These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

95 related articles for article (PubMed ID: 7487993)

  • 1. Effect of KN-62, Ca2+/calmodulin-dependent protein kinase II inhibitor, on adriamycin resistance of human ovarian cancer cells.
    Obata NH; Okazaki K; Maeda O; Kikkawa F; Tomoda Y; Hidaka H
    Biochem Biophys Res Commun; 1995 Oct; 215(2):566-71. PubMed ID: 7487993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of KN-62, Ca2+/calmodulin dependent protein kinase II inhibitor on cell cycle.
    Minami H; Inoue S; Hidaka H
    Biochem Biophys Res Commun; 1994 Feb; 199(1):241-8. PubMed ID: 8123019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of Ca2+/calmodulin-dependent protein kinase types II and IV, and reduced DNA synthesis due to the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenyl piperazine) in small cell lung carcinoma.
    Williams CL; Phelps SH; Porter RA
    Biochem Pharmacol; 1996 Mar; 51(5):707-15. PubMed ID: 8615909
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of voltage-gated Ca2+ channel activity in small cell lung carcinoma by the Ca2+/calmodulin-dependent protein kinase inhibitor KN-62 (1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperaz ine) .
    Williams CL; Porter RA; Phelps SH
    Biochem Pharmacol; 1995 Dec; 50(12):1979-85. PubMed ID: 8849323
    [TBL] [Abstract][Full Text] [Related]  

  • 5. KN-62, 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-tyrosyl]-4-phenylpiperazi ne, a specific inhibitor of Ca2+/calmodulin-dependent protein kinase II.
    Tokumitsu H; Chijiwa T; Hagiwara M; Mizutani A; Terasawa M; Hidaka H
    J Biol Chem; 1990 Mar; 265(8):4315-20. PubMed ID: 2155222
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of a new Ca2(+)-calmodulin-dependent protein kinase II inhibitor on GABA release in cerebrospinal fluid of the rat.
    Ishikawa N; Hashiba Y; Hidaka H
    J Pharmacol Exp Ther; 1990 Aug; 254(2):598-602. PubMed ID: 2384887
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ca(2+)/calmodulin-dependent protein kinase II inhibitor KN-62 inhibits adrenal medullary chromaffin cell functions independent of its action on the kinase.
    Tsutsui M; Yanagihara N; Fukunaga K; Minami K; Nakashima Y; Kuroiwa A; Miyamoto E; Izumi F
    J Neurochem; 1996 Jun; 66(6):2517-22. PubMed ID: 8632177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of voltage-gated Ca2+ channels and insulin secretion in HIT cells by the Ca2+/calmodulin-dependent protein kinase II inhibitor KN-62: comparison with antagonists of calmodulin and L-type Ca2+ channels.
    Li G; Hidaka H; Wollheim CB
    Mol Pharmacol; 1992 Sep; 42(3):489-8. PubMed ID: 1328847
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of regulated catecholamine secretion from PC12 cells by the Ca2+/calmodulin kinase II inhibitor KN-62.
    Schweitzer ES; Sanderson MJ; Wasterlain CG
    J Cell Sci; 1995 Jul; 108 ( Pt 7)():2619-28. PubMed ID: 7593303
    [TBL] [Abstract][Full Text] [Related]  

  • 10. KN-62, a specific Ca++/calmodulin-dependent protein kinase inhibitor, reversibly depresses the rate of beating of cultured fetal mouse cardiac myocytes.
    Okazaki K; Ishikawa T; Inui M; Tada M; Goshima K; Okamoto T; Hidaka H
    J Pharmacol Exp Ther; 1994 Sep; 270(3):1319-24. PubMed ID: 7932185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KN-62, a calcium/calmodulin-dependent protein kinase II inhibitor, inhibits high potassium-stimulated prolactin secretion and intracellular calcium increases in anterior pituitary cells.
    Cui ZJ; Hidaka H; Dannies PS
    Biochim Biophys Acta; 1996 Feb; 1310(3):343-7. PubMed ID: 8599613
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A newly synthesized bifunctional inhibitor, CKA1083, enhances adriamycin activity against human ovarian carcinoma cells.
    Maeda O; Kikkawa F; Tamakoshi K; Obata NH; Mizuno K; Suganuma N; Tomoda Y; Kuzuya K; Ishikawa T; Hidaka H
    Anticancer Res; 1997; 17(3C):1985-92. PubMed ID: 9216655
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of protein kinase inhibitors on morphology and function of cultured bovine adrenal chromaffin cells: KN-62 inhibits secretory function by blocking stimulated Ca2+ entry.
    Maurer JA; Wenger BW; McKay DB
    J Neurochem; 1996 Jan; 66(1):105-13. PubMed ID: 8522941
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of angiotensin II- and potassium-mediated aldosterone secretion by KN-62 suggests involvement of Ca(2+)-calmodulin dependent protein kinase II in aldosterone secretion.
    Ganguly A; Li L; Haxton M
    Biochem Biophys Res Commun; 1995 Apr; 209(3):916-20. PubMed ID: 7733984
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Tumor cell resistance to topoisomerase II poisons: role for intracellular free calcium in the sensitization by inhibitors or calcium-calmodulin-dependent enzymes.
    Grabowski DR; Dubyak GR; Rybicki L; Hidaka H; Ganapathi R
    Biochem Pharmacol; 1998 Aug; 56(3):345-9. PubMed ID: 9744572
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of insulin secretion by KN-62, a specific inhibitor of the multifunctional Ca2+/calmodulin-dependent protein kinase II.
    Wenham RM; Landt M; Walters SM; Hidaka H; Easom RA
    Biochem Biophys Res Commun; 1992 Nov; 189(1):128-33. PubMed ID: 1333187
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reversible phosphorylation as a controlling factor for sustaining calcium oscillations in HeLa cells: Involvement of calmodulin-dependent kinase II and a calyculin A-inhibitable phosphatase.
    Zhu DM; Tekle E; Chock PB; Huang CY
    Biochemistry; 1996 Jun; 35(22):7214-23. PubMed ID: 8679550
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of M3 muscarinic acetylcholine receptor-mediated Ca2+ influx and intracellular Ca2+ mobilization in neuroblastoma cells by the Ca2+/calmodulin-dependent protein kinase inhibitor 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-trosyl]-4-phenylpiperazin e (KN-62).
    Puhl HL; Raman PS; Williams CL; Aronstam RS
    Biochem Pharmacol; 1997 Apr; 53(8):1107-14. PubMed ID: 9175715
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A selective Ca2+/calmodulin-dependent protein kinase II inhibitor, KN-62, inhibits the enhanced phosphorylation and the activation of tyrosine hydroxylase by 56 mM K+ in rat pheochromocytoma PC12h cells.
    Ishii A; Kiuchi K; Kobayashi R; Sumi M; Hidaka H; Nagatsu T
    Biochem Biophys Res Commun; 1991 May; 176(3):1051-6. PubMed ID: 1674865
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A specific inhibitor of calcium/calmodulin-dependent protein kinase-II provides neuroprotection against NMDA- and hypoxia/hypoglycemia-induced cell death.
    Hajimohammadreza I; Probert AW; Coughenour LL; Borosky SA; Marcoux FW; Boxer PA; Wang KK
    J Neurosci; 1995 May; 15(5 Pt 2):4093-101. PubMed ID: 7538570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.