BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

400 related articles for article (PubMed ID: 6646150)

  • 1. Cytotoxicity of monofunctional alkylating agents. Methyl methanesulfonate and methyl-N'-nitro-N-nitrosoguanidine have different mechanisms of toxicity for 10T1/2 cells.
    Smith GJ; Grisham JW
    Mutat Res; 1983 Nov; 111(3):405-17. PubMed ID: 6646150
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cell killing by various monofunctional alkylating agents in Chinese hamster ovary cells.
    Goth-Goldstein R; Hughes M
    Mutat Res; 1987 Apr; 177(2):267-76. PubMed ID: 3561426
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between O6-alkylguanine-DNA alkyltransferase activity and N-methyl-N'-nitro-N-nitrosoguanidine-induced mutation, transformation, and cytotoxicity in C3H/10T1/2 cells expressing exogenous alkyltransferase genes.
    von Hofe E; Fairbairn L; Margison GP
    Proc Natl Acad Sci U S A; 1992 Dec; 89(23):11199-203. PubMed ID: 1454799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rat hepatocytes with elevated metallothionein expression are resistant to N-methyl-N'-nitro-N-nitrosoguanidine cytotoxicity.
    Moffatt P; Plaa GL; Denizeau F
    Toxicol Appl Pharmacol; 1996 Jan; 136(1):200-7. PubMed ID: 8560476
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-ray induction of O6-alkylguanine-DNA alkyltransferase protects against some of the biological effects of N-methyl-N'-nitro-N-nitrosoguanidine in C3H 10T1/2 cells.
    von Hofe E; Kennedy AR
    Radiat Res; 1991 Aug; 127(2):220-5. PubMed ID: 1947007
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Adaptive response in mammalian cells: crossreactivity of different pretreatments on cytotoxicity as contrasted to mutagenicity.
    Laval F; Laval J
    Proc Natl Acad Sci U S A; 1984 Feb; 81(4):1062-6. PubMed ID: 6583696
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cycle-related toxicity and transformation in 10T1/2 cells treated with N-methyl-N'-nitro-N-nitrosoguanidine.
    Grisham JW; Greenberg DS; Kaufman DG; Smith GJ
    Proc Natl Acad Sci U S A; 1980 Aug; 77(8):4813-7. PubMed ID: 6933531
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
    Dosch J; Kaina B
    Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Morphological transformation of C3H/10T1/2 CL8 cells by alkylating agents.
    Oshiro Y; Balwierz PS; Molinary SV
    Toxicol Lett; 1981 Dec; 9(4):301-6. PubMed ID: 7330894
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.
    Kaina B; Fritz G; Mitra S; Coquerelle T
    Carcinogenesis; 1991 Oct; 12(10):1857-67. PubMed ID: 1657427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetics of cell death induced in 10T1/2 cells by methyl methanesulfonate and the effects of extracellular calcium on cell death.
    Smith GJ; Grisham JW; Fatteh MM
    Am J Pathol; 1986 Mar; 122(3):488-92. PubMed ID: 3953771
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of chemical mediated cytotoxicity and chemoprotection in isolated rat hepatocytes.
    Shertzer HG; Sainsbury M; Graupner PR; Berger ML
    Chem Biol Interact; 1991; 78(2):123-41. PubMed ID: 2040020
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of foci of morphologically transformed cells in synchronized populations of 10T1/2 cells by N-methyl-N'-nitro-N-nitrosoguanidine and the effect of spontaneous transformation on calculated transformation frequency.
    Grisham JW; Smith GJ; Lee LW; Bentley KS; Fatteh MV
    Cancer Res; 1988 Nov; 48(21):5977-83. PubMed ID: 2844394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Toxicity of methylating agents in isolated hepatocytes.
    Reitman FA; Shertzer HG; Berger ML
    Biochem Pharmacol; 1988 Aug; 37(16):3183-8. PubMed ID: 3401249
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cross-resistance studies with V79 Chinese hamster cells adapted to the mutagenic or clastogenic effect of N-methyl-N'-nitro-N-nitrosoguanidine.
    Kaina B
    Mutat Res; 1983 Nov; 111(3):341-52. PubMed ID: 6646146
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA repair and sensitivity of mouse embryo fibroblasts to methyl methanesulphonate and N-methyl-N'-nitro-N-nitrosoguanidine.
    Anuszewska E; Koziorowska J
    Acta Biochim Pol; 1985; 32(4):295-304. PubMed ID: 3832702
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cellular resistance and hypermutability in mismatch repair-deficient human cancer cell lines following treatment with methyl methanesulfonate.
    Glaab WE; Risinger JI; Umar A; Barrett JC; Kunkel TA; Tindall KR
    Mutat Res; 1998 Feb; 398(1-2):197-207. PubMed ID: 9626980
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monofunctional alkylating agent-induced S-phase-dependent DNA damage.
    Schwartz JL
    Mutat Res; 1989 Apr; 216(2):111-8. PubMed ID: 2927413
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deoxyribonucleoside-induced selective modulation of cytotoxicity and mutagenesis.
    Peterson AR; Danenberg PV; Ibric LL; Peterson H
    Basic Life Sci; 1985; 31():313-34. PubMed ID: 3158302
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative assessment of the role of O6-methylguanine in the initiation of carcinogenesis by methylating agents.
    Doniger J; Day RS; DiPaolo JA
    Proc Natl Acad Sci U S A; 1985 Jan; 82(2):421-5. PubMed ID: 3855560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.