BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

75 related articles for article (PubMed ID: 6956488)

  • 1. Effects of 5,8-dideazaisofolic acid (IAHQ) on human tumor cells in culture and on normal and tumor-bearing hamsters.
    Tsang KY; Hynes JB; Fudenberg HH
    Chemotherapy; 1982; 28(4):276-82. PubMed ID: 6956488
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Improved synthesis and antitumor evaluation of 5,8-dideazaisofolic acid and closely related analogues.
    Hynes JB; Yang YC; McGill JE; Harmon SJ; Washtien WL
    J Med Chem; 1984 Feb; 27(2):232-5. PubMed ID: 6694171
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Isoprinosine as an immunopotentiator in an animal model of human osteosarcoma.
    Tsang KY; Fudenberg HH
    Int J Immunopharmacol; 1981; 3(4):383-9. PubMed ID: 6174468
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of 5,8-dideazaisopteroylglutamate (IAHQ) on L1210 leukemia in mice when given alone and in combination with methotrexate, probenecid, or verapamil.
    Hynes JB; Smith AB; Gale GR
    Cancer Chemother Pharmacol; 1986; 18(3):231-4. PubMed ID: 3802378
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Uptake and metabolism of 5,8-dideazaisofolic acid in human colon carcinoma cells.
    Sobrero AF; McGuire JJ; Bertino JR
    Biochem Pharmacol; 1988 Mar; 37(6):997-1001. PubMed ID: 2451526
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of 5,8-dideazaisopteroylglutamate and its possible tri-gamma-glutamyl metabolite (5,8-dideazaisoPteGlu3) on colon adenocarcinoma, and the folate dependent enzymes thymidylate synthase and dihydrofolate reductase.
    Fernandes DJ; Cardenas RM; Bertino JR; Hynes JB
    Adv Exp Med Biol; 1983; 163():341-57. PubMed ID: 6688493
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and biological evaluation of analogues of 5,8-dideazaisofolic acid (IAHQ) modified at positions 2, 4 and 9.
    Hynes JB; Hagan RL; Shane B; Freisheim JH
    Adv Exp Med Biol; 1993; 338():417-20. PubMed ID: 8304148
    [No Abstract]   [Full Text] [Related]  

  • 8. Effects of three new folate antagonists on human breast adenocarcinoma cells in vitro and on immune responses in vivo.
    Tsang KY; Hynes JB; Fudenberg HH; Pan JF
    Chemotherapy; 1984; 30(1):61-8. PubMed ID: 6692721
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
    Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM
    Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N10-propargyl-5,8-dideazafolic acid (CB3717): inhibitory effects on human leukemia cell lines resistant to methotrexate or trimetrexate.
    Takemura Y; Ohnuma T
    Mt Sinai J Med; 1992 Oct; 59(5):419-24. PubMed ID: 1435841
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Patterns of cross-resistance to the antifolate drugs trimetrexate, metoprine, homofolate, and CB3717 in human lymphoma and osteosarcoma cells resistant to methotrexate.
    Diddens H; Niethammer D; Jackson RC
    Cancer Res; 1983 Nov; 43(11):5286-92. PubMed ID: 6225514
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of sensitivity and natural resistance to antifolates in a methylcholanthrene-induced rat sarcoma.
    Li WW; Lin JT; Schweitzer BI; Bertino JR
    Mol Pharmacol; 1991 Nov; 40(5):854-8. PubMed ID: 1719370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanism of action of 5,8-dideazaisofolic acid and other quinazoline antifols in human colon carcinoma cells.
    McGuire JJ; Sobrero AF; Hynes JB; Bertino JR
    Cancer Res; 1987 Nov; 47(22):5975-81. PubMed ID: 3664501
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Resistance of human tumor cell lines to antifolates.
    Diddens H; Niethammer D; Jackson RC
    Cancer Treat Rev; 1984 Mar; 11 Suppl A():37-41. PubMed ID: 6234060
    [No Abstract]   [Full Text] [Related]  

  • 15. Pemetrexed, a multitargeted antifolate drug, demonstrates lower efficacy in comparison to methotrexate against osteosarcoma cell lines.
    Bodmer N; Walters DK; Fuchs B
    Pediatr Blood Cancer; 2008 Apr; 50(4):905-8. PubMed ID: 17534933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cytotoxic effects of folate antagonists against methotrexate-resistant human leukemic lymphoblast CCRF-CEM cell lines.
    Mini E; Moroson BA; Franco CT; Bertino JR
    Cancer Res; 1985 Jan; 45(1):325-30. PubMed ID: 3855284
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Two different species of dihydrofolate reductase in mammalian cells differentially resistant to amethopterin and methasquin.
    Albrecht AM; Biedler JL; Hutchison DJ
    Cancer Res; 1972 Jul; 32(7):1539-46. PubMed ID: 4402276
    [No Abstract]   [Full Text] [Related]  

  • 18. Drug response, dihydrofolate reductase, and cytogenetics of amethopterin-resistant Chinese hamster cells in vitro.
    Biedler JL; Albrecht AM; Hutchison DJ; Spengler BA
    Cancer Res; 1972 Jan; 32(1):153-61. PubMed ID: 5007683
    [No Abstract]   [Full Text] [Related]  

  • 19. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Westerhof GR; Rijnboutt S; Schornagel JH; Pinedo HM; Peters GJ; Jansen G
    Cancer Res; 1995 Sep; 55(17):3795-802. PubMed ID: 7641196
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endogenous thymidine and hypoxanthine are a source of error in evaluating methotrexate cytotoxicity by clonogenic assays using undialyzed fetal bovine serum.
    Sobrero AF; Bertino JR
    Int J Cell Cloning; 1986 Jan; 4(1):51-62. PubMed ID: 2936838
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.