These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 7049365)

  • 1. Ellipticine, 9-hydroxyellipticine, and 9-hydroxyellipiticinum: some biochemical properties of possible pharmacologic significance.
    Paoletti C; Auclair C; Lesca P; Tocanne JF; Malvy C; Pinto M
    Cancer Treat Rep; 1981; 65 Suppl 3():107-18. PubMed ID: 7049365
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The anticancer drug ellipticine forms covalent DNA adducts, mediated by human cytochromes P450, through metabolism to 13-hydroxyellipticine and ellipticine N2-oxide.
    Stiborová M; Sejbal J; Borek-Dohalská L; Aimová D; Poljaková J; Forsterová K; Rupertová M; Wiesner J; Hudecek J; Wiessler M; Frei E
    Cancer Res; 2004 Nov; 64(22):8374-80. PubMed ID: 15548707
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effects of ellipticine on cell survival and cell cycle progression in cultured mammalian cells.
    Traganos F; Staiano-Coico L; Darzynkiewicz Z; Melamed MR
    Cancer Res; 1980 Jul; 40(7):2390-9. PubMed ID: 6155993
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxic effects of the lysosomotropic agents DNA-ellipticine, DNA-daunorubicin, and DNA-ellipticine:daunorubicin on L1210 leukemia cells.
    Sorace RA; Sheid B
    Cancer Treat Rep; 1979 Jan; 63(1):43-51. PubMed ID: 421232
    [No Abstract]   [Full Text] [Related]  

  • 5. Cytochrome P450- and peroxidase-mediated oxidation of anticancer alkaloid ellipticine dictates its anti-tumor efficiency.
    Stiborová M; Rupertová M; Frei E
    Biochim Biophys Acta; 2011 Jan; 1814(1):175-85. PubMed ID: 20576524
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - similarity between human and rat systems.
    Stiborová M; Borek-Dohalská L; Aimová D; Kotrbová V; Kukacková K; Janouchová K; Rupertová M; Ryslavá H; Hudecek J; Frei E
    Gen Physiol Biophys; 2006 Sep; 25(3):245-61. PubMed ID: 17197724
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cytochromes P450 reconstituted with NADPH: P450 reductase mimic the activating and detoxicating metabolism of the anticancer drug ellipticine in microsomes.
    Kotrbová V; Aimová D; Brezinová A; Janouchová K; Poljaková J; Frei E; Stiborová M
    Neuro Endocrinol Lett; 2006 Dec; 27 Suppl 2():18-22. PubMed ID: 17159771
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidation of an antitumor drug ellipticine by peroxidases.
    Poljaková J; Forsterová K; Sulc M; Frei E; Stiborová M
    Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub; 2005 Dec; 149(2):449-53. PubMed ID: 16601808
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytochrome b5 increases cytochrome P450 3A4-mediated activation of anticancer drug ellipticine to 13-hydroxyellipticine whose covalent binding to DNA is elevated by sulfotransferases and N,O-acetyltransferases.
    Stiborová M; Indra R; Moserová M; Cerná V; Rupertová M; Martínek V; Eckschlager T; Kizek R; Frei E
    Chem Res Toxicol; 2012 May; 25(5):1075-85. PubMed ID: 22390216
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Sanguinarine and ellipticine cytotoxic alkaloids isolated from well-known antitumor plants. Intracellular targets of their action].
    Faddeeva MD; Beliaeva TN
    Tsitologiia; 1997; 39(2-3):181-208. PubMed ID: 9312909
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Influence of inducers of monooxygenases on cytotoxic efficiency of ellipticine on leukemia L1210 cells.
    Lesca P; Monsarrat B; Cros S; Paoletti C
    J Natl Cancer Inst; 1981 Oct; 67(4):871-6. PubMed ID: 6944554
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mammalian peroxidases activate anticancer drug ellipticine to intermediates forming deoxyguanosine adducts in DNA identical to those found in vivo and generated from 12-hydroxyellipticine and 13-hydroxyellipticine.
    Stiborová M; Poljaková J; Ryslavá H; Dracínský M; Eckschlager T; Frei E
    Int J Cancer; 2007 Jan; 120(2):243-51. PubMed ID: 17066455
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [9-Nitro- and 9-amino-ellipticines and derivatives: synthesis and pharmacologic properties].
    Gansser C; Viel C; Malvy C; Cros S
    Farmaco Sci; 1980 Nov; 35(11):887-95. PubMed ID: 7450021
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cytotoxicity of and DNA adduct formation by ellipticine in human U87MG glioblastoma cancer cells.
    Martinkova E; Dontenwill M; Frei E; Stiborova M
    Neuro Endocrinol Lett; 2009; 30 Suppl 1():60-6. PubMed ID: 20027146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytochrome b(5) shifts oxidation of the anticancer drug ellipticine by cytochromes P450 1A1 and 1A2 from its detoxication to activation, thereby modulating its pharmacological efficacy.
    Kotrbová V; Mrázová B; Moserová M; Martínek V; Hodek P; Hudeček J; Frei E; Stiborová M
    Biochem Pharmacol; 2011 Sep; 82(6):669-80. PubMed ID: 21683692
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stacking interactions between demethylated ellipticines and DNA base pairs--a quantum mechanical study.
    Sanyal NK; Roychoudhury M; Tiwari SN
    Indian J Biochem Biophys; 1990 Aug; 27(4):222-7. PubMed ID: 2286387
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The mechanism of cytotoxicity and DNA adduct formation by the anticancer drug ellipticine in human neuroblastoma cells.
    Poljaková J; Eckschlager T; Hrabeta J; Hrebacková J; Smutný S; Frei E; Martínek V; Kizek R; Stiborová M
    Biochem Pharmacol; 2009 May; 77(9):1466-79. PubMed ID: 19426684
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bioactivation of the antitumor drugs 9-hydroxyellipticine and derivatives by a peroxidase-hydrogen peroxide system.
    Auclair C; Paoletti C
    J Med Chem; 1981 Mar; 24(3):289-95. PubMed ID: 7265115
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rat microsomes activating the anticancer drug ellipticine to species covalently binding to deoxyguanosine in DNA are a suitable model mimicking ellipticine bioactivation in humans.
    Stiborová M; Stiborová-Rupertová M; Borek-Dohalská L; Wiessler M; Frei E
    Chem Res Toxicol; 2003 Jan; 16(1):38-47. PubMed ID: 12693029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Syntheses designed to produce 8-amino ellipticine. Synthesis and pharmacological properties of 8-nitro ellipticine].
    Gansser C; Lévque X; Plat M; Viel C
    Farmaco Sci; 1982 May; 37(5):283-97. PubMed ID: 7095141
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.