BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

146 related articles for article (PubMed ID: 6929188)

  • 1. Effects of methotrexate esters and other lipophilic antifolates on methotrexate-resistant human leukemic lymphoblasts.
    Rosowsky A; Lazarus H; Yuan GC; Beltz WR; Mangini L; Abelson HT; Modest EJ; Frei E
    Biochem Pharmacol; 1980 Feb; 29(4):648-52. PubMed ID: 6929188
    [No Abstract]   [Full Text] [Related]  

  • 2. Establishment of methotrexate-resistant human acute lymphoblastic leukemia cells in culture and effects of folate antagonists.
    Ohnoshi T; Ohnuma T; Takahashi I; Scanlon K; Kamen BA; Holland JF
    Cancer Res; 1982 May; 42(5):1655-60. PubMed ID: 6978176
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical pharmacology of lipophilic diaminopyrimidine antifolates in mouse and human cells in vitro.
    Greco WR; Hakala MT
    Mol Pharmacol; 1980 Nov; 18(3):521-8. PubMed ID: 6970329
    [No Abstract]   [Full Text] [Related]  

  • 4. Effects of methotrexate and other antifolates on the growth and dihydrofolate reductase activity of Leishmania promastigotes.
    Scott DA; Coombs GH; Sanderson BE
    Biochem Pharmacol; 1987 Jun; 36(12):2043-5. PubMed ID: 3593407
    [No Abstract]   [Full Text] [Related]  

  • 5. Quinazoline antifolates as inhibitors of dihydrofolate reductase from human leukemia cells.
    Johns DG; Capizzi RL; Nahas A; Cashmore AR; Bertino JR
    Biochem Pharmacol; 1970 Apr; 19(4):1528-33. PubMed ID: 5284463
    [No Abstract]   [Full Text] [Related]  

  • 6. Methods and mechanisms for the development of MTX resistance in human lymphoid cells.
    Alam A; Geddes AJ; North AC
    Int J Cancer; 1983 Jan; 31(1):45-50. PubMed ID: 6832848
    [No Abstract]   [Full Text] [Related]  

  • 7. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells.
    Sharma RC; Assaraf YG; Schimke RT
    Cancer Res; 1991 Jun; 51(11):2949-59. PubMed ID: 1674447
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Drosophila dihydrofolate reductase mutations confer antifolate resistance to mammalian cells.
    Affleck JG; Al-Batayneh KM; Neumann K; Cole SP; Walker VK
    Eur J Pharmacol; 2006 Jan; 529(1-3):71-8. PubMed ID: 16325803
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mechanisms of sensitivity and natural resistance to antifolates in a methylcholanthrene-induced rat sarcoma.
    Li WW; Lin JT; Schweitzer BI; Bertino JR
    Mol Pharmacol; 1991 Nov; 40(5):854-8. PubMed ID: 1719370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H; Niethammer D; Jackson RC
    Cancer Res; 1983 Nov; 43(11):5286-92. PubMed ID: 6225514
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
    Albrecht AM; Biedler JL; Hutchison DJ
    Cancer Res; 1972 Jul; 32(7):1539-46. PubMed ID: 4402276
    [No Abstract]   [Full Text] [Related]  

  • 12. Drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant Chinese hamster cells in vitro.
    Biedler JL; Albrecht AM; Hutchison DJ; Spengler BA
    Cancer Res; 1972 Jan; 32(1):153-61. PubMed ID: 5007683
    [No Abstract]   [Full Text] [Related]  

  • 13. Membrane transport of antifolates as a critical determinant of drug cytotoxicity.
    Goldman ID
    Adv Exp Med Biol; 1977; 84():85-113. PubMed ID: 331908
    [No Abstract]   [Full Text] [Related]  

  • 14. Elevation of dihydrofolate reductase, thymidylate synthetase, and thymidine kinase in cultured mammalian cells after exposure to folate antagonists.
    Chello PL; McQueen CA; DeAngelis LM; Bertino JR
    Cancer Res; 1976 Jul; 36(7 PT 1):2442-9. PubMed ID: 1277151
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 2-tier bacterial and in vitro selection of active and methotrexate-resistant variants of human dihydrofolate reductase.
    Fossati E; Volpato JP; Poulin L; Guerrero V; Dugas DA; Pelletier JN
    J Biomol Screen; 2008 Jul; 13(6):504-14. PubMed ID: 18566481
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison of the effects of methotrexate and pyrimethamine on L5178Y lymphoblasts in cell culture.
    Goldie JH; Furness ME; Price LA
    Eur J Cancer (1965); 1973 Oct; 9(10):709-15. PubMed ID: 4529729
    [No Abstract]   [Full Text] [Related]  

  • 17. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
    Chen G; Wright JE; Rosowsky A
    Mol Pharmacol; 1995 Oct; 48(4):758-65. PubMed ID: 7476904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of methotrexate transport deficiency in mammalian cells using fluoresceinated methotrexate and flow cytometry.
    Assaraf YG; Schimke RT
    Proc Natl Acad Sci U S A; 1987 Oct; 84(20):7154-8. PubMed ID: 3478688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transport of a fluorescent antifolate by methotrexate-sensitive and methotrexate-resistant human leukemic lymphoblasts.
    Rosowsky A; Wright JE; Cucchi CA; Boeheim K; Frei E
    Biochem Pharmacol; 1986 Jan; 35(2):356-60. PubMed ID: 3942605
    [No Abstract]   [Full Text] [Related]  

  • 20. Flow cytometric characterization of antifolate resistance in cultured mammalian cells using fluoresceinated methotrexate and daunorubicin.
    Sherwood SW; Assaraf YG; Molina A; Schimke RT
    Cancer Res; 1990 Aug; 50(16):4946-50. PubMed ID: 2143099
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.