BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

505 related articles for article (PubMed ID: 6744260)

  • 1. Characterization of the biliary and urinary glutathione and N-acetylcysteine metabolites of the hepatic carcinogen 1'-hydroxysafrole and its 1'-oxo metabolite in rats and mice.
    Fennell TR; Miller JA; Miller EC
    Cancer Res; 1984 Aug; 44(8):3231-40. PubMed ID: 6744260
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Further characterization of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1'-hydroxysafrole and 1'-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues.
    Wiseman RW; Fennell TR; Miller JA; Miller EC
    Cancer Res; 1985 Jul; 45(7):3096-105. PubMed ID: 4005847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens.
    Wislocki PG; Borchert P; Miller JA; Miller EC
    Cancer Res; 1976 May; 36(5):1686-95. PubMed ID: 5188
    [TBL] [Abstract][Full Text] [Related]  

  • 4. N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo.
    Phillips DH; Miller JA; Miller EC; Adams B
    Cancer Res; 1981 Jul; 41(7):2664-71. PubMed ID: 7248936
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The in vivo formation and repair of DNA adducts from 1'-hydroxysafrole.
    Phillips DH; Hanawalt PC; Miller JA; Miller EC
    J Supramol Struct Cell Biochem; 1981; 16(1):83-90. PubMed ID: 7299840
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
    Boberg EW; Miller EC; Miller JA; Poland A; Liem A
    Cancer Res; 1983 Nov; 43(11):5163-73. PubMed ID: 6577945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification and characterization of the glutathione and N-acetylcysteine conjugates of (E)-2-propyl-2,4-pentadienoic acid, a toxic metabolite of valproic acid, in rats and humans.
    Kassahun K; Farrell K; Abbott F
    Drug Metab Dispos; 1991; 19(2):525-35. PubMed ID: 1676665
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole.
    Boberg EW; Miller EC; Miller JA
    Chem Biol Interact; 1986; 59(1):73-97. PubMed ID: 3757147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The metabolism and excretion of 14C-styrene oxide-glutathione adducts administered to the winter flounder, Pseudopleuronectes americanus, a marine teleost. Identification of the corresponding S-cysteine derivatives as major urinary metabolites.
    Yagen B; Foureman GL; Ben-Zvi Z; Ryan AJ; Hernandez O; Cox RH; Bend JR
    Drug Metab Dispos; 1984; 12(4):389-95. PubMed ID: 6148203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of biliary metabolites of m-dichlorobenzene in rats.
    Kimura R; Ohishi N; Kato Y; Yamada S; Sato M
    Drug Metab Dispos; 1992; 20(2):161-71. PubMed ID: 1352205
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of isosafrole and dihydrosafrole in the rat.
    Klungsøyr J; Scheline RR
    Biomed Mass Spectrom; 1982 Aug; 9(8):323-9. PubMed ID: 7126764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
    Miller EC; Swanson AB; Phillips DH; Fletcher TL; Liem A; Miller JA
    Cancer Res; 1983 Mar; 43(3):1124-34. PubMed ID: 6825084
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biotransformation of carbon-14-labeled muraglitazar in male mice: interspecies difference in metabolic pathways leading to unique metabolites.
    Li W; Zhang D; Wang L; Zhang H; Cheng PT; Zhang D; Everett DW; Humphreys WG
    Drug Metab Dispos; 2006 May; 34(5):807-20. PubMed ID: 16467134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HPLC-NMR with severe column overloading: fast-track metabolite identification in urine and bile samples from rat and dog treated with [14C]-ZD6126.
    Lenz EM; D'Souza RA; Jordan AC; King CD; Smith SM; Phillips PJ; McCormick AD; Roberts DW
    J Pharm Biomed Anal; 2007 Feb; 43(3):1065-77. PubMed ID: 17030109
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutathione conjugation of 1,2-dibromo-1-phenylethane in rats in vivo.
    Zoetemelk CE; van Hove W; van der Laan WL; van Meeteren-Wälchli B; van der Gen A; Breimer DD
    Drug Metab Dispos; 1987; 15(3):418-25. PubMed ID: 2886321
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Excretion of the mercapturic acid S-[2-(N7-guanyl)ethyl]-N-acetylcysteine in urine following administration of ethylene dibromide to rats.
    Kim DH; Guengerich FP
    Cancer Res; 1989 Nov; 49(21):5843-7. PubMed ID: 2790795
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The metabolism and excretion of styrene oxide-glutathione conjugates in the rat and by isolated perfused liver, lung and kidney preparations.
    Steele JW; Yagen B; Hernandez O; Cox RH; Smith BR; Bend JR
    J Pharmacol Exp Ther; 1981 Oct; 219(1):35-41. PubMed ID: 7288613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. alpha-Bromoisovalerylurea as model substrate for studies on pharmacokinetics of glutathione conjugation in the rat. I. (Bio-) synthesis, analysis and identification of diastereomeric glutathione conjugates and mercapturates.
    te Koppele JM; van der Mark EJ; Olde Boerrigter JC; Brussee J; van der Gen A; van der Greef J; Mulder GJ
    J Pharmacol Exp Ther; 1986 Dec; 239(3):898-904. PubMed ID: 3795048
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of ticlopidine in rats: identification of the main biliary metabolite as a glutathione conjugate of ticlopidine S-oxide.
    Shimizu S; Atsumi R; Nakazawa T; Fujimaki Y; Sudo K; Okazaki O
    Drug Metab Dispos; 2009 Sep; 37(9):1904-15. PubMed ID: 19541827
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NTP technical report on the toxicity and metabolism studies of chloral hydrate (CAS No. 302-17-0). Administered by gavage to F344/N rats and B6C3F1 mice.
    Beland FA
    Toxic Rep Ser; 1999 Aug; (59):1-66, A1-E7. PubMed ID: 11803702
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.