97 related articles for article (PubMed ID: 7082363)
1. Role of thymidine kinase in the inhibitory activity of 5-substituted-2'-deoxyuridines on the growth of human and murine tumor cell lines.
Balzarini J; De Clercq E; Torrence PF; Mertes MP; Park JS; Schmidt CL; Shugar D; Barr PJ; Jones AS; Verhelst G; Walker RT
Biochem Pharmacol; 1982 Mar; 31(6):1089-95. PubMed ID: 7082363
[TBL] [Abstract][Full Text] [Related]
2. 5-Substituted 2'-deoxyuridines: correlation between inhibition of tumor cell growth and inhibition of thymidine kinase and thymidylate synthetase.
Balzarini J; De Clercq E; Mertes MP; Shugar D; Torrence PF
Biochem Pharmacol; 1982 Nov; 31(22):3673-82. PubMed ID: 7181950
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and antitumor and antiviral properties of 5-alkyl-2'-deoxyuridines, 3',5'-cyclic monophosphates, and neutral cyclic triesters.
Bères J; Bentrude WG; Balzarini J; De Clercq E; Otvös L
J Med Chem; 1986 Apr; 29(4):494-9. PubMed ID: 3959027
[TBL] [Abstract][Full Text] [Related]
4. Role of deoxycytidine kinase in the inhibitory activity of 5-substituted 2'-deoxycytidines and cytosine arabinosides on tumor cell growth.
Balzarini J; De Clercq E
Mol Pharmacol; 1983 Jan; 23(1):175-81. PubMed ID: 6306422
[TBL] [Abstract][Full Text] [Related]
5. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
Béres J; Sági G; Bentrude WG; Balzarini J; De Clercq E; Otvös L
J Med Chem; 1986 Jul; 29(7):1243-9. PubMed ID: 3027328
[TBL] [Abstract][Full Text] [Related]
7. Inhibitory activity of diarylamidine derivatives on murine leukemia L1210 cell growth.
Balzarini J; de Clercq E; Dann O
Invest New Drugs; 1983; 1(2):103-15. PubMed ID: 6678860
[TBL] [Abstract][Full Text] [Related]
8. Thymidylate synthetase as target enzyme for the inhibitory activity of 5-substituted 2'-deoxyuridines on mouse leukemia L1210 cell growth.
De Clercq E; Balzarini J; Torrence PF; Mertes MP; Schmidt CL; Shugar D; Barr PJ; Jones AS; Verhelst G; Walker RT
Mol Pharmacol; 1981 Mar; 19(2):321-30. PubMed ID: 7231392
[No Abstract] [Full Text] [Related]
9. The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes.
Vande Voorde J; Liekens S; McGuigan C; Murziani PG; Slusarczyk M; Balzarini J
Biochem Pharmacol; 2011 Sep; 82(5):441-52. PubMed ID: 21658373
[TBL] [Abstract][Full Text] [Related]
10. Antitumor cell and antimetabolic effects of 5-ethyl-2'-deoxyuridine and 5'-substituted 5-ethyl-2'-deoxyuridine derivatives.
Balzarini J; De Clercq E; Kiefer G; Keppeler K; Buchele A
Invest New Drugs; 1984; 2(1):35-47. PubMed ID: 6469497
[TBL] [Abstract][Full Text] [Related]
11. Strategies for the measurement of the inhibitory effects of thymidine analogs on the activity of thymidylate synthase in intact murine leukemia L1210 cells.
Balzarini J; De Clercq E
Biochim Biophys Acta; 1984 Feb; 785(1-2):36-45. PubMed ID: 6696920
[TBL] [Abstract][Full Text] [Related]
12. Synthesis, antiviral and cytotoxic activity of 2'-deoxyuridines, 2'-fluoro-2'-deoxyuridines and 2'-arabinouridines containing 5-(1-hydroxy-2-halo-2-ethoxycarbonylethyl)-, 5-(1-hydroxy-2-iodo-2- carboxyethyl)- and 5-[1-hydroxy (or methoxy)-2-iodoethyl] substituents.
Kumar R; Wiebe LI; Knaus EE; Allen TM; Tempest ML
Drug Des Discov; 1992 Feb; 8(3):179-89. PubMed ID: 1326340
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, structure, and antitumor and antiviral activities of a series of 5-halouridine cyclic 3',5'-monophosphates.
Béres J; Bentrude WG; Kálmán A; Párkányi L; Balzarini J; De Clercq E
J Med Chem; 1986 Apr; 29(4):488-93. PubMed ID: 3007759
[TBL] [Abstract][Full Text] [Related]
14. Thymidylate synthetase and thymidine kinase activities and methotrexate cytotoxicity during growth of L1210 and Ehrlich ascites tumor.
Hullán L; Szikla K; Tusnády G; Holczinger L
Cancer Biochem Biophys; 1988 Nov; 10(2):131-9. PubMed ID: 3252959
[TBL] [Abstract][Full Text] [Related]
15. Sensitivity of leukemia cell lines to cytotoxic alkyl-lysophospholipids in relation to O-alkyl cleavage enzyme activities.
Unger C; Eibl H; Kim DJ; Fleer EA; Kötting J; Bartsch HH; Nagel GA; Pfizenmaier K
J Natl Cancer Inst; 1987 Feb; 78(2):219-22. PubMed ID: 3468284
[TBL] [Abstract][Full Text] [Related]
16. 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
Cristofoli WA; Wiebe LI; De Clercq E; Andrei G; Snoeck R; Balzarini J; Knaus EE
J Med Chem; 2007 Jun; 50(12):2851-7. PubMed ID: 17518459
[TBL] [Abstract][Full Text] [Related]
17. Synthesis of 5-[1-hydroxy(or methoxy)-2-bromo(or chloro)ethyl]-2'-deoxyuridines and related halohydrin analogues with antiviral and cytotoxic activity.
Kumar R; Wiebe LI; Hall TW; Knaus EE; Tovell DR; Tyrrell DL; Allen TM; Fathi-Afshar R
J Med Chem; 1989 May; 32(5):941-4. PubMed ID: 2709380
[TBL] [Abstract][Full Text] [Related]
18. Uracil derivatives. V. Syntheses and growth-inhibitory activity against L-1210 cells of 5-substituted 2'-deoxyuridines and orotidine derivatives.
Okada J; Nakano K; Miyake H
Chem Pharm Bull (Tokyo); 1985 Feb; 33(2):856-64. PubMed ID: 4017129
[No Abstract] [Full Text] [Related]
19. Synthesis and biological activity of various 3'-azido and 3'-amino analogues of 5-substituted pyrimidine deoxyribonucleosides.
Lin TS; Gao YS; Mancini WR
J Med Chem; 1983 Dec; 26(12):1691-6. PubMed ID: 6644738
[TBL] [Abstract][Full Text] [Related]
20. Antiviral and antitumor activities of 5-substituted 2'-deoxyuridines.
De Clercq E
Methods Find Exp Clin Pharmacol; 1980 Oct; 2(5):253-67. PubMed ID: 6765587
[No Abstract] [Full Text] [Related]
[Next] [New Search]