BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 6818720)

  • 1. Hydrolysis and hepatotoxicity of retronecine diesters.
    Mattocks AR
    Toxicol Lett; 1982 Nov; 14(1-2):111-6. PubMed ID: 6818720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyrrolic and N-oxide metabolites formed from pyrrolizidine alkaloids by hepatic microsomes in vitro: relevance to in vivo hepatotoxicity.
    Mattocks AR; Bird I
    Chem Biol Interact; 1983 Feb; 43(2):209-22. PubMed ID: 6825198
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relation of structural features to pyrrolic metabolites in livers of rats given pyrrolizidine alkaloids and derivatives.
    Mattocks AR
    Chem Biol Interact; 1981 Jun; 35(3):301-10. PubMed ID: 7226276
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepato- and pneumotoxicity of pyrrolizidine alkaloids and derivatives in relation to molecular structure.
    Culvenor CC; Edgar JA; Jago MV; Qutteridge A; Peterson JE; Smith LW
    Chem Biol Interact; 1976 Mar; 12(3-4):299-324. PubMed ID: 1253333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolic activation of retronecine and retronecine N-oxide - formation of DHP-derived DNA adducts.
    Yan J; Xia Q; Chou MW; Fu PP
    Toxicol Ind Health; 2008 Apr; 24(3):181-8. PubMed ID: 18842697
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis.
    Ruan J; Yang M; Fu P; Ye Y; Lin G
    Chem Res Toxicol; 2014 Jun; 27(6):1030-9. PubMed ID: 24836403
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A competitive enzyme-linked immunosorbent assay (ELISA) to detect retronecine and monocrotaline in vitro.
    Bober MA; Milco LA; Miller RB; Mount M; Wicks B; Kurth MJ
    Toxicon; 1989; 27(9):1059-64. PubMed ID: 2508272
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro metabolism of isoline, a pyrrolizidine alkaloid from Ligularia duciformis, by rodent liver microsomal esterase and enhanced hepatotoxicity by esterase inhibitors.
    Tang J; Akao T; Nakamura N; Wang ZT; Takagawa K; Sasahara M; Hattori M
    Drug Metab Dispos; 2007 Oct; 35(10):1832-9. PubMed ID: 17639025
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detection of sulphur-conjugated pyrrolic metabolites in blood and fresh or fixed liver tissue from rats given a variety of toxic pyrrolizidine alkaloids.
    Mattocks AR; Jukes R
    Toxicol Lett; 1992 Oct; 63(1):47-55. PubMed ID: 1412522
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The toxic effects in rats of some synthanecine carbamate and phosphate esters analogous to hepatotoxic pyrrolizidine alkaloids.
    Driver HE; Mattocks AR
    Chem Biol Interact; 1984 Sep; 51(2):201-18. PubMed ID: 6467455
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Microsomal metabolism of pyrrolizidine alkaloids from Senecio jacobaea. Isolation and quantification of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine and N-oxides by high performance liquid chromatography.
    Ramsdell HS; Kedzierski B; Buhler DR
    Drug Metab Dispos; 1987; 15(1):32-6. PubMed ID: 2881756
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genotoxicity of a variety of pyrrolizidine alkaloids in the hepatocyte primary culture-DNA repair test using rat, mouse, and hamster hepatocytes.
    Mori H; Sugie S; Yoshimi N; Asada Y; Furuya T; Williams GM
    Cancer Res; 1985 Jul; 45(7):3125-9. PubMed ID: 4005849
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism, cytotoxicity, and genotoxicity of the pyrrolizidine alkaloid senecionine in primary cultures of rat hepatocytes.
    Green CE; Segall JH; Byard JL
    Toxicol Appl Pharmacol; 1981 Sep; 60(2):176-85. PubMed ID: 7281182
    [No Abstract]   [Full Text] [Related]  

  • 14. Comparative Study of Hepatotoxicity of Pyrrolizidine Alkaloids Retrorsine and Monocrotaline.
    Yang X; Li W; Sun Y; Guo X; Huang W; Peng Y; Zheng J
    Chem Res Toxicol; 2017 Feb; 30(2):532-539. PubMed ID: 28095673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.
    Xia Q; Yan J; Chou MW; Fu PP
    Toxicol Lett; 2008 May; 178(2):77-82. PubMed ID: 18395999
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP; Yan J; Fu PP; Chou MW
    Toxicol Lett; 2005 Mar; 155(3):411-20. PubMed ID: 15649625
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Editor's Highlight: Identification of Any Structure-Specific Hepatotoxic Potential of Different Pyrrolizidine Alkaloids Using Random Forests and Artificial Neural Networks.
    Schöning V; Hammann F; Peinl M; Drewe J
    Toxicol Sci; 2017 Dec; 160(2):361-370. PubMed ID: 28973379
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disenecioyl dehydroretronecine--synthesis and acute hepatic toxicity of a pyrrolizidine alkaloid pyrrole analog.
    Shumaker RC; Seymour JL; Allen JR
    Res Commun Chem Pathol Pharmacol; 1976 May; 14(1):53-61. PubMed ID: 935654
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Dose-related inhibition of the drug-metabolizing enzymes of rat liver by the pyrrolizidine alkaloid, monocrotaline.
    Dalvi RR
    J Pharm Pharmacol; 1987 May; 39(5):386-8. PubMed ID: 2886588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids.
    Luckert C; Braeuning A; Lampen A; Hessel-Pras S
    Chem Biol Interact; 2018 May; 288():38-48. PubMed ID: 29665350
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.