BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 6961444)

  • 1. Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.
    Chin DJ; Luskey KL; Faust JR; MacDonald RJ; Brown MS; Goldstein JL
    Proc Natl Acad Sci U S A; 1982 Dec; 79(24):7704-8. PubMed ID: 6961444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of a cholesterol-regulated 53,000-dalton cytosolic protein in UT-1 cells and cloning of its cDNA.
    Luskey KL; Chin DJ; MacDonald RJ; Liscum L; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 1982 Oct; 79(20):6210-4. PubMed ID: 6959111
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amplification of the gene for 3-hydroxy-3-methylglutaryl coenzyme A reductase, but not for the 53-kDa protein, in UT-1 cells.
    Luskey KL; Faust JR; Chin DJ; Brown MS; Goldstein JL
    J Biol Chem; 1983 Jul; 258(13):8462-9. PubMed ID: 6863296
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase and its mRNA in rat liver as studied with a monoclonal antibody and a cDNA probe.
    Liscum L; Luskey KL; Chin DJ; Ho YK; Goldstein JL; Brown MS
    J Biol Chem; 1983 Jul; 258(13):8450-5. PubMed ID: 6688077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.
    Chin DJ; Gil G; Faust JR; Goldstein JL; Brown MS; Luskey KL
    Mol Cell Biol; 1985 Apr; 5(4):634-41. PubMed ID: 3838796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Regulation of synthesis and degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase by low density lipoprotein and 25-hydroxycholesterol in UT-1 cells.
    Faust JR; Luskey KL; Chin DJ; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 1982 Sep; 79(17):5205-9. PubMed ID: 6957860
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Chin DJ; Luskey KL; Anderson RG; Faust JR; Goldstein JL; Brown MS
    Proc Natl Acad Sci U S A; 1982 Feb; 79(4):1185-9. PubMed ID: 6951166
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proto oncogene/eukaryotic translation initiation factor (eIF) 4E attenuates mevalonate-mediated regulation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase synthesis.
    Buechler RD; Peffley DM
    Mol Carcinog; 2004 Sep; 41(1):39-53. PubMed ID: 15352124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of mevalonate in regulation of cholesterol synthesis and 3-hydroxy-3-methylglutaryl coenzyme A reductase in cultured cells and their cytoplasts.
    Popják G; Clarke CF; Hadley C; Meenan A
    J Lipid Res; 1985 Jul; 26(7):831-41. PubMed ID: 2411835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multiple mRNAs for 3-hydroxy-3-methylglutaryl coenzyme A reductase determined by multiple transcription initiation sites and intron splicing sites in the 5'-untranslated region.
    Reynolds GA; Goldstein JL; Brown MS
    J Biol Chem; 1985 Aug; 260(18):10369-77. PubMed ID: 2991285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The length of 5'-untranslated leader sequences influences distribution of 3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in polysomes: effects of lovastatin, oxysterols, and mevalonate.
    Gayen AK; Peffley DM
    Arch Biochem Biophys; 1995 Oct; 322(2):475-85. PubMed ID: 7574724
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of porcine granulosa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase by insulin and insulin-like growth factor I: synergism with follicle-stimulating hormone or protein kinase A agonist.
    Maitra A; LaVoie HA; Day RN; Garmey JC; Veldhuis JD
    Endocrinology; 1995 Nov; 136(11):5111-7. PubMed ID: 7588248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleotide sequence of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase, a glycoprotein of endoplasmic reticulum.
    Chin DJ; Gil G; Russell DW; Liscum L; Luskey KL; Basu SK; Okayama H; Berg P; Goldstein JL; Brown MS
    Nature; 1984 Apr 12-18; 308(5960):613-7. PubMed ID: 6546784
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Down-regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels and synthesis in syrian hamster C100 cells by the oxidosqualene cyclase inhibitor [4'-(6-allyl-ethyl-amino-hexyloxy)-2'-fluoro-phenyl]-(4-bromophenyl)-me thanone (Ro 48-8071): comparison to simvastatin.
    Peffley DM; Gayen AK; Morand OH
    Biochem Pharmacol; 1998 Aug; 56(4):439-49. PubMed ID: 9763219
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Radioimmune precipitation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from Chinese hamster fibroblasts. Effect of 25-hydroxycholesterol.
    Sinensky M; Torget R; Edwards PA
    J Biol Chem; 1981 Nov; 256(22):11774-9. PubMed ID: 7298631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 8-bromoadenosine cyclic 3',5'-phosphate rapidly increases 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA in human granulosa cells: role of cellular sterol balance in controlling the response to tropic stimulation.
    Golos TG; Strauss JF
    Biochemistry; 1988 May; 27(9):3503-6. PubMed ID: 3390448
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Splice donor site mutations in the 3-hydroxy-3-methylglutaryl coenzyme A reductase gene cause a deficiency of the endoplasmic reticulum 3-hydroxy-3-methylglutaryl coenzyme A reductase protein in UT2 cells.
    Engfelt WH; Masuda KR; Paton VG; Krisans SK
    J Lipid Res; 1998 Nov; 39(11):2182-91. PubMed ID: 9799804
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of protein synthesis in baby-hamster kidney cells blocks oxysterol-mediated suppression of 3-hydroxy-3-methylglutaryl-CoA reductase mRNA at a post-transcriptional level.
    Choi JW; Lundquist EN; Peffley DM
    Biochem J; 1993 Dec; 296 ( Pt 3)(Pt 3):859-66. PubMed ID: 8280085
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mevalonate regulates polysome distribution and blocks translation-dependent suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA: relationship to translational control.
    Peffley DM; Gayen AK
    Somat Cell Mol Genet; 1995 May; 21(3):189-204. PubMed ID: 7482033
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels by L-triiodothyronine.
    Sample CE; Pendleton LC; Ness GC
    Biochemistry; 1987 Feb; 26(3):727-31. PubMed ID: 3567145
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.