148 related articles for article (PubMed ID: 7487870)
1. Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase.
Ponasik JA; Strickland C; Faerman C; Savvides S; Karplus PA; Ganem B
Biochem J; 1995 Oct; 311 ( Pt 2)(Pt 2):371-5. PubMed ID: 7487870
[TBL] [Abstract][Full Text] [Related]
2. Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors.
Faerman CH; Savvides SN; Strickland C; Breidenbach MA; Ponasik JA; Ganem B; Ripoll D; Krauth-Siegel RL; Karplus PA
Bioorg Med Chem; 1996 Aug; 4(8):1247-53. PubMed ID: 8879546
[TBL] [Abstract][Full Text] [Related]
3. Optimising inhibitors of trypanothione reductase using solid-phase chemistry.
Chitkul B; Bradley M
Bioorg Med Chem Lett; 2000 Oct; 10(20):2367-9. PubMed ID: 11055357
[TBL] [Abstract][Full Text] [Related]
4. Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents.
Li Z; Fennie MW; Ganem B; Hancock MT; Kobaslija M; Rattendi D; Bacchi CJ; O'Sullivan MC
Bioorg Med Chem Lett; 2001 Jan; 11(2):251-4. PubMed ID: 11206471
[TBL] [Abstract][Full Text] [Related]
5. Phenothiazine inhibitors of trypanothione reductase as potential antitrypanosomal and antileishmanial drugs.
Chan C; Yin H; Garforth J; McKie JH; Jaouhari R; Speers P; Douglas KT; Rock PJ; Yardley V; Croft SL; Fairlamb AH
J Med Chem; 1998 Jan; 41(2):148-56. PubMed ID: 9457238
[TBL] [Abstract][Full Text] [Related]
6. New spermine and spermidine derivatives as potent inhibitors of Trypanosoma cruzi trypanothione reductase.
Bonnet B; Soullez D; Davioud-Charvet E; Landry V; Horvath D; Sergheraert C
Bioorg Med Chem; 1997 Jul; 5(7):1249-56. PubMed ID: 9377084
[TBL] [Abstract][Full Text] [Related]
7. Polyamine derivatives as inhibitors of trypanothione reductase and assessment of their trypanocidal activities.
O'Sullivan MC; Zhou Q; Li Z; Durham TB; Rattendi D; Lane S; Bacchi CJ
Bioorg Med Chem; 1997 Dec; 5(12):2145-55. PubMed ID: 9459012
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals.
Cunningham ML; Zvelebil MJ; Fairlamb AH
Eur J Biochem; 1994 Apr; 221(1):285-95. PubMed ID: 8168518
[TBL] [Abstract][Full Text] [Related]
9. Dibenzosuberyl substituted polyamines and analogs of clomipramine as effective inhibitors of trypanothione reductase; molecular docking, and assessment of trypanocidal activities.
O'Sullivan MC; Durham TB; Valdes HE; Dauer KL; Karney NJ; Forrestel AC; Bacchi CJ; Baker JF
Bioorg Med Chem; 2015 Mar; 23(5):996-1010. PubMed ID: 25661449
[TBL] [Abstract][Full Text] [Related]
10. Inhibiting effects of spermidine derivatives on Trypanosoma cruzi trypanothione reductase.
O'Sullivan MC; Dalrymple DM; Zhou Q
J Enzyme Inhib; 1996 Oct; 11(2):97-114. PubMed ID: 9204399
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of trypanothione reductase by substrate analogues.
Garrard EA; Borman EC; Cook BN; Pike EJ; Alberg DG
Org Lett; 2000 Nov; 2(23):3639-42. PubMed ID: 11073664
[TBL] [Abstract][Full Text] [Related]
12. Benzofuranyl 3,5-bis-polyamine derivatives as time-dependent inhibitors of trypanothione reductase.
Hamilton CJ; Saravanamuthu A; Fairlamb AH; Eggleston IM
Bioorg Med Chem; 2003 Aug; 11(17):3683-93. PubMed ID: 12901914
[TBL] [Abstract][Full Text] [Related]
13. The synthesis and inhibitory activity of dethiotrypanothione and analogues against trypanothione reductase.
Czechowicz JA; Wilhelm AK; Spalding MD; Larson AM; Engel LK; Alberg DG
J Org Chem; 2007 May; 72(10):3689-93. PubMed ID: 17439174
[TBL] [Abstract][Full Text] [Related]
14. Trypanocidal bisbenzylisoquinoline alkaloids are inhibitors of trypanothione reductase.
Fournet A; Inchausti A; Yaluff G; Rojas De Arias A; Guinaudeau H; Bruneton J; Breidenbach MA; Karplus PA; Faerman CH
J Enzyme Inhib; 1998 Feb; 13(1):1-9. PubMed ID: 9879510
[TBL] [Abstract][Full Text] [Related]
15. Substrate specificity of the flavoprotein trypanothione disulfide reductase from Crithidia fasciculata.
Henderson GB; Fairlamb AH; Ulrich P; Cerami A
Biochemistry; 1987 Jun; 26(11):3023-7. PubMed ID: 3607007
[TBL] [Abstract][Full Text] [Related]
16. Molecular characterization of the trypanothione reductase gene from Crithidia fasciculata and Trypanosoma brucei: comparison with other flavoprotein disulphide oxidoreductases with respect to substrate specificity and catalytic mechanism.
Aboagye-Kwarteng T; Smith K; Fairlamb AH
Mol Microbiol; 1992 Nov; 6(21):3089-99. PubMed ID: 1453951
[TBL] [Abstract][Full Text] [Related]
17. Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
Jockers-Scherübl MC; Schirmer RH; Krauth-Siegel RL
Eur J Biochem; 1989 Mar; 180(2):267-72. PubMed ID: 2647489
[TBL] [Abstract][Full Text] [Related]
18. The glutamyl binding site of trypanothione reductase from Crithidia fasciculata: enzyme kinetic properties of gamma-glutamyl-modified substrate analogues.
el-Waer AF; Smith K; McKie JH; Benson T; Fairlamb AH; Douglas KT
Biochim Biophys Acta; 1993 Nov; 1203(1):93-8. PubMed ID: 8105896
[TBL] [Abstract][Full Text] [Related]
19. Specific peptide inhibitors of trypanothione reductase with backbone structures unrelated to that of substrate: potential rational drug design lead frameworks.
McKie JH; Garforth J; Jaouhari R; Chan C; Yin H; Besheya T; Fairlamb AH; Douglas KT
Amino Acids; 2001; 20(2):145-53. PubMed ID: 11332449
[TBL] [Abstract][Full Text] [Related]
20. Effect of polyamines on mitochondrial F-ATPase from Crithidia fasciculata and Trypanosoma cruzi.
Rilo MC; Stoppani AO
Biochem Mol Biol Int; 1993 Jan; 29(1):131-9. PubMed ID: 8490559
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
