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2. Antifolate-resistant Chinese hamster cells. Evidence for dihydrofolate reductase gene amplification among independently derived sublines overproducing different dihydrofolate reductases. Melera PW; Lewis JA; Biedler JL; Hession C J Biol Chem; 1980 Jul; 255(14):7024-8. PubMed ID: 7391066 [TBL] [Abstract][Full Text] [Related]
3. Antifolate-resistant chinese hamster cells. Evidence from independently derived sublines for the overproduction of two dihydrofolate reductases encoded by different mRNAs. Melera PW; Wolgemuth D; Biedler JL; Hession C J Biol Chem; 1980 Jan; 255(2):319-22. PubMed ID: 7356612 [TBL] [Abstract][Full Text] [Related]
4. Antifolate-resistant Chinese hamster cells. Molecular basis for the biochemical and structural heterogeneity among dihydrofolate reductases produced by drug-sensitive and drug-resistant cell lines. Melera PW; Davide JP; Oen H J Biol Chem; 1988 Feb; 263(4):1978-90. PubMed ID: 3339001 [TBL] [Abstract][Full Text] [Related]
5. Selective amplification of polymorphic dihydrofolate reductase gene loci in Chinese hamster lung cells. Lewis JA; Davide JP; Melera PW Proc Natl Acad Sci U S A; 1982 Nov; 79(22):6961-5. PubMed ID: 6184719 [TBL] [Abstract][Full Text] [Related]
6. Molecular cloning of Chinese hamster dihydrofolate reductase-specific cDNA and the identification of multiple dihydrofolate reductase mRNAs in antifolate-resistant Chinese hamster lung fibroblasts. Lewis JA; Kurtz DT; Melera PW Nucleic Acids Res; 1981 Mar; 9(6):1311-22. PubMed ID: 6262725 [TBL] [Abstract][Full Text] [Related]
7. Allelic variation in the dihydrofolate reductase gene at amino acid position 95 contributes to antifolate resistance in Chinese hamster cells. Yu M; Melera PW Cancer Res; 1993 Dec; 53(24):6031-5. PubMed ID: 8261418 [TBL] [Abstract][Full Text] [Related]
8. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate. Assaraf YG; Molina A; Schimke RT J Biol Chem; 1989 Nov; 264(31):18326-34. PubMed ID: 2572592 [TBL] [Abstract][Full Text] [Related]
9. Gene amplification accompanies low level increases in the activity of dihydrofolate reductase in antifolate-resistant Chinese hamster lung cells containing abnormally banding chromosomes. Lewis JA; Biedler JL; Melera PW J Cell Biol; 1982 Aug; 94(2):418-24. PubMed ID: 7107708 [TBL] [Abstract][Full Text] [Related]
10. Amplification of a cloned Chinese hamster dihydrofolate reductase gene after transfer into a dihydrofolate reductase-deficient cell line. Milbrandt JD; Azizkhan JC; Hamlin JL Mol Cell Biol; 1983 Jul; 3(7):1274-82. PubMed ID: 6310371 [TBL] [Abstract][Full Text] [Related]
11. Similar 150-kilobase DNA sequences are amplified in independently derived methotrexate-resistant Chinese hamster cells. Montoya-Zavala M; Hamlin JL Mol Cell Biol; 1985 Apr; 5(4):619-27. PubMed ID: 2985962 [TBL] [Abstract][Full Text] [Related]
13. Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells. Flintoff WF; Weber MK; Nagainis CR; Essani AK; Robertson D; Salser W Mol Cell Biol; 1982 Mar; 2(3):275-85. PubMed ID: 6287233 [TBL] [Abstract][Full Text] [Related]
14. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate. Fanin R; Banerjee D; Volkenandt M; Waltham M; Li WW; Dicker AP; Schweitzer BI; Bertino JR Mol Pharmacol; 1993 Jul; 44(1):13-21. PubMed ID: 8341268 [TBL] [Abstract][Full Text] [Related]
15. [Localization of dihydrofolate reductase amplified genes in Chinese hamster cells resistant to methotrexate]. Mukhamedkhanova FS; Kuznetsova NN; Nuridzhaniants SS; Abdurkarimov AA Genetika; 1987 Sep; 23(9):1588-94. PubMed ID: 3692154 [TBL] [Abstract][Full Text] [Related]
16. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells. Sharma RC; Assaraf YG; Schimke RT Cancer Res; 1991 Jun; 51(11):2949-59. PubMed ID: 1674447 [TBL] [Abstract][Full Text] [Related]
17. Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line. Kaufman RJ; Schimke RT Mol Cell Biol; 1981 Dec; 1(12):1069-76. PubMed ID: 7346712 [TBL] [Abstract][Full Text] [Related]
18. Gene amplification-associated cytogenetic aberrations and protein changes in vincristine-resistant Chinese hamster, mouse, and human cells. Meyers MB; Spengler BA; Chang TD; Melera PW; Biedler JL J Cell Biol; 1985 Feb; 100(2):588-97. PubMed ID: 3968181 [TBL] [Abstract][Full Text] [Related]
19. A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture. Biedler JL; Spengler BA J Natl Cancer Inst; 1976 Sep; 57(3):683-95. PubMed ID: 62055 [TBL] [Abstract][Full Text] [Related]
20. The dihydrofolate reductase amplicons in different methotrexate-resistant Chinese hamster cell lines share at least a 273-kilobase core sequence, but the amplicons in some cell lines are much larger and are remarkably uniform in structure. Looney JE; Ma C; Leu TH; Flintoff WF; Troutman WB; Hamlin JL Mol Cell Biol; 1988 Dec; 8(12):5268-79. PubMed ID: 3244355 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]