BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 7473547)

  • 1. Piperazinylalkyl heterocycles as potential antipsychotic agents.
    Scott MK; Baxter EW; Bennett DJ; Boyd RE; Blum PS; Codd EE; Kukla MJ; Malloy E; Maryanoff BE; Maryanoff CA
    J Med Chem; 1995 Oct; 38(21):4198-210. PubMed ID: 7473547
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-aryl-N'-benzylpiperazines as potential antipsychotic agents.
    Reitz AB; Baxter EW; Bennett DJ; Codd EE; Jordan AD; Malloy EA; Maryanoff BE; McDonnell ME; Ortegon ME; Renzi MJ
    J Med Chem; 1995 Oct; 38(21):4211-22. PubMed ID: 7473548
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Orally active benzamide antipsychotic agents with affinity for dopamine D2, serotonin 5-HT1A, and adrenergic alpha1 receptors.
    Reitz AB; Baxter EW; Codd EE; Davis CB; Jordan AD; Maryanoff BE; Maryanoff CA; McDonnell ME; Powell ET; Renzi MJ; Schott MR; Scott MK; Shank RP; Vaught JL
    J Med Chem; 1998 Jun; 41(12):1997-2009. PubMed ID: 9622541
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyrrole mannich bases as potential antipsychotic agents.
    Scott MK; Martin GE; DiStefano DL; Fedde CL; Kukla MJ; Barrett DL; Baldy WJ; Elgin RJ; Kesslick JM; Mathiasen JR
    J Med Chem; 1992 Feb; 35(3):552-8. PubMed ID: 1346653
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
    López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
    J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Block of conditioned avoidance responding in the rat by substituted phenylpiperazines.
    Martin GE; Elgin RJ; Kesslick JM; Baldy WJ; Mathiasen JR; Shank RP; Scott MK
    Eur J Pharmacol; 1988 Nov; 156(2):223-9. PubMed ID: 3240768
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyrrolo[1,3]benzothiazepine-based serotonin and dopamine receptor antagonists. Molecular modeling, further structure-activity relationship studies, and identification of novel atypical antipsychotic agents.
    Campiani G; Butini S; Fattorusso C; Catalanotti B; Gemma S; Nacci V; Morelli E; Cagnotto A; Mereghetti I; Mennini T; Carli M; Minetti P; Di Cesare MA; Mastroianni D; Scafetta N; Galletti B; Stasi MA; Castorina M; Pacifici L; Vertechy M; Di Serio S; Ghirardi O; Tinti O; Carminati P
    J Med Chem; 2004 Jan; 47(1):143-57. PubMed ID: 14695828
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polycyclic aryl- and heteroarylpiperazinyl imides as 5-HT1A receptor ligands and potential anxiolytic agents: synthesis and structure-activity relationship studies.
    Abou-Gharbia M; Patel UR; Webb MB; Moyer JA; Andree TH; Muth EA
    J Med Chem; 1988 Jul; 31(7):1382-92. PubMed ID: 2898533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
    Martin GE; Elgin RJ; Mathiasen JR; Davis CB; Kesslick JM; Baldy WJ; Shank RP; DiStefano DL; Fedde CL; Scott MK
    J Med Chem; 1989 May; 32(5):1052-6. PubMed ID: 2565400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhanced D1 affinity in a series of piperazine ring substituted 1-piperazino-3-arylindans with potential atypical antipsychotic activity.
    Bøgesø KP; Arnt J; Frederiksen K; Hansen HO; Hyttel J; Pedersen H
    J Med Chem; 1995 Oct; 38(22):4380-92. PubMed ID: 7473566
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
    Bojarski AJ; Paluchowska MH; Duszyńska B; Kłodzińska A; Tatarczyńska E; Chojnacka-Wójcik E
    Bioorg Med Chem; 2005 Mar; 13(6):2293-303. PubMed ID: 15727878
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In-vivo effects of the 1,2,4-piperazine derivatives MM5 and MC1, putative 5-HT agonists, on dopamine and serotonin release in rat prefrontal cortex.
    Iskra-Jopa J; Gołembiowska K; Dziubina A; Cybulski M; Duszyńska B; Chilmonczyk Z
    J Pharm Pharmacol; 2005 Feb; 57(2):205-11. PubMed ID: 15720784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel benzothiazolin-2-one and benzoxazin-3-one arylpiperazine derivatives with mixed 5HT1A/D2 affinity as potential atypical antipsychotics.
    Taverne T; Diouf O; Depreux P; Poupaert JH; Lesieur D; Guardiola-Lemaître B; Renard P; Rettori MC; Caignard DH; Pfeiffer B
    J Med Chem; 1998 Jun; 41(12):2010-8. PubMed ID: 9622542
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents.
    Norman MH; Rigdon GC; Navas F; Cooper BR
    J Med Chem; 1994 Aug; 37(16):2552-63. PubMed ID: 7914539
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aminopyrimidines with high affinity for both serotonin and dopamine receptors.
    Wustrow D; Belliotti T; Glase S; Kesten SR; Johnson D; Colbry N; Rubin R; Blackburn A; Akunne H; Corbin A; Davis MD; Georgic L; Whetzel S; Zoski K; Heffner T; Pugsley T; Wise L
    J Med Chem; 1998 Feb; 41(5):760-71. PubMed ID: 9513604
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological characterization of alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazinebutanol and analogues as potential atypical antipsychotic agents.
    Yevich JP; New JS; Lobeck WG; Dextraze P; Bernstein E; Taylor DP; Yocca FD; Eison MS; Temple DL
    J Med Chem; 1992 Nov; 35(24):4516-25. PubMed ID: 1361578
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The impact of the halogen bonding on D
    Partyka A; Kurczab R; Canale V; Satała G; Marciniec K; Pasierb A; Jastrzębska-Więsek M; Pawłowski M; Wesołowska A; Bojarski AJ; Zajdel P
    Bioorg Med Chem; 2017 Jul; 25(14):3638-3648. PubMed ID: 28529043
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The thieno[3,2-c]pyridine and furo[3,2-c]pyridine rings: new pharmacophores with potential antipsychotic activity.
    New JS; Christopher WL; Yevich JP; Butler R; Schlemmer RF; VanderMaelen CP; Cipollina JA
    J Med Chem; 1989 Jun; 32(6):1147-56. PubMed ID: 2542551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-activity relationships of a series of substituted benzamides: potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents.
    Norman MH; Rigdon GC; Hall WR; Navas F
    J Med Chem; 1996 Mar; 39(5):1172-88. PubMed ID: 8676355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-affinity relationships of novel N-(1-ethyl-4-methylhexahydro-1,4-diazepin-6-yl)pyridine-3-carboxamides with potent serotonin 5-HT3 and dopamine D2 receptor antagonistic activity.
    Hirokawa Y; Fujiwara I; Suzuki K; Harada H; Yoshikawa T; Yoshida N; Kato S
    J Med Chem; 2003 Feb; 46(5):702-15. PubMed ID: 12593651
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.