These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 7273001)

  • 21. N-(Phosphonacetyl)-L-aspartate inhibition of the enzyme complex of pyrimidine biosynthesis.
    Moore EC
    Biochem Pharmacol; 1982 Oct; 31(20):3313-6. PubMed ID: 7150357
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mechanism of resistance of variants of the Lewis lung carcinoma to N-(phosphonacetyl)-L-aspartic acid.
    Kensler TW; Mutter G; Hankerson JG; Reck LJ; Harley C; Han N; Ardalan B; Cysyk RL; Johnson RK; Jayaram HN; Cooney DA
    Cancer Res; 1981 Mar; 41(3):894-904. PubMed ID: 7459875
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.
    Johnson RK; Swyryd EA; Stark GR
    Cancer Res; 1978 Feb; 38(2):371-8. PubMed ID: 620408
    [No Abstract]   [Full Text] [Related]  

  • 24. An enzymatic technique for measuring N-phosphonacetyl-L-aspartic acid in tissues.
    Cooney DA; Karlowicz MG; Cubillan J; Roettger M; Jayaram HN
    Cancer Treat Rep; 1978 Oct; 62(10):1503-7. PubMed ID: 361225
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Collateral sensitivity to N-(phosphonacetyl)-L-aspartic acid in a line of P388 leukemia cells selected for resistance to L-(alpha S, 5S)-alpha-amino-3- chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Ardalan B; Jayaram HN; Johnson RK
    Cancer Res; 1983 Apr; 43(4):1598-601. PubMed ID: 6831405
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Growth inhibitory effect of N-(phosphonacetyl)-L-aspartic acid on human myeloid leukemia-derived cell lines and modulation by dipyridamole.
    Taguchi H; Kubonishi I; Miyoshi I
    Anticancer Res; 1989; 9(4):845-8. PubMed ID: 2817812
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effects of acivicin and PALA, singly and in combination, on de novo pyrimidine biosynthesis.
    Kensler TW; Jayaram HN; Cooney DA
    Adv Enzyme Regul; 1982; 20():57-73. PubMed ID: 7113804
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Binding of radiolabeled N-(phosphonacetyl)-L-aspartate to aspartate transcarbamylase from Ehrlich ascites tumor cells.
    White JC; Hines LH
    Biochem Pharmacol; 1984 Nov; 33(22):3645-8. PubMed ID: 6508821
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.
    Moyer JD; Smith PA; Levy EJ; Handschumacher RE
    Cancer Res; 1982 Nov; 42(11):4525-31. PubMed ID: 7127293
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.
    Smith KA; Chernova OB; Groves RP; Stark MB; Martínez JL; Davidson JN; Trent JM; Patterson TE; Agarwal A; Duncan P; Agarwal ML; Stark GR
    Proc Natl Acad Sci U S A; 1997 Mar; 94(5):1816-21. PubMed ID: 9050862
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.
    Poupon MF; Smith KA; Chernova OB; Gilbert C; Stark GR
    Mol Biol Cell; 1996 Mar; 7(3):345-54. PubMed ID: 8868464
    [TBL] [Abstract][Full Text] [Related]  

  • 32. MYC abrogates p53-mediated cell cycle arrest in N-(phosphonacetyl)-L-aspartate-treated cells, permitting CAD gene amplification.
    Chernova OB; Chernov MV; Ishizaka Y; Agarwal ML; Stark GR
    Mol Cell Biol; 1998 Jan; 18(1):536-45. PubMed ID: 9418900
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Efficient synthesis of fluorothiosparfosic acid analogues with potential antitumoral activity.
    Pfund E; Lequeux T; Masson S; Vazeux M; Cordi A; Pierre A; Serre V; Hervé G
    Bioorg Med Chem; 2005 Aug; 13(16):4921-8. PubMed ID: 15975800
    [TBL] [Abstract][Full Text] [Related]  

  • 34. A facile enzymatic technique for the estimation of nanomolar concentrations of N-phosphonacetyl-L-aspartic acid in plasma.
    Kensler TW; Jayaram HN; Cooney DA
    J Biochem Biophys Methods; 1980; 2(1):29-35. PubMed ID: 6999068
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Embryotoxicity in mice of phosphonacetyl-L-aspartic acid (PALA), a new antitumor agent. I. Embryolethal, teratogenic, and cytogenetic effects.
    Sieber SM; Botkin CC; Soong P; Lee EC; Whang-Peng J
    Teratology; 1980 Dec; 22(3):311-9. PubMed ID: 7233336
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Pharmacological and biochemical interactions of N-(phosphonacetyl)-L-aspartate and 5-fluorouracil in beagles.
    Miller AA; Moore EC; Hurlbert RB; Benvenuto JA; Loo TL
    Cancer Res; 1983 Jun; 43(6):2565-70. PubMed ID: 6189583
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential effect of N-(phosphonacetyl)-L-aspartate on 1-beta-D-arabinofuranosylcytosine metabolism and cytotoxicity in human leukemia and normal bone marrow progenitors.
    Grant S; Rauscher F; Cadman E
    Cancer Res; 1982 Oct; 42(10):4007-13. PubMed ID: 6955007
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Antitumor activity of the weekly intravenous push schedule of 5-fluoro-2'-deoxyuridine +/- N-phosphonacetyl-L-aspartate in mice bearing advanced colon carcinoma 26.
    van Laar JA; Durrani FA; Rustum YM
    Cancer Res; 1993 Apr; 53(7):1560-4. PubMed ID: 8453623
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphonacetyl)-L-aspartate-resistant hamster cells.
    Wahl GM; Padgett RA; Stark GR
    J Biol Chem; 1979 Sep; 254(17):8679-89. PubMed ID: 381311
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Co-amplification of rRNA genes with CAD genes in N-(phosphonacetyl)-L-aspartate-resistant Syrian hamster cells.
    Wahl GM; Vitto L; Rubnitz J
    Mol Cell Biol; 1983 Nov; 3(11):2066-75. PubMed ID: 6318080
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.