BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

104 related articles for article (PubMed ID: 7259755)

  • 1. Molecular pharmacology of the haloethyl nitrosoureas: formation of 6-hydroxyethylguanine in DNA treated with BCNU (N,N1-bis[2-chloroethyl]-N-nitrosourea).
    Tong WP; Kirk MC; Ludlum DB
    Biochem Biophys Res Commun; 1981 May; 100(1):351-7. PubMed ID: 7259755
    [No Abstract]   [Full Text] [Related]  

  • 2. Formation of the cross-linked base, diguanylethane, in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.
    Tong WP; Ludlum DB
    Cancer Res; 1981 Feb; 41(2):380-2. PubMed ID: 7448781
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanism of action of the nitrosoureas--V. Formation of O6-(2-fluoroethyl)guanine and its probable role in the crosslinking of deoxyribonucleic acid.
    Tong WP; Kirk MC; Ludlum DB
    Biochem Pharmacol; 1983 Jul; 32(13):2011-5. PubMed ID: 6870930
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Formation of the cross-link 1-[N3-deoxycytidyl),2-[N1-deoxyguanosinyl]ethane in DNA treated with N,N'-bis(2-chloroethyl)-N-nitrosourea.
    Tong WP; Kirk MC; Ludlum DB
    Cancer Res; 1982 Aug; 42(8):3102-5. PubMed ID: 7093954
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of action of the nitrosoureas: formation of 1,2-(diguanosin-7-yl) ethane from the reaction of BCNU (1,3-bis-[2-chloroethyl]-1-nitrosourea) with guanosine.
    Gombar CT; Tong WP; Ludlum DB
    Biochem Biophys Res Commun; 1979 Oct; 90(3):878-82. PubMed ID: 508350
    [No Abstract]   [Full Text] [Related]  

  • 6. Mechanism of action of (2-haloethyl)nitrosoureas on DNA. Isolation and reactions of postulated 2-(alkylimino)-3-nitrosooxazolidine intermediates in the decomposition of 1,3-bis(2-chloroethyl)-, 1-(2-chloroethyl)-3-cyclohexyl-, and 1-(2-chloroethyl)-3-(4'-trans-methylcyclohexyl)-1-nitrosourea.
    Lown JW; Chauhan SM
    J Med Chem; 1981 Mar; 24(3):270-9. PubMed ID: 7265113
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureas.
    Kohn KW
    Cancer Res; 1977 May; 37(5):1450-4. PubMed ID: 851960
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modifications of DNA by different haloethylnitrosoureas.
    Tong WP; Kohn KW; Ludlum DB
    Cancer Res; 1982 Nov; 42(11):4460-4. PubMed ID: 7127289
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemistry of nitrosoureas. Decomposition of Deuterated 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Brundrett RB; Cowens JW; Colvin M
    J Med Chem; 1976 Jul; 19(7):958-61. PubMed ID: 940114
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of action of the nitrosoureas -- III. Reactions of bis-chloroethyl nitrosourea and bis-fluoroethyl nitrosourea with adenosine.
    Tong WP; Ludlum DB
    Biochem Pharmacol; 1979 Apr; 28(7):1175-9. PubMed ID: 444275
    [No Abstract]   [Full Text] [Related]  

  • 11. Microsomal metabolism of nitrosoureas.
    Hill DL; Kirk MC; Struck RF
    Cancer Res; 1975 Feb; 35(2):296-301. PubMed ID: 234031
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Levels and distribution of BCNU in GBM tumors following intratumoral injection of DTI-015 (BCNU-ethanol).
    Bodell WJ; Bodell AP; Giannini DD
    Neuro Oncol; 2007 Jan; 9(1):12-9. PubMed ID: 17018699
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and characterization of O6-(2-chloroethyl)guanine: a putative intermediate in the cytotoxic reaction of chloroethylnitrosoureas with DNA.
    Parker S; Kirk MC; Ludlum DB
    Biochem Biophys Res Commun; 1987 Nov; 148(3):1124-8. PubMed ID: 3689390
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice.
    Bibby MC; Thompson MJ; Rafferty JA; Margison GP; McElhinney RS
    Br J Cancer; 1999 Mar; 79(9-10):1332-9. PubMed ID: 10188873
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decomposition of N-(2-chloroethyl)-N-nitrosoureas in aqueous media.
    Montgomery JA; James R; McCaleb GS; Kirk MC; Johnston TP
    J Med Chem; 1975 Jun; 18(6):568-71. PubMed ID: 1151969
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nature and biological significance of DNA modification by the haloethylnitrosoureas.
    Ludlum DB
    IARC Sci Publ; 1986; (78):71-81. PubMed ID: 3583399
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas.
    Stahl W; Krauth-Siegel RL; Schirmer RH; Eisenbrand G
    IARC Sci Publ; 1987; (84):191-3. PubMed ID: 2960614
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanism of action of the nitrosoureas--IV. Reactions of bis-chloroethyl nitrosourea and chloroethyl cyclohexyl nitrosourea with deoxyribonucleic acid.
    Gombar CT; Tong WP; Ludlum DB
    Biochem Pharmacol; 1980 Oct; 29(19):2639-43. PubMed ID: 7191706
    [No Abstract]   [Full Text] [Related]  

  • 19. Synthesis of N7-hydroxyethylguanine and O6-hydroxyethylguanine. Markers for the reaction of ethylene oxide (EO) with DNA.
    Ashby J; Paton D; Styles JA; Greatbanks D; Wright B
    Mutat Res; 1982 Mar; 103(3-6):257-61. PubMed ID: 7087988
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 6.