128 related articles for article (PubMed ID: 6993476)
1. Mechanism of inactivation of glutamine amidotransferases by the antitumor drug L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
Tso JY; Bower SG; Zalkin H
J Biol Chem; 1980 Jul; 255(14):6734-8. PubMed ID: 6993476
[TBL] [Abstract][Full Text] [Related]
2. Mechanism for acivicin inactivation of triad glutamine amidotransferases.
Chittur SV; Klem TJ; Shafer CM; Davisson VJ
Biochemistry; 2001 Jan; 40(4):876-87. PubMed ID: 11170408
[TBL] [Abstract][Full Text] [Related]
3. L-[alphaS, 5S]-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): a new amino acid antibiotic with the properties of an antagonist of L-glutamine.
Jayaram HN; Cooney DA; Ryan JA; Neil G; Dion RL; Bono VH
Cancer Chemother Rep; 1975; 59(3):481-91. PubMed ID: 1147
[TBL] [Abstract][Full Text] [Related]
4. In vivo inactivation by acivicin of carbamoyl-phosphate synthetase II in rat hepatoma.
Aoki T; Sebolt J; Weber G
Biochem Pharmacol; 1982 Mar; 31(6):927-32. PubMed ID: 7082374
[TBL] [Abstract][Full Text] [Related]
5. Study of anthranilate synthase function by replacement of cysteine 84 using site-directed mutagenesis.
Paluh JL; Zalkin H; Betsch D; Weith HL
J Biol Chem; 1985 Feb; 260(3):1889-94. PubMed ID: 3881444
[TBL] [Abstract][Full Text] [Related]
6. Evolution of glutamine amidotransferase genes. Nucleotide sequences of the pabA genes from Salmonella typhimurium, Klebsiella aerogenes and Serratia marcescens.
Kaplan JB; Merkel WK; Nichols BP
J Mol Biol; 1985 Jun; 183(3):327-40. PubMed ID: 3894673
[TBL] [Abstract][Full Text] [Related]
7. Studies of the biochemical pharmacology of the fermentation-derived antitumor agent, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
Neil GL; Berger AE; Bhuyan BK; Blowers CL; Kuentzel SL
Adv Enzyme Regul; 1978; 17():375-98. PubMed ID: 757314
[No Abstract] [Full Text] [Related]
8. The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
Allen L; Meck R; Yunis A
Res Commun Chem Pathol Pharmacol; 1980 Jan; 27(1):175-82. PubMed ID: 6102405
[TBL] [Abstract][Full Text] [Related]
9. Biochemical and pharmacological effects of the fermentation-derived antitumor agent, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
Neil GL; Berger AE; McPartland RP; Grindey GB; Bloch A
Cancer Res; 1979 Mar; 39(3):852-6. PubMed ID: 427775
[No Abstract] [Full Text] [Related]
10. The structures of anthranilate synthase of Serratia marcescens crystallized in the presence of (i) its substrates, chorismate and glutamine, and a product, glutamate, and (ii) its end-product inhibitor, L-tryptophan.
Spraggon G; Kim C; Nguyen-Huu X; Yee MC; Yanofsky C; Mills SE
Proc Natl Acad Sci U S A; 2001 May; 98(11):6021-6. PubMed ID: 11371633
[TBL] [Abstract][Full Text] [Related]
11. The inhibition of gamma-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(alpha S, 5S)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
Reed DJ; Ellis WW; Meck RA
Biochem Biophys Res Commun; 1980 Jun; 94(4):1273-7. PubMed ID: 6104962
[No Abstract] [Full Text] [Related]
12. Primary structure of Serratia marcescens anthranilate synthase component II.
Tso JY; Hermodson MA; Zalkin H
J Biol Chem; 1980 Feb; 255(4):1451-7. PubMed ID: 6986371
[TBL] [Abstract][Full Text] [Related]
13. Enhanced effect of an L-glutamine antagonist, L-(alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, by Acinetobacter L-glutaminase-L-asparaginase.
Holcenberg JS
Cancer Treat Rep; 1979 Jun; 63(6):1109-14. PubMed ID: 466650
[TBL] [Abstract][Full Text] [Related]
14. Glutamate synthase. Properties of the glutamine-dependent activity.
Mäntsälä P; Zalkin H
J Biol Chem; 1976 Jun; 251(11):3294-9. PubMed ID: 6449
[TBL] [Abstract][Full Text] [Related]
15. Enzyme targets of antiglutamine agents in cancer chemotherapy.
Prajda N
Adv Enzyme Regul; 1985; 24():207-23. PubMed ID: 2424283
[TBL] [Abstract][Full Text] [Related]
16. Inactivation by acivicin of carbamoyl-phosphate synthetase II of human colon carcinoma.
Sebolt JS; Aoki T; Eble JN; Glover JL; Weber G
Biochem Pharmacol; 1985 Jan; 34(1):97-100. PubMed ID: 3966920
[TBL] [Abstract][Full Text] [Related]
17. Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase.
Allen LM; Corrigan MV; Meinking T
Chem Biol Interact; 1981 Jan; 33(2-3):361-5. PubMed ID: 6109574
[No Abstract] [Full Text] [Related]
18. Acivicin. An antitumor antibiotic.
Poster DS; Bruno S; Penta J; Neil GL; McGovren JP
Cancer Clin Trials; 1981; 4(3):327-30. PubMed ID: 7026076
[TBL] [Abstract][Full Text] [Related]
19. A cysteine-histidine-aspartate catalytic triad is involved in glutamine amide transfer function in purF-type glutamine amidotransferases.
Mei B; Zalkin H
J Biol Chem; 1989 Oct; 264(28):16613-9. PubMed ID: 2674138
[TBL] [Abstract][Full Text] [Related]
20. In vivo inactivation of formylglycinamidine ribonucleotide synthetase in rat hepatoma.
Elliott WL; Weber G
Biochem Pharmacol; 1985 Jan; 34(2):243-8. PubMed ID: 3966925
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
