These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

93 related articles for article (PubMed ID: 708790)

  • 1. Binding of N5,N10-methylene tetrahydrofolate and the inhibition of thymidylate synthesis by a folate-binding protein.
    Rothenberg SP; Fischer CD; da Costa M
    Biochim Biophys Acta; 1978 Oct; 543(3):340-8. PubMed ID: 708790
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Flavin-dependent thymidylate synthase: N5 of flavin as a Methylene carrier.
    Karunaratne K; Luedtke N; Quinn DM; Kohen A
    Arch Biochem Biophys; 2017 Oct; 632():11-19. PubMed ID: 28821425
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.
    Bunni M; Doig MT; Donato H; Kesavan V; Priest DG
    Cancer Res; 1988 Jun; 48(12):3398-404. PubMed ID: 3370638
    [TBL] [Abstract][Full Text] [Related]  

  • 4. On the structure of the cofactor in the complex formed with thymidylate synthetase, 5,10-methylenetetrahy-drofolate and 5-fluoro-2'-deoxyuridylate.
    Santi DV; Penã VA; Lam SS
    Biochim Biophys Acta; 1976 Jun; 438(1):324-31. PubMed ID: 938684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional effects of amino acid substitutions at residue 33 of human thymidylate synthase.
    Reilly RT; Forsthoefel AM; Berger FG
    Arch Biochem Biophys; 1997 Jun; 342(2):338-43. PubMed ID: 9186496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role for cytosolic folate-binding proteins in the compartmentation of endogenous tetrahydrofolates and the 5-formyl tetrahydrofolate-mediated enhancement of 5-fluoro-2'-deoxyuridine antitumor activity in vitro.
    Matherly LH; Czajkowski CA; Muench SP; Psiakis JT
    Cancer Res; 1990 Jun; 50(11):3262-9. PubMed ID: 2139802
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nuclear morphology of yeast under thymidylate starvation.
    Moens PB; Barclay BJ; Little JG
    Chromosoma; 1981; 82(3):333-40. PubMed ID: 7014140
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Flavin-dependent thymidylate synthase ThyX activity: implications for the folate cycle in bacteria.
    Leduc D; Escartin F; Nijhout HF; Reed MC; Liebl U; Skouloubris S; Myllykallio H
    J Bacteriol; 2007 Dec; 189(23):8537-45. PubMed ID: 17890305
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 19F nuclear magnetic resonance investigation of the ternary complex formed between native thymidylate synthetase, 5-fluoro-2'-deoxyuridylate, and 5,10-methylenetetrahydrofolate.
    Byrd RA; Dawson WH; Ellis PD; Dunlap RB
    J Am Chem Soc; 1977 Aug; 99(18):6139-41. PubMed ID: 893883
    [No Abstract]   [Full Text] [Related]  

  • 10. Enhancement by thymidine of 5-fluorouracil's inhibition of thymidylate synthetase in human tumors.
    Wolberg WH
    Cancer Treat Rep; 1979; 63(11-12):1817-20. PubMed ID: 526916
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Secondary alpha-hydrogen isotope effects on the interaction of 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate with thymidylate synthetase.
    Bruice TW; Santi DV
    Biochemistry; 1982 Dec; 21(26):6703-9. PubMed ID: 7159556
    [No Abstract]   [Full Text] [Related]  

  • 12. Biochemistry. DNA building block reinvented.
    Murzin AG
    Science; 2002 Jul; 297(5578):61-2. PubMed ID: 12029066
    [No Abstract]   [Full Text] [Related]  

  • 13. Stereochemical mechanism of action for thymidylate synthase based on the X-ray structure of the covalent inhibitory ternary complex with 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate.
    Matthews DA; Villafranca JE; Janson CA; Smith WW; Welsh K; Freer S
    J Mol Biol; 1990 Aug; 214(4):937-48. PubMed ID: 2201779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. trans-5-(3,3,3-Trifluoro-1-propenyl-)-2'-deoxyuridylate: a mechanism-based inhibitor of thymidylate synthetase.
    Wataya Y; Matsuda A; Santi DV; Bergstrom DE; Ruth JL
    J Med Chem; 1979 Apr; 22(4):339-40. PubMed ID: 430474
    [No Abstract]   [Full Text] [Related]  

  • 15. Human thymidylate synthetase--III. Effects of methotrexate and folate analogs.
    Szeto DW; Cheng YC; Rosowsky A; Yu CS; Modest EJ; Piper JR; Temple C; Elliott RD; Rose JD; Montgomery JA
    Biochem Pharmacol; 1979 Sep; 28(17):2633-7. PubMed ID: 518674
    [No Abstract]   [Full Text] [Related]  

  • 16. Folate analogues altered in the C9-N10 bridge region: N10-Toxylisohomofolic acid and N10-Toxylisohomoaminopterin.
    Nair MG; O'Neal PC; Baugh CM; Kisliuk RL; Gaumont Y; Rodman M
    J Med Chem; 1978 Jul; 21(7):673-7. PubMed ID: 97383
    [No Abstract]   [Full Text] [Related]  

  • 17. Are the redox properties of tetrahydrofolate cofactors utilized in folate-dependent reactions?
    Matthews RG
    Fed Proc; 1982 Jul; 41(9):2600-4. PubMed ID: 7044835
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells.
    Scanlon KJ; Newman EM; Lu Y; Priest DG
    Proc Natl Acad Sci U S A; 1986 Dec; 83(23):8923-5. PubMed ID: 3466165
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Microscale synthesis of isotopically labeled R-[6-xH]N5,N10-methylene-5,6,7,8-tetrahydrofolate as a cofactor for thymidylate synthase.
    Agrawal N; Mihai C; Kohen A
    Anal Biochem; 2004 May; 328(1):44-50. PubMed ID: 15081906
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical and cellular pharmacology of 1843U89, a novel benzoquinazoline inhibitor of thymidylate synthase.
    Duch DS; Banks S; Dev IK; Dickerson SH; Ferone R; Heath LS; Humphreys J; Knick V; Pendergast W; Singer S
    Cancer Res; 1993 Feb; 53(4):810-8. PubMed ID: 8428362
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.