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24. Structural comparisons of complexes of methotrexate analogues with Lactobacillus casei dihydrofolate reductase by two-dimensional 1H NMR at 500 MHz. Hammond SJ; Birdsall B; Feeney J; Searle MS; Roberts GC; Cheung HT Biochemistry; 1987 Dec; 26(26):8585-90. PubMed ID: 3126805 [TBL] [Abstract][Full Text] [Related]
25. Activity of the new antifolate N10-propargyl-5,8-dideazafolate and its polyglutamates against human dihydrofolate reductase, human thymidylate synthetase, and KB cells containing different levels of dihydrofolate reductase. Cheng YC; Dutschman GE; Starnes MC; Fisher MH; Nanavathi NT; Nair MG Cancer Res; 1985 Feb; 45(2):598-600. PubMed ID: 3917852 [TBL] [Abstract][Full Text] [Related]
26. Dihydrofolate reductase from Lactobacillus casei: N-terminal sequence and comparison with the substrate binding region of other reductases. Batley KE; Morris HR Biochem Biophys Res Commun; 1977 Apr; 75(4):1010-4. PubMed ID: 405008 [No Abstract] [Full Text] [Related]
27. Implication of a tryptophyl residue in the active site of dihydrofolate reductase. Liu JK; Dunlap RB Biochemistry; 1974 Apr; 13(9):1807-14. PubMed ID: 4151741 [No Abstract] [Full Text] [Related]
28. Methotrexate analogs. 4.7-Methyl derivatives of methotrexate and dichloromethotrexate. A new synthesis and some biological studies. Rosowsky A; Chen KK J Med Chem; 1974 Dec; 17(12):1308-11. PubMed ID: 4214928 [No Abstract] [Full Text] [Related]
29. 1H nuclear magnetic resonance studies of the tyrosine residues of selectively deuterated Lactobacillus casei dihydrofolate reductase. Feeney J; Roberts GC; Birdsall B; Griffiths DV; King RW; Scudder P; Burgen A Proc R Soc Lond B Biol Sci; 1977 Mar; 196(1124):267-90. PubMed ID: 16269 [No Abstract] [Full Text] [Related]
30. 1H nuclear magnetic resonance studies of Lactobacillus casei dihydrofolate reductase: effects of substrate and inhibitor binding on the histidine residues. Birdsall B; Griffiths DV; Roberts GC; Feeney J; Burgen A Proc R Soc Lond B Biol Sci; 1977 Mar; 196(1124):251-65. PubMed ID: 16268 [No Abstract] [Full Text] [Related]
31. Novel fluorinated antifolates. Enzyme inhibition and cytotoxicity studies on 2'- and 3'-fluoroaminopterin. Henkin J; Washtien WL J Med Chem; 1983 Aug; 26(8):1193-6. PubMed ID: 6410066 [TBL] [Abstract][Full Text] [Related]
32. Methotrexate analogues. 8. Synthesis and biological evaluation of bisamide derivatives as potential prodrugs. Rosowsky A; Ensminger WD; Lazarus H; Yu CS J Med Chem; 1977 Jul; 20(7):925-30. PubMed ID: 406398 [No Abstract] [Full Text] [Related]
34. Folate analogues altered in the C9--N10 bridge region. 14. 11-Oxahomofolic acid, a potential antitumor agent. Nair MG; Saunders C; Chen SY; Kisliuk RL; Gaumont Y J Med Chem; 1980 Jan; 23(1):59-65. PubMed ID: 6767031 [No Abstract] [Full Text] [Related]
35. Use of dihydrofolate reductase from bovine liver, rather than from L. casei, for determining methotrexate. Brooks RJ Clin Chem; 1978 Mar; 24(3):518-9. PubMed ID: 415830 [No Abstract] [Full Text] [Related]
37. Methotrexate analogues. 16. Importance of the side-chain amide carbonyl group as a structural determinant of biological activity. Rosowsky A; Forsch R J Med Chem; 1982 Dec; 25(12):1454-9. PubMed ID: 6818345 [TBL] [Abstract][Full Text] [Related]
38. An active center tryptophan residue in dihydrofolate reductase: chemical modification, sequence surrounding the critical residue, and structural homology considerations. Freisheim JH; Ericsson LH; Bitar KG; Dunlap RB; Reddy AV Arch Biochem Biophys; 1977 Apr; 180(2):310-7. PubMed ID: 406848 [No Abstract] [Full Text] [Related]
39. Folate antagonists covalently linked to carbohydrates: synthesis, properties, and use in the purification of dihydrofolate reductases. Whiteley JM; Jackson RC; Mell GP; Drais JH; Huennekens FM Arch Biochem Biophys; 1972 May; 150(1):15-22. PubMed ID: 4623864 [No Abstract] [Full Text] [Related]
40. Inhibition of dihydrofolate reductase: effect of reduced nicotinamide adenine dinucleotide phosphate on the selectivity and affinity of diaminobenzylpyrimidines. Baccanari DP; Daluge S; King RW Biochemistry; 1982 Sep; 21(20):5068-75. PubMed ID: 6814484 [No Abstract] [Full Text] [Related] [Previous] [Next] [New Search]