138 related articles for article (PubMed ID: 6827487)
1. Normal and retrograde perfusion to probe the zonal distribution of sulfation and glucuronidation activities of harmol in the perfused rat liver preparation.
Pang KS; Koster H; Halsema IC; Scholtens E; Mulder GJ; Stillwell RN
J Pharmacol Exp Ther; 1983 Mar; 224(3):647-53. PubMed ID: 6827487
[TBL] [Abstract][Full Text] [Related]
2. Kinetics of sulfation in the rat in vivo and in the perfused rat liver.
Mulder GJ
Fed Proc; 1986 Jul; 45(8):2229-34. PubMed ID: 3087784
[TBL] [Abstract][Full Text] [Related]
3. Effects of retrograde flow on measured blood volume, Disse space, intracellular water space and drug extraction in the perfused rat liver: characterization by the multiple indicator dilution technique.
Xu N; Chow A; Goresky CA; Pang KS
J Pharmacol Exp Ther; 1990 Sep; 254(3):914-25. PubMed ID: 2395120
[TBL] [Abstract][Full Text] [Related]
4. Selective inhibition of glucuronidation by 2,2,2-triphenylethyl-UDP in isolated rat hepatocytes: conjugation of harmol, 3,3',5-triiodothyronine, and N-hydroxy-2-acetylaminofluorene.
Noort D; Meijer EA; Visser TJ; Meerman JH; Van der Marel GA; Van Boom JH; Mulder GJ
Mol Pharmacol; 1991 Aug; 40(2):316-20. PubMed ID: 1908549
[TBL] [Abstract][Full Text] [Related]
5. Competing pathways in drug metabolism. I. Effect of input concentration on the conjugation of gentisamide in the once-through in situ perfused rat liver preparation.
Morris ME; Yuen V; Tang BK; Pang KS
J Pharmacol Exp Ther; 1988 May; 245(2):614-24. PubMed ID: 3367309
[TBL] [Abstract][Full Text] [Related]
6. Combined hepatic arterial-portal venous and hepatic arterial-hepatic venous perfusions to probe the abundance of drug metabolizing activities: perihepatic venous O-deethylation activity for phenacetin and periportal sulfation activity for acetaminophen in the once-through rat liver preparation.
Pang KS; Cherry WF; Accaputo J; Schwab AJ; Goresky CA
J Pharmacol Exp Ther; 1988 Nov; 247(2):690-700. PubMed ID: 3183964
[TBL] [Abstract][Full Text] [Related]
7. First-pass metabolism of gentisamide: influence of intestinal metabolism on hepatic formation of conjugates. Studies in the once-through vascularly perfused rat intestine-liver preparation.
Hirayama H; Pang KS
Drug Metab Dispos; 1990; 18(5):580-7. PubMed ID: 1981705
[TBL] [Abstract][Full Text] [Related]
8. Hypoxia impairs conjugation and elimination of harmol in the isolated perfused rat liver.
Angus PW; Mihaly GW; Morgan DJ; Smallwood RA
J Pharmacol Exp Ther; 1987 Mar; 240(3):931-6. PubMed ID: 3559985
[TBL] [Abstract][Full Text] [Related]
9. Biliary and urinary excretion of drug conjugates: effect of diuresis and choleresis on excretion of harmol sulphate and harmol glucuronide in the rat.
Jorritsma J; Meerman JH; Vonk RJ; Mulder GJ
Xenobiotica; 1979 Apr; 9(4):247-52. PubMed ID: 483860
[TBL] [Abstract][Full Text] [Related]
10. Sequential metabolism of salicylamide exclusively to gentisamide 5-glucuronide and not gentisamide sulfate conjugates in single-pass in situ perfused rat liver.
Xu X; Tang BK; Pang KS
J Pharmacol Exp Ther; 1990 Jun; 253(3):965-73. PubMed ID: 2359032
[TBL] [Abstract][Full Text] [Related]
11. Synergistic effects of hypoxia and fasting on harmol elimination in the isolated perfused rat liver.
Angus PW; Mihaly GW; Morgan DJ; Smallwood RA
Biochem Pharmacol; 1988 Apr; 37(7):1207-12. PubMed ID: 3355595
[TBL] [Abstract][Full Text] [Related]
12. Hepatic modeling of metabolite kinetics in sequential and parallel pathways: salicylamide and gentisamide metabolism in perfused rat liver.
Xu X; Pang KS
J Pharmacokinet Biopharm; 1989 Dec; 17(6):645-71. PubMed ID: 2635738
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of sulfation of phenols in vivo by 2,6-dichloro-4-nitrophenol: selectivity of its action in relation to other conjugations in the rat in vivo.
Koster H; Scholtens E; Mulder GJ
Med Biol; 1979 Oct; 57(5):340-4. PubMed ID: 522521
[TBL] [Abstract][Full Text] [Related]
14. Heterogeneous distribution of the conjugation activity of acetaminophen and p-nitrophenol in isolated rat liver cells.
Araya H; Mizuma T; Horie T; Hayashi M; Awazu S
J Pharmacobiodyn; 1986 Feb; 9(2):218-22. PubMed ID: 3712218
[TBL] [Abstract][Full Text] [Related]
15. Competing pathways in drug metabolism. II. An identical, anterior enzymic distribution for 2- and 5-sulfoconjugation and a posterior localization for 5-glucuronidation of gentisamide in the rat liver.
Morris ME; Yuen V; Pang KS
J Pharmacokinet Biopharm; 1988 Dec; 16(6):633-56. PubMed ID: 3251033
[TBL] [Abstract][Full Text] [Related]
16. Intestinal biotransformation of harmol and 1-naphthol in the rat. Further evidence of dose-dependent phase-II conjugation in situ.
Goon D; Klaassen CD
Drug Metab Dispos; 1991; 19(2):340-7. PubMed ID: 1676634
[TBL] [Abstract][Full Text] [Related]
17. Fasting increases the sensitivity of hepatic harmol glucuronidation to hypoxia.
Elliott SL; Morgan DJ; Smallwood RA
Biochem Pharmacol; 1992 Nov; 44(9):1887-90. PubMed ID: 1449541
[TBL] [Abstract][Full Text] [Related]
18. First-pass metabolism of salicylamide. Studies in the once-through vascularly perfused rat intestine-liver preparation.
Xu X; Hirayama H; Pang KS
Drug Metab Dispos; 1989; 17(5):556-63. PubMed ID: 2573500
[TBL] [Abstract][Full Text] [Related]
19. Effect of 3-methylcholanthrene pretreatment on glucuronidation and sulfation in perfused rat liver.
Hamada N; Gessner T
Drug Metab Dispos; 1975; 3(5):407-16. PubMed ID: 241622
[TBL] [Abstract][Full Text] [Related]
20. Effect of glutathione depletion on sulfate activation and sulfate ester formation in rats.
Gregus Z; White C; Howell S; Klaassen CD
Biochem Pharmacol; 1988 Nov; 37(22):4307-12. PubMed ID: 3196355
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]