These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

308 related articles for article (PubMed ID: 6935452)

  • 1. Activity of free and carrier-bound methotrexate against transport-deficient and high dihydrofolate dehydrogenase-containing methotrexate-resistant L1210 cells.
    Chu BC; Fan CC; Howell SB
    J Natl Cancer Inst; 1981 Jan; 66(1):121-4. PubMed ID: 6935452
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The mechanism of transport of the multitargeted antifolate (MTA) and its cross-resistance pattern in cells with markedly impaired transport of methotrexate.
    Zhao R; Babani S; Gao F; Liu L; Goldman ID
    Clin Cancer Res; 2000 Sep; 6(9):3687-95. PubMed ID: 10999762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biochemical correlates of responsiveness and collateral sensitivity of some methotrexate-resistant murine tumors to the lipophilic antifolate, metoprine.
    Sirotnak FM; Moccio DM; Goutas LJ; Kelleher LE; Montgomery JA
    Cancer Res; 1982 Mar; 42(3):924-8. PubMed ID: 7059991
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.
    Sirotnak FM; Moccio DM; Kelleher LE; Goutas LJ
    Cancer Res; 1981 Nov; 41(11 Pt 1):4447-52. PubMed ID: 7306968
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Establishment of methotrexate-resistant human acute lymphoblastic leukemia cells in culture and effects of folate antagonists.
    Ohnoshi T; Ohnuma T; Takahashi I; Scanlon K; Kamen BA; Holland JF
    Cancer Res; 1982 May; 42(5):1655-60. PubMed ID: 6978176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A comparison of dihydrofolate reductase activity in intact leukemia cells and squamous cell carcinoma.
    FitzGerald GB; Wick MM
    Anticancer Drug Des; 1989 Jun; 4(1):79-87. PubMed ID: 2757754
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transport of the antitumor antibiotic Cl-920 into L1210 leukemia cells by the reduced folate carrier system.
    Fry DW; Besserer JA; Boritzki TJ
    Cancer Res; 1984 Aug; 44(8):3366-70. PubMed ID: 6547636
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacological and therapeutic properties of carrier bound methotrexate against tumor confined to a third space body compartment.
    Chu BC; Howell SB
    J Pharmacol Exp Ther; 1981 Nov; 219(2):389-93. PubMed ID: 6974776
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo.
    Mauritz R; Peters GJ; Kathmann I; Teshale H; Noordhuis P; Comijn EM; Pinedo HM; Jansen G
    Cancer Chemother Pharmacol; 2008 Nov; 62(6):937-48. PubMed ID: 18283461
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sensitivity to 5,10-dideazatetrahydrofolate is fully conserved in a murine leukemia cell line highly resistant to methotrexate due to impaired transport mediated by the reduced folate carrier.
    Zhao R; Gao F; Babani S; Goldman ID
    Clin Cancer Res; 2000 Aug; 6(8):3304-11. PubMed ID: 10955817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Biochemical studies on PT523, a potent nonpolyglutamatable antifolate, in cultured cells.
    Rhee MS; Galivan J; Wright JE; Rosowsky A
    Mol Pharmacol; 1994 Apr; 45(4):783-91. PubMed ID: 7514264
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regiospecific gamma-conjugation of methotrexate to poly(L-lysine). Chemical and biological studies.
    Rosowsky A; Forsch RA; Galivan J; Susten SS; Freisheim JH
    Mol Pharmacol; 1985 Jan; 27(1):141-7. PubMed ID: 3965926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The role of methotrexate and dihydrofolate polyglutamates in the enhancement of fluorouracil action by methotrexate.
    Fernandes DJ; Moroson BA; Bertino JR
    Cancer Treat Rep; 1981; 65 Suppl 1():29-35. PubMed ID: 6173121
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Preferential selection during therapy in vivo by edatrexate compared to methotrexate of resistant L1210 cell variants with decreased folylpolyglutamate synthetase activity.
    Rumberger BG; Schmid FA; Otter GM; Sirotnak FM
    Cancer Commun; 1990; 2(9):305-10. PubMed ID: 2206778
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical and pharmacologic rationale for high-dose methotrexate.
    Jolivet J
    NCI Monogr; 1987; (5):61-5. PubMed ID: 2448656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Investigations on the mechanisms of methotrexate resistance in a cisplatin-resistant L1210 murine leukemia cell subline.
    Wroblewski DH; Bhushan A; Xuan Y; Brinton BT; Tritton TR; Hacker MP
    Cancer Chemother Pharmacol; 1996; 37(4):337-42. PubMed ID: 8548879
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A direct ligand-binding radioassay for the measurement of methotrexate in tissues and biological fluids.
    Arons E; Rothenberg SP; Costa MD; Fischer C; Iqbal MP
    Cancer Res; 1975 Aug; 35(8):2033-8. PubMed ID: 807320
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Establishment of dihydrofolate reductase-increased human cell lines and relationship between dihydrofolate reductase levels and gene copy.
    Domin BA; Grill SP; Cheng Y
    Cancer Res; 1983 May; 43(5):2155-8. PubMed ID: 6831441
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.