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3. Microbial conversion of compactin (ML-236B) to ML-236A. Komagata D; Yamashita H; Endo A J Antibiot (Tokyo); 1986 Nov; 39(11):1574-7. PubMed ID: 3793626 [TBL] [Abstract][Full Text] [Related]
4. Microbial phosphorylation of compactin (ML-236B) and related compounds. Endo A; Yamashita H; Naoki H; Iwashita T; Mizukawa Y J Antibiot (Tokyo); 1985 Mar; 38(3):328-32. PubMed ID: 4008328 [TBL] [Abstract][Full Text] [Related]
5. Microbial hydroxylation of ML-236B (compactin). Studies on microorganisms capable of 3 beta-hydroxylation of ML-236B. Serizawa N; Serizawa S; Nakagawa K; Furuya K; Okazaki T; Terahara A J Antibiot (Tokyo); 1983 Jul; 36(7):887-91. PubMed ID: 6684108 [TBL] [Abstract][Full Text] [Related]
6. Purification and characterization of cytochrome P-450sca from Streptomyces carbophilus. ML-236B (compactin) induces a cytochrome P-450sca in Streptomyces carbophilus that hydroxylates ML-236B to pravastatin sodium (CS-514), a tissue-selective inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase. Matsuoka T; Miyakoshi S; Tanzawa K; Nakahara K; Hosobuchi M; Serizawa N Eur J Biochem; 1989 Oct; 184(3):707-13. PubMed ID: 2509201 [TBL] [Abstract][Full Text] [Related]
7. Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. 1976. Endo A; Kuroda M; Tanzawa K Atheroscler Suppl; 2004 Oct; 5(3):39-42. PubMed ID: 15531273 [No Abstract] [Full Text] [Related]
8. Compactin (ML-236B) and related compounds as potential cholesterol-lowering agents that inhibit HMG-CoA reductase. Endo A J Med Chem; 1985 Apr; 28(4):401-5. PubMed ID: 3981532 [No Abstract] [Full Text] [Related]
9. Microbial hydroxylation of compactin (ML-236B) and monacolin K. Yamashita H; Tsubokawa S; Endo A J Antibiot (Tokyo); 1985 May; 38(5):605-9. PubMed ID: 4040510 [TBL] [Abstract][Full Text] [Related]
10. Overaccumulation of 3-hydroxy-3-methylglutaryl-coenzyme-A reductase in a compactin(ML-236B)-resistant mouse cell line with defects in the regulation of its activity. Hasumi K; Yamada A; Shimizu Y; Endo A Eur J Biochem; 1987 May; 164(3):547-52. PubMed ID: 3569277 [TBL] [Abstract][Full Text] [Related]
11. A possible translational control of 3-hydroxy-3-methylglutaryl coenzyme A reductase induction by ML-236b(compactin) in isolated rat hepatocytes. Koizumi J; Mabuchi H; Takeda R; Okamoto H Biochem Biophys Res Commun; 1982 Sep; 108(1):240-6. PubMed ID: 7150285 [No Abstract] [Full Text] [Related]
13. Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. Endo A; Kuroda M; Tanzawa K FEBS Lett; 1976 Dec; 72(2):323-6. PubMed ID: 16386050 [No Abstract] [Full Text] [Related]
14. Effects of ML-236b (compactin) on sterol synthesis and low density lipoprotein receptor activities in fibroblasts of patients with homozygous familial hypercholesterolemia. Haba T; Mabuchi H; Yoshimura A; Watanabe A; Wakasugi T; Tatami R; Ueda K; Ueda R; Kametani T; Koizumi J; Miyamoto S; Takeda R; Takeshita H J Clin Invest; 1981 May; 67(5):1532-40. PubMed ID: 7229037 [TBL] [Abstract][Full Text] [Related]
15. A quantitative analysis of nuclear magnetic relaxation: the configuration and the conformation of ML-236B (mevastatin) metabolites. Haruyama H; Kondo M Chem Pharm Bull (Tokyo); 1987 Jan; 35(1):170-81. PubMed ID: 3594648 [No Abstract] [Full Text] [Related]
16. Formation of dihydroxy derivative of ML-236B from ML-236B (compactin) by lipid peroxidation. Serizawa N; Nakahara K; Matsuoka T J Antibiot (Tokyo); 1990 Aug; 43(8):1031-3. PubMed ID: 2120167 [No Abstract] [Full Text] [Related]
17. Taxonomy of actinomycetes capable of hydroxylation of ML-236B (compactin). Okazaki T; Serizawa N; Enokita R; Torikata A; Terahara A J Antibiot (Tokyo); 1983 Sep; 36(9):1176-83. PubMed ID: 6630076 [TBL] [Abstract][Full Text] [Related]
18. Blocking 3-hydroxy-3-methylglutaryl coenzyme A reductase with ML-236B enhances the plasma cortisol response to adrenocorticotropin in patients with hypercholesterolemia. Yamaguchi K; Nakamura N; Uzawa H J Clin Endocrinol Metab; 1984 May; 58(5):786-9. PubMed ID: 6323515 [TBL] [Abstract][Full Text] [Related]
19. Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in human fibroblasts incubated with compactin (ML-236B), a competitive inhibitor of the reductase. Brown MS; Faust JR; Goldstein JL; Kaneko I; Endo A J Biol Chem; 1978 Feb; 253(4):1121-8. PubMed ID: 624722 [No Abstract] [Full Text] [Related]
20. Metabolism of naphthalene by Cunninghamella elegans. Cerniglia CE; Gibson DT Appl Environ Microbiol; 1977 Oct; 34(4):363-70. PubMed ID: 921262 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]