-15. PubMed ID: 6423020
[TBL] [Abstract][Full Text] [Related]
5. Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei. Effects of pH, salts, temperature, and source of NADPH on enzyme activity and substrate specificity studies.
Williams TJ; Lee TK; Dunlap RB
Arch Biochem Biophys; 1977 Jun; 181(2):569-79. PubMed ID: 20050
[No Abstract] [Full Text] [Related]
6. Comparison of the inhibition of methotrexate-sensitive and -resistant Lactobacillus casei cell cultures with purified Lactobacillus casei dihydrofolate reductase by 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-substituted-phenyl)-s-triazines. Use of quantitative structure-activity relationships in making inferences about the mechanism of resistance and the structure of the enzyme is situ compared with the enzyme in vitro.
Coats EA; Genther CS; Dietrich SW; Guo ZR; Hansch C
J Med Chem; 1981 Dec; 24(12):1422-9. PubMed ID: 6796688
[TBL] [Abstract][Full Text] [Related]
7. TPNH-dependent binding of amethopterin by dihydrofolate reductase from Lactobacillus casei.
Otting F; Huennekens FM
Arch Biochem Biophys; 1972 Sep; 152(1):429-31. PubMed ID: 4403695
[No Abstract] [Full Text] [Related]
8. Methotrexate analogues. 14. Synthesis of new gamma-substituted derivatives as dihydrofolate reductase inhibitors and potential anticancer agents.
Rosowsky A; Forsch R; Uren J; Wick M
J Med Chem; 1981 Dec; 24(12):1450-5. PubMed ID: 6796689
[TBL] [Abstract][Full Text] [Related]
9. Methotrexate analogues. 12. Synthesis and biological properties of some aza homologues.
Martinelli JE; Chaykovsky M; Kisliuk RL; Gaumont Y; Gittelman MC
J Med Chem; 1979 Jul; 22(7):869-74. PubMed ID: 109616
[TBL] [Abstract][Full Text] [Related]
10. A 1H NMR study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase.
Birdsall B; Feeney J; Pascual C; Roberts GC; Kompis I; Then RL; Müller K; Kroehn A
J Med Chem; 1984 Dec; 27(12):1672-6. PubMed ID: 6438320
[TBL] [Abstract][Full Text] [Related]
11. 19F-n.m.r. studies of 3',5'-difluoromethotrexate binding to Lactobacillus casei dihydrofolate reductase. Molecular motion and coenzyme-induced conformational changes.
Clore GM; Gronenborn AM; Birdsall B; Feeney J; Roberts GC
Biochem J; 1984 Feb; 217(3):659-66. PubMed ID: 6424648
[TBL] [Abstract][Full Text] [Related]
12. Methotrexate analogues. 15. A methotrexate analogue designed for active-site-directed irreversible inactivation of dihydrofolate reductase.
Rosowsky A; Wright JE; Ginty C; Uren J
J Med Chem; 1982 Aug; 25(8):960-4. PubMed ID: 6811744
[TBL] [Abstract][Full Text] [Related]
13. Amino acid sequence of dihydrofolate reductase from an amethopterin-resistant strain of Lactobacillus casei.
Bitar KG; Blankenship DT; Walsh KA; Dunlap RB; Reddy AV; Freisheim JH
FEBS Lett; 1977 Aug; 80(1):119-22. PubMed ID: 408191
[No Abstract] [Full Text] [Related]
14. The charge state of substrates and inhibitors when bound to Lactobacillus casei dihydrofolate reductase [proceedings].
Hood K; Roberts GC
Biochem Soc Trans; 1977; 5(3):771-2. PubMed ID: 20381
[No Abstract] [Full Text] [Related]
15. Methotrexate analogues. 9. Synthesis and biological properties of some 8-alkyl-7,8-dihydro analogues.
Chaykovsky M; Hirst M; Lazarus H; Martinelli JE
J Med Chem; 1977 Oct; 20(10):1323-7. PubMed ID: 409842
[TBL] [Abstract][Full Text] [Related]
16. Dihydrofolate reductase from amethopterin-resistant Lactobacillus casei.
Gundersen LE; Dunlap RB; Harding NG; Freisheim JH; Otting F; Huennekens FM
Biochemistry; 1972 Mar; 11(6):1018-23. PubMed ID: 4401226
[No Abstract] [Full Text] [Related]
17. The use of triazine inhibitors in mapping the active site region of Lactobacillus casei dihydrofolate reductase.
Dietrich SW; Smith RN; Brendler S; Hansch C
Arch Biochem Biophys; 1979 May; 194(2):612-9. PubMed ID: 109047
[No Abstract] [Full Text] [Related]
18. Ultraviolet difference-spectroscopic studies of substrate and inhibitor binding to Lactobacillus casei dihydrofolate reductase.
Hood K; Roberts GC
Biochem J; 1978 May; 171(2):357-66. PubMed ID: 26334
[TBL] [Abstract][Full Text] [Related]
19. [Quantitative correlations of the inhibitory effects of triazines on the isolated dihydrofolate reductase from Lactobacillus casei cells and the cells in culture].
Guo ZR
Yao Xue Xue Bao; 1983 Jan; 18(1):33-8. PubMed ID: 6407279
[No Abstract] [Full Text] [Related]
20. Interaction of dihydrofolate reductase from amethopterin-resistant Lactobacillus casei with Cibacron Blue, Blue Dextran, and Affi-Gel Blue.
Chambers BB; Dunlap RB
J Biol Chem; 1979 Jul; 254(14):6515-21. PubMed ID: 109449
[No Abstract] [Full Text] [Related]
[Next] [New Search]
