These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 6780280)

  • 1. Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues.
    Boyd MR
    Ciba Found Symp; 1980; 76():43-66. PubMed ID: 6780280
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of hepatic metabolism on the production and toxicity of reactive metabolites in extrahepatic organs.
    Boyd MR; Statham CN
    Drug Metab Rev; 1983; 14(1):35-47. PubMed ID: 6839941
    [No Abstract]   [Full Text] [Related]  

  • 3. The in vitro formation of glutathione conjugates with the microsomally activated pulmonary bronchiolar aklylating agent and cytotoxin, 4-ipomeanol.
    Buckpitt AR; Boyd MR
    J Pharmacol Exp Ther; 1980 Oct; 215(1):97-103. PubMed ID: 7452496
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation and detoxification of bromobenzene in extrahepatic tissues.
    Monks TJ; Lau SS
    Life Sci; 1984 Jul; 35(5):561-8. PubMed ID: 6748863
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vivo studies on the relationship between target organ alkylation and the pulmonary toxicity of a chemically reactive metabolite of 4-ipomeanol.
    Boyd MR; Burka LT
    J Pharmacol Exp Ther; 1978 Dec; 207(3):687-97. PubMed ID: 731424
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Extrahepatic targets and cellular reactivity of drug metabolites.
    Orhan H
    Curr Med Chem; 2015; 22(4):408-37. PubMed ID: 25174932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of ratios of covalent binding to total metabolism of the pulmonary toxin, 4-ipomeanol, in vitro in pulmonary and hepatic microsomes, and the effects of pretreatments with phenobarbital or 3-methylcholanthrene.
    Boyd MR; Sasame HA; Franklin RB
    Biochem Biophys Res Commun; 1980 Apr; 93(4):1167-72. PubMed ID: 7396903
    [No Abstract]   [Full Text] [Related]  

  • 8. Renal toxicity due to reactive metabolites formed in situ in the kidney: investigations with 4-ipomeanol in the mouse.
    Boyd MR; Dutcher JS
    J Pharmacol Exp Ther; 1981 Mar; 216(3):640-6. PubMed ID: 7205642
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of phenobarbital and 3-methylcholanthrene on the in vivo distribution, metabolism and covalent binding of 4-ipomeanol in the rat; implications for target organ toxicity.
    Statham CN; Boyd MR
    Biochem Pharmacol; 1982 Dec; 31(24):3973-7. PubMed ID: 7159474
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Evidence for hepatic formation, export and covalent binding of reactive naphthalene metabolites in extrahepatic tissues in vivo.
    Buckpitt AR; Warren DL
    J Pharmacol Exp Ther; 1983 Apr; 225(1):8-16. PubMed ID: 6834280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Hepatic metabolism and pulmonary toxicity of monocrotaline using isolated perfused liver and lung.
    Lafranconi WM; Huxtable RJ
    Biochem Pharmacol; 1984 Aug; 33(15):2479-84. PubMed ID: 6087830
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver.
    Orrenius S; Thor H; Jernström B
    Ciba Found Symp; 1980; 76():25-42. PubMed ID: 6109599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biliary excretion of novel pneumotoxic metabolites of the pyrrolizidine alkaloid, monocrotaline.
    Lafranconi WM; Ohkuma S; Huxtable RJ
    Toxicon; 1985; 23(6):983-92. PubMed ID: 3938082
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The toxic effects in rats of some synthanecine carbamate and phosphate esters analogous to hepatotoxic pyrrolizidine alkaloids.
    Driver HE; Mattocks AR
    Chem Biol Interact; 1984 Sep; 51(2):201-18. PubMed ID: 6467455
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.
    Tang J; Akao T; Nakamura N; Wang ZT; Takagawa K; Sasahara M; Hattori M
    Drug Metab Dispos; 2007 Oct; 35(10):1832-9. PubMed ID: 17639025
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of 3-methylcholanthrene on covalent binding and toxicity of 4-ipomeanol in inducible and non-inducible (B6D2) mice.
    Jones RB; Statham CN; Boyd MR
    Toxicology; 1983; 28(3):183-91. PubMed ID: 6636204
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationship between in vitro metabolism of pyrrolizidine alkaloids and extrahepatic toxicity in vivo.
    Huxtable RJ; Wild SL
    Proc West Pharmacol Soc; 1994; 37():109-11. PubMed ID: 7984636
    [No Abstract]   [Full Text] [Related]  

  • 18. Bromobenzene-glutathione excretion into bile reflects toxic activation of bromobenzene in rats.
    Madhu C; Klaassen CD
    Toxicol Lett; 1992 Apr; 60(2):227-36. PubMed ID: 1570637
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro metabolism of L-696,229, an HIV-1 reverse transcriptase inhibitor in rats and humans. Hepatic and extrahepatic metabolism and identification of enzymes involved in the hepatic metabolism.
    Prueksaritanont T; Dwyer LM; Balani SK; Theoharides AD
    Drug Metab Dispos; 1994; 22(2):281-8. PubMed ID: 7516854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The influence of some hepatic enzyme inducers and inhibitors on extrahepatic drug metabolism.
    Lake BG; Hopkins R; Chakraborty J; Bridges JW; Parke DV
    Drug Metab Dispos; 1973; 1(1):342-9. PubMed ID: 4149403
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.