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6. Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells. Flintoff WF; Weber MK; Nagainis CR; Essani AK; Robertson D; Salser W Mol Cell Biol; 1982 Mar; 2(3):275-85. PubMed ID: 6287233 [TBL] [Abstract][Full Text] [Related]
7. Dihydrofolate reductase gene amplification and possible rearrangement in estrogen-responsive methotrexate-resistant human breast cancer cells. Cowan KH; Goldsmith ME; Levine RM; Aitken SC; Douglass E; Clendeninn N; Nienhuis AW; Lippman ME J Biol Chem; 1982 Dec; 257(24):15079-86. PubMed ID: 7174686 [TBL] [Abstract][Full Text] [Related]
8. Resistance to methotrexate due to gene amplification in a patient with acute leukemia. Carman MD; Schornagel JH; Rivest RS; Srimatkandada S; Portlock CS; Duffy T; Bertino JR J Clin Oncol; 1984 Jan; 2(1):16-20. PubMed ID: 6583326 [TBL] [Abstract][Full Text] [Related]
9. Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes. Kaufman RJ; Brown PC; Schimke RT Proc Natl Acad Sci U S A; 1979 Nov; 76(11):5669-73. PubMed ID: 293670 [TBL] [Abstract][Full Text] [Related]
10. Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug. Srimatkandada S; Schweitzer BI; Moroson BA; Dube S; Bertino JR J Biol Chem; 1989 Feb; 264(6):3524-8. PubMed ID: 2914962 [TBL] [Abstract][Full Text] [Related]
11. Coamplification of 3-hydroxy-3-methylglutaryl coenzyme A reductase genes in methotrexate-resistant human leukemia cell lines. Srimatkandada S; Dube SK; Carmen M; Bertino JR Oncol Res; 2000; 12(1):11-5. PubMed ID: 11061341 [TBL] [Abstract][Full Text] [Related]
12. Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. Nunberg JH; Kaufman RJ; Schimke RT; Urlaub G; Chasin LA Proc Natl Acad Sci U S A; 1978 Nov; 75(11):5553-6. PubMed ID: 281704 [TBL] [Abstract][Full Text] [Related]
13. A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variants. Fougere-Deschatrette C; Schimke RT; Weil D; Weiss MC J Cell Biol; 1984 Aug; 99(2):497-502. PubMed ID: 6746737 [TBL] [Abstract][Full Text] [Related]
14. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate. Assaraf YG; Molina A; Schimke RT J Biol Chem; 1989 Nov; 264(31):18326-34. PubMed ID: 2572592 [TBL] [Abstract][Full Text] [Related]
15. Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines. Kaufman RJ; Brown PC; Schimke RT Mol Cell Biol; 1981 Dec; 1(12):1084-93. PubMed ID: 7346713 [TBL] [Abstract][Full Text] [Related]
16. Effects of 5-fluorouracil on dihydrofolate reductase and dihydrofolate reductase mRNA from methotrexate-resistant KB cells. Dolnick BJ; Pink JJ J Biol Chem; 1985 Mar; 260(5):3006-14. PubMed ID: 3972814 [TBL] [Abstract][Full Text] [Related]
17. Relationship of amplified dihydrofolate reductase genes to double minute chromosomes in unstably resistant mouse fibroblast cell lines. Brown PC; Beverley SM; Schimke RT Mol Cell Biol; 1981 Dec; 1(12):1077-83. PubMed ID: 6287217 [TBL] [Abstract][Full Text] [Related]
18. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Milbrandt JD; Heintz NH; White WC; Rothman SM; Hamlin JL Proc Natl Acad Sci U S A; 1981 Oct; 78(10):6043-7. PubMed ID: 6273843 [TBL] [Abstract][Full Text] [Related]
19. Dihydrofolate reductase gene expression characterized by the PCR assay in human leukemia cells. Miyachi H; Han H; Scanlon KJ In Vivo; 1991; 5(1):7-12. PubMed ID: 1932630 [TBL] [Abstract][Full Text] [Related]