175 related articles for article (PubMed ID: 7346154)
1. On the rational development of a new drug: the example of the fluorinated pyrimidines.
Heidelberger C
Cancer Treat Rep; 1981; 65 Suppl 3():3-9. PubMed ID: 7346154
[TBL] [Abstract][Full Text] [Related]
2. Biochemical determinants of 5-fluorouracil response in vivo. The role of deoxyuridylate pool expansion.
Myers CE; Young RC; Chabner BA
J Clin Invest; 1975 Nov; 56(5):1231-8. PubMed ID: 1184747
[TBL] [Abstract][Full Text] [Related]
3. Resistance of a human ovarian cancer line to 5-fluorouracil associated with decreased levels of 5-fluorouracil in DNA.
Chu E; Lai GM; Zinn S; Allegra CJ
Mol Pharmacol; 1990 Sep; 38(3):410-7. PubMed ID: 2402230
[TBL] [Abstract][Full Text] [Related]
4. Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil.
Berger SH; Hakala MT
Mol Pharmacol; 1984 Mar; 25(2):303-9. PubMed ID: 6608049
[TBL] [Abstract][Full Text] [Related]
5. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
Ren Q; Van Groeningen CJ; Hardcastle A; Aherne GW; Geoffroy F; Allegra CJ; Johnston PG; Grem JL
Oncol Res; 1997; 9(2):77-88. PubMed ID: 9167189
[TBL] [Abstract][Full Text] [Related]
6. Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Rustum YM; Danhauser L; Luccioni C; Au JL
Cancer Treat Rep; 1981; 65 Suppl 3():73-82. PubMed ID: 7049369
[TBL] [Abstract][Full Text] [Related]
7. Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.
Houghton JA; Maroda SJ; Phillips JO; Houghton PJ
Cancer Res; 1981 Jan; 41(1):144-9. PubMed ID: 7448754
[TBL] [Abstract][Full Text] [Related]
8. Acyclic analogues of 5-fluoro-dUMP and 5-fluoro-2'-deoxyuridine: synthesis and inhibition of thymidylate synthase and tumour cell growth.
Felczak K; Gołos B; Dzik JM; Rode W; Bretner M; Shugar D; Kulikowski T
Acta Biochim Pol; 1998; 45(1):75-82. PubMed ID: 9701498
[TBL] [Abstract][Full Text] [Related]
9. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
10. The target cell determinants of the antitumor actions of 5-FU: does FU incorporation into RNA play a role?
Mandel HG
Cancer Treat Rep; 1981; 65 Suppl 3():63-71. PubMed ID: 6179616
[TBL] [Abstract][Full Text] [Related]
11. Sequential methotrexate and 5-fluorouracil: mechanisms of synergy.
Bertino JR; Mini E; Fernandes DJ
Semin Oncol; 1983 Jun; 10(2 Suppl 2):2-5. PubMed ID: 6867754
[TBL] [Abstract][Full Text] [Related]
12. Assay of intracellular free and macromolecular-bound metabolites of 5-fluorodeoxyuridine and 5-fluorouracil.
Washtien WL; Santi DV
Cancer Res; 1979 Sep; 39(9):3397-404. PubMed ID: 157805
[TBL] [Abstract][Full Text] [Related]
13. [Clinical pharmacology of anticancer agents (Part 4). Antimetabolites (1)].
Nakamura T; Uchida M; Ueda T
Gan To Kagaku Ryoho; 1992 Feb; 19(2):265-76. PubMed ID: 1736842
[TBL] [Abstract][Full Text] [Related]
14. Sequential methotrexate/5-FU: FdUMP formation and TS inhibition in a transplantable rodent colon adenocarcinoma.
Berne MH; Gustavsson BG; Almersjö O; Spears PC; Frösing R
Cancer Chemother Pharmacol; 1986; 16(3):237-42. PubMed ID: 3698165
[TBL] [Abstract][Full Text] [Related]
15. Functional effects of amino acid substitutions at residue 33 of human thymidylate synthase.
Reilly RT; Forsthoefel AM; Berger FG
Arch Biochem Biophys; 1997 Jun; 342(2):338-43. PubMed ID: 9186496
[TBL] [Abstract][Full Text] [Related]
16. Enhancement by thymidine of 5-fluorouracil's inhibition of thymidylate synthetase in human tumors.
Wolberg WH
Cancer Treat Rep; 1979; 63(11-12):1817-20. PubMed ID: 526916
[TBL] [Abstract][Full Text] [Related]
17. Thymidylate synthetase activity and fluorouracil sensitivity of human colonic cancer and normal mucosal tissue preparations.
Wolberg WH; Morin J
Cancer; 1981 Mar; 47(6):1313-7. PubMed ID: 7226054
[TBL] [Abstract][Full Text] [Related]
18. Biochemical determinants of tumor sensitivity to 5-fluorouracil: ultrasensitive methods for the determination of 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthetase.
Moran RG; Spears CP; Heidelberger C
Proc Natl Acad Sci U S A; 1979 Mar; 76(3):1456-60. PubMed ID: 108681
[TBL] [Abstract][Full Text] [Related]
19. Relationship between 5-fluoro-2'-deoxyuridylate, 2'-deoxyuridylate, and thymidylate synthase activity subsequent to 5-fluorouracil administration, in xenografts of human colon adenocarcinomas.
Houghton JA; Weiss KD; Williams LG; Torrance PM; Houghton PJ
Biochem Pharmacol; 1986 Apr; 35(8):1351-8. PubMed ID: 3008760
[TBL] [Abstract][Full Text] [Related]
20. Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS.
Carli D; Honorat M; Cohen S; Megherbi M; Vignal B; Dumontet C; Payen L; Guitton J
J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Oct; 877(27):2937-44. PubMed ID: 19620028
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]