243 related articles for article (PubMed ID: 688246)
1. Antitumor properties of a new folate analog, 10-deaza-aminopterin, in mice.
Sirotnak FM; DeGraw JI; Moccio DM; Dorick DM
Cancer Treat Rep; 1978 Jul; 62(7):1047-52. PubMed ID: 688246
[TBL] [Abstract][Full Text] [Related]
2. Combination chemotherapy with a new folate analog: activity of 10-ethyl-10-deaza-aminopterin compared to methotrexate with 5-fluorouracil and alkylating agents against advanced metastatic disease in murine tumor models.
Schmid FA; Sirotnak FM; Otter GM; DeGraw JI
Cancer Treat Rep; 1987; 71(7-8):727-32. PubMed ID: 3607784
[TBL] [Abstract][Full Text] [Related]
3. New folate analogs of the 10-deaza-aminopterin series: markedly increased antitumor activity of the 10-ethyl analog compared to the parent compound and methotrexate against some human tumor xenografts in nude mice.
Schmid FA; Sirotnak FM; Otter GM; DeGraw JI
Cancer Treat Rep; 1985 May; 69(5):551-3. PubMed ID: 4005878
[TBL] [Abstract][Full Text] [Related]
4. New folate analogs of the 10-deaza-aminopterin series. Further evidence for markedly increased antitumor efficacy compared with methotrexate in ascitic and solid murine tumor models.
Sirotnak FM; DeGraw JI; Schmid FA; Goutas LJ; Moccio DM
Cancer Chemother Pharmacol; 1984; 12(1):26-30. PubMed ID: 6690070
[TBL] [Abstract][Full Text] [Related]
5. Biochemical and pharmacologic properties of a new folate analog, 10-deaza-aminopterin, in mice.
Sirotnak FM; DeGraw JI; Chello PL; Moccio DM; Dorick DM
Cancer Treat Rep; 1982 Feb; 66(2):351-8. PubMed ID: 7055818
[No Abstract] [Full Text] [Related]
6. 10-Ethyl-10-deaza-aminopterin: structural design and biochemical, pharmacologic, and antitumor properties.
Sirotnak FM; Schmid FA; Samuels LL; DeGraw JI
NCI Monogr; 1987; (5):127-31. PubMed ID: 2448650
[TBL] [Abstract][Full Text] [Related]
7. Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro.
Samuels LL; Moccio DM; Sirotnak FM
Cancer Res; 1985 Apr; 45(4):1488-95. PubMed ID: 3978616
[TBL] [Abstract][Full Text] [Related]
8. Further evidence for a basis of selective activity and relative responsiveness during antifolate therapy of murine tumors.
Sirotnak FM; Donsback RC
Cancer Res; 1975 Jul; 35(7):1737-44. PubMed ID: 1169115
[TBL] [Abstract][Full Text] [Related]
9. [Tomizine--a new inhibitor of folate metabolism enzymes possessing an antitumor activity].
Sokolova AS; Riabokon' NA; Ershova IuA; Andreeva NA; Nemeriuk MP
Vopr Onkol; 1975; 21(11):45-50. PubMed ID: 174306
[TBL] [Abstract][Full Text] [Related]
10. Structural design, biochemical properties, and evidence for improved therapeutic activity of 5-alkyl derivatives of 5-deazaaminopterin and 5-deazamethotrexate compared to methotrexate in murine tumor models.
Sirotnak FM; Schmid FA; Otter GM; Piper JR; Montgomery JA
Cancer Res; 1988 Oct; 48(20):5686-91. PubMed ID: 3167828
[TBL] [Abstract][Full Text] [Related]
11. Markedly improved efficacy of edatrexate compared to methotrexate in a high-dose regimen with leucovorin rescue against metastatic murine solid tumors.
Sirotnak FM; Otter GM; Schmid FA
Cancer Res; 1993 Feb; 53(3):587-91. PubMed ID: 8425192
[TBL] [Abstract][Full Text] [Related]
12. Differing specificities for 4-aminofolate analogues of folylpolyglutamyl synthetase from tumors and proliferative intestinal epithelium of the mouse with significance for selective antitumor action.
Rumberger BG; Barrueco JR; Sirotnak FM
Cancer Res; 1990 Aug; 50(15):4639-43. PubMed ID: 2369741
[TBL] [Abstract][Full Text] [Related]
13. Optimization of high-dose methotrexate with leucovorin rescue therapy in the L1210 leukemia and sarcoma 180 murine tumor models.
Sirotnak FM; Moccio DM; Dorick DM
Cancer Res; 1978 Feb; 38(2):345-53. PubMed ID: 304375
[TBL] [Abstract][Full Text] [Related]
14. New folate analogs of the 10-deaza-aminopterin series. Basis for structural design and biochemical and pharmacologic properties.
Sirotnak FM; DeGraw JI; Moccio DM; Samuels LL; Goutas LJ
Cancer Chemother Pharmacol; 1984; 12(1):18-25. PubMed ID: 6690069
[TBL] [Abstract][Full Text] [Related]
15. Cytotoxicity, uptake, polyglutamate formation, and antileukemic effects of 8-deaza analogues of methotrexate and aminopterin in mice.
Kuehl M; Brixner DI; Broom AD; Avery TL; Blakley RL
Cancer Res; 1988 Mar; 48(6):1481-8. PubMed ID: 2449950
[TBL] [Abstract][Full Text] [Related]
16. Activity of the folate analog 10-ethyl, 10-deaza-aminopterin (10-EdAM) against human head and neck cancer xenografts.
Brown DH; Braakhuis BJ; van Dongen GA; van Walsum M; Bagnay M; Snow GB
Anticancer Res; 1989; 9(6):1549-52. PubMed ID: 2627109
[TBL] [Abstract][Full Text] [Related]
17. A new analogue of 10-deazaaminopterin with markedly enhanced curative effects against human tumor xenografts in mice.
Sirotnak FM; DeGraw JI; Colwell WT; Piper JR
Cancer Chemother Pharmacol; 1998; 42(4):313-8. PubMed ID: 9744777
[TBL] [Abstract][Full Text] [Related]
18. Intracavitary therapy of murine ovarian cancer with cis-diamminedichloroplatinum(II) and 10-ethyl-10-deazaaminopterin incorporating systemic leucovorin protection.
Sirotnak FM; Schmid FA; DeGraw JI
Cancer Res; 1989 Jun; 49(11):2890-3. PubMed ID: 2785847
[TBL] [Abstract][Full Text] [Related]
19. Comparison of 5-fluorouracil and ftorafur. II. Therapeutic response and development of resistance in murine tumors.
Garibjanian BT; Johnson RK; Kline I; Vadlamudi S; Gang M; Venditti JM; Goldin A
Cancer Treat Rep; 1976 Sep; 60(9):1347-61. PubMed ID: 797450
[TBL] [Abstract][Full Text] [Related]
20. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]