These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

84 related articles for article (PubMed ID: 6502602)

  • 1. A potent multisubstrate analogue inhibitor of human thymidylate synthetase.
    Srinivasan A; Amarnath V; Broom AD; Zou FC; Cheng YC
    J Med Chem; 1984 Dec; 27(12):1710-7. PubMed ID: 6502602
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Thymidylate synthetase inhibitors. Synthesis of N-substituted 5-aminomethyl-2'-deoxyuridine 5'-phosphates.
    Edelman MS; Barfknecht RL; Huet-Rose R; Boguslawski S; Mertes MP
    J Med Chem; 1977 May; 20(5):669-73. PubMed ID: 323484
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthetic inhibitors of Escherichia coli, calf thymus, and Ehrlich ascites tumor thymidylate synthetase.
    Kampf A; Barfknecht RL; Shaffer PJ; Osaki S; Mertes MP
    J Med Chem; 1976 Jul; 19(7):903-8. PubMed ID: 781246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase.
    Maggiora L; Chang CT; Hasson ME; Bigge CF; Mertes MP
    J Med Chem; 1983 Jul; 26(7):1028-36. PubMed ID: 6408258
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biochemical effects of a quinazoline inhibitor of thymidylate synthetase, N-(4-(N-(( 2-amino-4-hydroxy-6-quinazolinyl)methyl)prop-2-ynylamino) benzoyl)-L-glutamic acid (CB3717), on human lymphoblastoid cells.
    Jackson RC; Jackman AL; Calvert AH
    Biochem Pharmacol; 1983 Dec; 32(24):3783-90. PubMed ID: 6661252
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and antitumor and antiviral properties of 5-alkyl-2'-deoxyuridines, 3',5'-cyclic monophosphates, and neutral cyclic triesters.
    Bères J; Bentrude WG; Balzarini J; De Clercq E; Otvös L
    J Med Chem; 1986 Apr; 29(4):494-9. PubMed ID: 3959027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofolate reductase and thymidylate synthase and as potential antitumor agents.
    Gangjee A; Lin X; Kisliuk RL; McGuire JJ
    J Med Chem; 2005 Nov; 48(23):7215-22. PubMed ID: 16279780
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of two diastereoisomeric p-nitrophenyl phosphodiesters of 2',3'-secouridine and their affinity for phosphodiesterases.
    Jones AS; Niwas S; Tanaka H; Walker RT
    Nucleic Acids Res; 1986 Jul; 14(13):5409-16. PubMed ID: 3016646
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 5-selenium-substituted uracil derivatives. Inhibition of thymidylate synthetase by 5-hydroseleno-2'-deoxyuridylate.
    Choi S; Kalman TI; Bardos TJ
    J Med Chem; 1979 Jun; 22(6):618-21. PubMed ID: 110931
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of deoxyuridylate with thymidylate synthetase.
    Leary RP; Beaudette N; Kisliuk RL
    J Biol Chem; 1975 Jul; 250(13):4864-8. PubMed ID: 807570
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancement of 5-fluoro-2'-deoxyuridine antineoplastic activity by 5-benzyloxybenzyloxybenzylacyclouridine in a human colon carcinoma cell line.
    Chu E; Chu MY; Darnowski JW; Chen ZH; Pan BC; Chu SH
    Cancer Res; 1992 Apr; 52(7):1729-36. PubMed ID: 1532344
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fluorescent inhibitors of thymidylate synthetase.
    Deits TL; Gapski GR; Whiteley JM
    J Pharm Sci; 1977 Mar; 66(3):434-6. PubMed ID: 403277
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5-Cyano-2'-deoxyuridine 5'-phosphate: a potent competitive inhibitor of thymidylate synthetase.
    Chang CT; Edwards MW; Torrence PF; Mertes MP
    J Med Chem; 1979 Sep; 22(9):1137-9. PubMed ID: 114660
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Letter: 5-iodoacetamidomethyl-2'-deoxyuridine 5'-phosphate. A selective inhibitor of mammalian thymidylate synthetases.
    Barfknecht RL; Huet-Rose RA; Kampf A; Mertes MP
    J Am Chem Soc; 1976 Aug; 98(16):5041-3. PubMed ID: 950429
    [No Abstract]   [Full Text] [Related]  

  • 15. Polymer-linked 6-azauridine 5'-monophosphate, a resin of high bioaffinity to orotidine-5'-phosphate decarboxylase.
    Rosemeyer H; Seela F
    J Med Chem; 1979 Dec; 22(12):1545-7. PubMed ID: 94096
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of mammalian tumour thymidylate synthetase by 5-alkylated 2'-deoxyuridine 5'-phosphates.
    Rode W; Kulikowski T; Kedzierska B; Jastreboff M; Shugar D
    Biochem Pharmacol; 1984 Sep; 33(17):2699-705. PubMed ID: 6466380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of mammalian tumour thymidylate synthetase by 2'-deoxyuridine 5'-phosphate analogues.
    Rode W; Kulikowski T; Kedzierska B; Shugar D
    Drugs Exp Clin Res; 1986; 12(6-7):545-9. PubMed ID: 3743372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent dual thymidylate synthase and dihydrofolate reductase inhibitors: classical and nonclassical 2-amino-4-oxo-5-arylthio-substituted-6-methylthieno[2,3-d]pyrimidine antifolates.
    Gangjee A; Qiu Y; Li W; Kisliuk RL
    J Med Chem; 2008 Sep; 51(18):5789-97. PubMed ID: 18800768
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs.
    Tobias SC; Borch RF
    J Med Chem; 2001 Dec; 44(25):4475-80. PubMed ID: 11728193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. trans-5-(3,3,3-Trifluoro-1-propenyl-)-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.
    Wataya Y; Matsuda A; Santi DV; Bergstrom DE; Ruth JL
    J Med Chem; 1979 Apr; 22(4):339-40. PubMed ID: 430474
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 5.