BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 6577945)

  • 1. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
    Boberg EW; Miller EC; Miller JA; Poland A; Liem A
    Cancer Res; 1983 Nov; 43(11):5163-73. PubMed ID: 6577945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens.
    Wislocki PG; Borchert P; Miller JA; Miller EC
    Cancer Res; 1976 May; 36(5):1686-95. PubMed ID: 5188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Further characterization of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1'-hydroxysafrole and 1'-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues.
    Wiseman RW; Fennell TR; Miller JA; Miller EC
    Cancer Res; 1985 Jul; 45(7):3096-105. PubMed ID: 4005847
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
    Miller EC; Swanson AB; Phillips DH; Fletcher TL; Liem A; Miller JA
    Cancer Res; 1983 Mar; 43(3):1124-34. PubMed ID: 6825084
    [TBL] [Abstract][Full Text] [Related]  

  • 5. N-sulfoöxy-2-aminofluorene is the major ultimate electrophilic and carcinogenic metabolite of N-hydroxy-2-acetylaminofluorene in the livers of infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.
    Lai CC; Miller JA; Miller EC; Liem A
    Carcinogenesis; 1985 Jul; 6(7):1037-45. PubMed ID: 3860305
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Major role of hepatic sulfotransferase activity in the metabolic activation, DNA adduct formation, and carcinogenicity of 1'-hydroxy-2',3'-dehydroestragole in infant male C57BL/6J x C3H/HeJ F1 mice.
    Fennell TR; Wiseman RW; Miller JA; Miller EC
    Cancer Res; 1985 Nov; 45(11 Pt 1):5310-20. PubMed ID: 3863702
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver.
    Boberg EW; Liem A; Miller EC; Miller JA
    Carcinogenesis; 1987 Apr; 8(4):531-9. PubMed ID: 2881629
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of the biliary and urinary glutathione and N-acetylcysteine metabolites of the hepatic carcinogen 1'-hydroxysafrole and its 1'-oxo metabolite in rats and mice.
    Fennell TR; Miller JA; Miller EC
    Cancer Res; 1984 Aug; 44(8):3231-40. PubMed ID: 6744260
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sulfuric acid esters as major ultimate electrophilic and hepatocarcinogenic metabolites of 4-aminoazobenzene and its N-methyl derivatives in infant male C57BL/6J x C3H/HeJ F1 (B6C3F1) mice.
    Delclos KB; Miller EC; Miller JA; Liem A
    Carcinogenesis; 1986 Feb; 7(2):277-87. PubMed ID: 2419005
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo.
    Phillips DH; Miller JA; Miller EC; Adams B
    Cancer Res; 1981 Jul; 41(7):2664-71. PubMed ID: 7248936
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Toxicology and Carcinogenesis Studies of 5,5-Diphenylhydantoin (CAS No. 57-41-0) (Phenytoin) in F344/N Rats and B6C3F1 Mice (Feed Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 1993 Nov; 404():1-303. PubMed ID: 12621514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4-aminoazobenzene and N,N-dimethyl-4-aminoazobenzene as equipotent hepatic carcinogens in male C57BL/6 X C3H/He F1 mice and characterization of N-(Deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice.
    Delclos KB; Tarpley WG; Miller EC; Miller JA
    Cancer Res; 1984 Jun; 44(6):2540-50. PubMed ID: 6426782
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole.
    Boberg EW; Miller EC; Miller JA
    Chem Biol Interact; 1986; 59(1):73-97. PubMed ID: 3757147
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice.
    Wiseman RW; Miller EC; Miller JA; Liem A
    Cancer Res; 1987 May; 47(9):2275-83. PubMed ID: 3567921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NTP Toxicology and Carcinogenesis Studies of Pentachloroanisole (CAS No. 1825-21-4) in F344 Rats and B6C3F1 Mice (Feed Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 1993 Apr; 414():1-284. PubMed ID: 12616284
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NTP Toxicology and Carcinogenesis Studies of Two Pentachlorophenol Technical-Grade Mixtures (CAS No. 87-86-5) in B6C3F1 Mice (Feed Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 1989 Mar; 349():1-265. PubMed ID: 12704435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver.
    Miller EC; Miller JA; Boberg EW; Delclos KB; Lai CC; Fennell TR; Wiseman RW; Liem A
    Carcinog Compr Surv; 1985; 10():93-107. PubMed ID: 3904999
    [No Abstract]   [Full Text] [Related]  

  • 19. NTP Toxicology and Carcinogenesis Studies of Polybrominated Biphenyls (CAS No. 67774-32-7)(Firemaster FF-1(R)) in F344/N Rats and B6C3F1 Mice (Feed Studies).
    National Toxicology Program
    Natl Toxicol Program Tech Rep Ser; 1993 Aug; 398():1-235. PubMed ID: 12637961
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts.
    Lai CC; Miller EC; Miller JA; Liem A
    Carcinogenesis; 1987 Mar; 8(3):471-8. PubMed ID: 3815742
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.