BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 7142200)

  • 1. A new fluorescent dihydrofolate reductase probe for studies of methotrexate resistance.
    Rosowsky A; Wright JE; Shapiro H; Beardsley P; Lazarus H
    J Biol Chem; 1982 Dec; 257(23):14162-7. PubMed ID: 7142200
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A fluorescent analogue of methotrexate as a probe for folate antagonist molecular receptors.
    Susten SS; Kempton RJ; Black AM; Freisheim JH
    Biochem Pharmacol; 1984 Jun; 33(12):1957-62. PubMed ID: 6732854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Methotrexate analogues. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N epsilon-(haloacetyl)-L-lysine and N delta-(haloacetyl)-L-ornithine analogues and an acivicin analogue of methotrexate.
    Rosowsky A; Solan VC; Forsch RA; Delcamp TJ; Baccanari DP; Freisheim JH
    J Med Chem; 1987 Aug; 30(8):1463-9. PubMed ID: 3112397
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction of 1,N6-ethenoadenine derivatives of triphosphopyridine and reduced triphosphopyridine nucleotides with dihydrofolate reductase from amethopterin-resistant L1210 cells.
    Neef VG; Huennekens FM
    Biochemistry; 1976 Sep; 15(18):4042-7. PubMed ID: 9129
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The use of a fluorescent methotrexate probe to monitor the effects of three vinca alkaloids on a mixed population of parental L1210 and gene-amplified methotrexate-resistant cells by flow cytometry.
    Poppitt DG; McGown AT; Fox BW
    Cancer Chemother Pharmacol; 1984; 13(1):54-7. PubMed ID: 6733843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Immunologic heterogeneity of dihydrofolate reductase from methotrexate sensitive and resistant L1210 leukemia cells.
    Iqbal MP; Rothenberg SP; Larosa C
    Proc Soc Exp Biol Med; 1985 Oct; 180(1):98-102. PubMed ID: 2412235
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antifolate polyglutamylation and competitive drug displacement at dihydrofolate reductase as important elements in leucovorin rescue in L1210 cells.
    Matherly LH; Barlowe CK; Goldman ID
    Cancer Res; 1986 Feb; 46(2):588-93. PubMed ID: 2416428
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Elevated dihydrofolate reductase and impaired methotrexate transport as elements in methotrexate resistance in childhood acute lymphoblastic leukemia.
    Matherly LH; Taub JW; Ravindranath Y; Proefke SA; Wong SC; Gimotty P; Buck S; Wright JE; Rosowsky A
    Blood; 1995 Jan; 85(2):500-9. PubMed ID: 7812005
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multiple forms of L1210 dihydrofolate reductase differing in affinity for methotrexate.
    Duffy TH; Beckman SB; Huennekens FM
    Biochem Biophys Res Commun; 1984 Feb; 119(1):352-8. PubMed ID: 6704125
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Polymorphism of dihydrofolate reductase from a methotrexate-resistant subline of L1210 cells.
    Duffy TH; Beckman SB; Sato JK; Nagae H; Vitols KS; Huennekens FM
    Adv Enzyme Regul; 1985; 23():3-12. PubMed ID: 4072799
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrate and inhibitor complexes of dihydrofolate reductase from amethopterin-resistant L1210 cells.
    Neef VG; Huennekens FM
    Arch Biochem Biophys; 1975 Dec; 171(2):435-43. PubMed ID: 959
    [No Abstract]   [Full Text] [Related]  

  • 12. A fluorescent derivative of methotrexate as an intracellular marker for dihydrofolate reductase in L1210 cells.
    Henderson GB; Russell A; Whiteley JM
    Arch Biochem Biophys; 1980 Jun; 202(1):29-34. PubMed ID: 6772112
    [No Abstract]   [Full Text] [Related]  

  • 13. Synthesis of methotrexate polyglutamates in L1210 murine leukemia cells.
    Whitehead VM
    Cancer Res; 1977 Feb; 37(2):408-12. PubMed ID: 832265
    [TBL] [Abstract][Full Text] [Related]  

  • 14. L1210 dihydrofolate reductase: activation and enhancement of methotrexate sensitivity.
    Duffy TH; Sato JK; Vitols KS; Huennekens FM
    Adv Enzyme Regul; 1985; 24():13-25. PubMed ID: 3835818
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Limited effectiveness of in vitro high-dose methotrexate and leucovorin to overcome resistance in L1210 leukemia cells with elevations of dihydrofolate reductase.
    Bruckner H; Rubinoff M; Waxman S
    Eur J Cancer (1965); 1980 Aug; 16(8):1057-63. PubMed ID: 6969180
    [No Abstract]   [Full Text] [Related]  

  • 16. Regiospecific gamma-conjugation of methotrexate to poly(L-lysine). Chemical and biological studies.
    Rosowsky A; Forsch RA; Galivan J; Susten SS; Freisheim JH
    Mol Pharmacol; 1985 Jan; 27(1):141-7. PubMed ID: 3965926
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Methotrexate analogues. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogues containing a basic amino acid side chain.
    Rosowsky A; Freisheim JH; Moran RG; Solan VC; Bader H; Wright JE; Radike-Smith M
    J Med Chem; 1986 May; 29(5):655-60. PubMed ID: 2871191
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methotrexate analogues. 23. Synthesis, dihydrofolate reductase affinity, cytotoxicity, and in vivo antitumor activity of some putative degradation products of methotrexate-poly(L-lysine) conjugates.
    Rosowsky A; Forsch RA; Freisheim JH; Galivan J; Wick M
    J Med Chem; 1984 Jul; 27(7):888-93. PubMed ID: 6737432
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Fluorescent analogues of methotrexate: characterization and interaction with dihydrofolate reductase.
    Kumar AA; Kempton RJ; Anstead GM; Freisheim JH
    Biochemistry; 1983 Jan; 22(2):390-5. PubMed ID: 6402009
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Photoaffinity analogues of methotrexate as folate antagonist binding probes. 1. Photoaffinity labeling of murine L1210 dihydrofolate reductase and amino acid sequence of the binding region.
    Price EM; Smith PL; Klein TE; Freisheim JH
    Biochemistry; 1987 Jul; 26(15):4751-6. PubMed ID: 3663623
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.