BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

446 related articles for article (PubMed ID: 7481842)

  • 1. Gemcitabine: metabolism, mechanisms of action, and self-potentiation.
    Plunkett W; Huang P; Xu YZ; Heinemann V; Grunewald R; Gandhi V
    Semin Oncol; 1995 Aug; 22(4 Suppl 11):3-10. PubMed ID: 7481842
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Preclinical characteristics of gemcitabine.
    Plunkett W; Huang P; Gandhi V
    Anticancer Drugs; 1995 Dec; 6 Suppl 6():7-13. PubMed ID: 8718419
    [TBL] [Abstract][Full Text] [Related]  

  • 3. [Non-clinical studies of gemcitabine--the mode of action and antitumor activities].
    Tsukagoshi S
    Gan To Kagaku Ryoho; 1999 Feb; 26(3):393-400. PubMed ID: 10065109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cellular pharmacology of gemcitabine.
    Mini E; Nobili S; Caciagli B; Landini I; Mazzei T
    Ann Oncol; 2006 May; 17 Suppl 5():v7-12. PubMed ID: 16807468
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effects of gemcitabine and araC on in vitro DNA synthesis mediated by the human breast cell DNA synthesome.
    Jiang HY; Hickey RJ; Abdel-Aziz W; Malkas LH
    Cancer Chemother Pharmacol; 2000; 45(4):320-8. PubMed ID: 10755321
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells.
    Gandhi V; Mineishi S; Huang P; Yang Y; Chubb S; Chapman AJ; Nowak BJ; Hertel LW; Plunkett W
    Semin Oncol; 1995 Aug; 22(4 Suppl 11):61-7. PubMed ID: 7481847
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines.
    Bergman AM; Munch-Petersen B; Jensen PB; Sehested M; Veerman G; Voorn DA; Smid K; Pinedo HM; Peters GJ
    Biochem Pharmacol; 2001 Jun; 61(11):1401-8. PubMed ID: 11331076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of resistance to 2',2'-difluorodeoxycytidine in the human ovarian cancer cell line A2780.
    Ruiz van Haperen VW; Veerman G; Eriksson S; Stegmann AP; Peters GJ
    Semin Oncol; 1995 Aug; 22(4 Suppl 11):35-41. PubMed ID: 7481843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gemcitabine: preclinical pharmacology and mechanisms of action.
    Plunkett W; Huang P; Searcy CE; Gandhi V
    Semin Oncol; 1996 Oct; 23(5 Suppl 10):3-15. PubMed ID: 8893876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation.
    Heinemann V; Xu YZ; Chubb S; Sen A; Hertel LW; Grindey GB; Plunkett W
    Cancer Res; 1992 Feb; 52(3):533-9. PubMed ID: 1732039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preclinical, pharmacologic, and phase I studies of gemcitabine.
    Storniolo AM; Allerheiligen SR; Pearce HL
    Semin Oncol; 1997 Apr; 24(2 Suppl 7):S7-2-S7-7. PubMed ID: 9194473
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism.
    Heinemann V; Schulz L; Issels RD; Plunkett W
    Semin Oncol; 1995 Aug; 22(4 Suppl 11):11-8. PubMed ID: 7481839
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 2',2'-Difluoro-deoxycytidine (gemcitabine) incorporation into RNA and DNA of tumour cell lines.
    Ruiz van Haperen VW; Veerman G; Vermorken JB; Peters GJ
    Biochem Pharmacol; 1993 Aug; 46(4):762-6. PubMed ID: 8363650
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
    Huang P; Chubb S; Hertel LW; Grindey GB; Plunkett W
    Cancer Res; 1991 Nov; 51(22):6110-7. PubMed ID: 1718594
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetic studies on 2',2'-difluorodeoxycytidine (Gemcitabine) with purified human deoxycytidine kinase and cytidine deaminase.
    Bouffard DY; Laliberté J; Momparler RL
    Biochem Pharmacol; 1993 May; 45(9):1857-61. PubMed ID: 8494545
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Decreased resistance to gemcitabine (2',2'-difluorodeoxycitidine) of cytosine arabinoside-resistant myeloblastic murine and rat leukemia cell lines: role of altered activity and substrate specificity of deoxycytidine kinase.
    Bergman AM; Pinedo HM; Jongsma AP; Brouwer M; Ruiz van Haperen VW; Veerman G; Leyva A; Eriksson S; Peters GJ
    Biochem Pharmacol; 1999 Feb; 57(4):397-406. PubMed ID: 9933028
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Schedule dependence of sensitivity to 2',2'-difluorodeoxycytidine (Gemcitabine) in relation to accumulation and retention of its triphosphate in solid tumour cell lines and solid tumours.
    Ruiz van Haperen VW; Veerman G; Boven E; Noordhuis P; Vermorken JB; Peters GJ
    Biochem Pharmacol; 1994 Oct; 48(7):1327-39. PubMed ID: 7945430
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The synergistic interaction of gemcitabine and cytosine arabinoside with the ribonucleotide reductase inhibitor triapine is schedule dependent.
    Sigmond J; Kamphuis JA; Laan AC; Hoebe EK; Bergman AM; Peters GJ
    Biochem Pharmacol; 2007 May; 73(10):1548-57. PubMed ID: 17324380
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential effects of gemcitabine on ribonucleotide pools of twenty-one solid tumour and leukaemia cell lines.
    van Moorsel CJ; Bergman AM; Veerman G; Voorn DA; Ruiz van Haperen VW; Kroep JR; Pinedo HM; Peters GJ
    Biochim Biophys Acta; 2000 Mar; 1474(1):5-12. PubMed ID: 10699484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interference of gemcitabine triphosphate with the measurements of deoxynucleotides using an optimized DNA polymerase elongation assay.
    Smid K; Van Moorsel CJ; Noordhuis P; Voorn DA; Peters GJ
    Int J Oncol; 2001 Jul; 19(1):157-62. PubMed ID: 11408937
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.