BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 6759038)

  • 1. Use of isotope effects to elucidate enzyme mechanisms.
    Cleland WW
    CRC Crit Rev Biochem; 1982; 13(4):385-428. PubMed ID: 6759038
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The use of isotope effects to determine enzyme mechanisms.
    Cleland WW
    Arch Biochem Biophys; 2005 Jan; 433(1):2-12. PubMed ID: 15581561
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of isotope effects to deduce the chemical mechanism of fumarase.
    Blanchard JS; Cleland WW
    Biochemistry; 1980 Sep; 19(19):4506-13. PubMed ID: 7407088
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isotope effects in the elucidation of enzyme mechanisms.
    Botting NP
    Nat Prod Rep; 1994 Aug; 11(4):337-53. PubMed ID: 15200018
    [No Abstract]   [Full Text] [Related]  

  • 5. Determination of the rate-limiting steps for malic enzyme by the use of isotope effects and other kinetic studies.
    Schimerlik MI; Grimshaw CE; Cleland WW
    Biochemistry; 1977 Feb; 16(4):571-6. PubMed ID: 13820
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Interpretation of V/K isotope effects for enzymatic reactions exhibiting multiple isotopically sensitive steps.
    Ruszczycky MW; Anderson VE
    J Theor Biol; 2006 Dec; 243(3):328-42. PubMed ID: 16914160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase.
    Cook PF; Cleland WW
    Biochemistry; 1981 Mar; 20(7):1805-16. PubMed ID: 7013801
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Use of multiple isotope effects to study the mechanism of 6-phosphogluconate dehydrogenase.
    Rendina AR; Hermes JD; Cleland WW
    Biochemistry; 1984 Dec; 23(25):6257-62. PubMed ID: 6395897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Minimal kinetic mechanism and general equation for deuterium isotope effects on enzymic reactions: uncertainty in detecting a rate-limiting step.
    Northrop DB
    Biochemistry; 1981 Jul; 20(14):4056-61. PubMed ID: 7284308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic deuterium isotope effects for 7-alkoxycoumarin O-dealkylation reactions catalyzed by human cytochromes P450 and in liver microsomes. Rate-limiting C-H bond breaking in cytochrome P450 1A2 substrate oxidation.
    Kim KH; Isin EM; Yun CH; Kim DH; Guengerich FP
    FEBS J; 2006 May; 273(10):2223-31. PubMed ID: 16649998
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbon-13 and deuterium isotope effects on the reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase.
    Canellas PF; Cleland WW
    Biochemistry; 1991 Sep; 30(36):8871-6. PubMed ID: 1888744
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Use of nitrogen-15 and deuterium isotope effects to determine the chemical mechanism of phenylalanine ammonia-lyase.
    Hermes JD; Weiss PM; Cleland WW
    Biochemistry; 1985 Jun; 24(12):2959-67. PubMed ID: 3893533
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 2. Formate dehydrogenase.
    Hermes JD; Morrical SW; O'Leary MH; Cleland WW
    Biochemistry; 1984 Nov; 23(23):5479-88. PubMed ID: 6391544
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of intermediate partitioning to calculate intrinsic isotope effects for the reaction catalyzed by malic enzyme.
    Grissom CB; Cleland WW
    Biochemistry; 1985 Feb; 24(4):944-8. PubMed ID: 3995001
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Examining the relative timing of hydrogen abstraction steps during NAD(+)-dependent oxidation of secondary alcohols catalyzed by long-chain D-mannitol dehydrogenase from Pseudomonas fluorescens using pH and kinetic isotope effects.
    Klimacek M; Nidetzky B
    Biochemistry; 2002 Aug; 41(31):10158-65. PubMed ID: 12146981
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analysis of the kinetic isotope effects on initial rates in transient kinetics.
    Palfey BA; Fagan RL
    Biochemistry; 2006 Nov; 45(45):13631-40. PubMed ID: 17087517
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Substrate specificity and kinetic isotope effect analysis of the Eschericia coli ketopantoate reductase.
    Zheng R; Blanchard JS
    Biochemistry; 2003 Sep; 42(38):11289-96. PubMed ID: 14503879
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Secondary isotope effects and structure-reactivity correlations in the dopamine beta-monooxygenase reaction: evidence for a chemical mechanism.
    Miller SM; Klinman JP
    Biochemistry; 1985 Apr; 24(9):2114-27. PubMed ID: 3995006
    [TBL] [Abstract][Full Text] [Related]  

  • 19. pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same.
    Cook PF; Cleland WW
    Biochemistry; 1981 Mar; 20(7):1797-805. PubMed ID: 7013800
    [No Abstract]   [Full Text] [Related]  

  • 20. Human erythrocyte glutathione reductase: chemical mechanism and structure of the transition state for hydride transfer.
    Sweet WL; Blanchard JS
    Biochemistry; 1991 Sep; 30(35):8702-9. PubMed ID: 1888731
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.