These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 7492546)

  • 1. An active site phenylalanine of 3-oxo-delta 5-steroid isomerase is catalytically important for proton transfer.
    Brothers PN; Blotny G; Qi L; Pollack RM
    Biochemistry; 1995 Nov; 34(47):15453-8. PubMed ID: 7492546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Catalytic contribution of phenylalanine-101 of 3-oxo-Delta 5-steroid isomerase.
    Qi L; Pollack RM
    Biochemistry; 1998 May; 37(19):6760-6. PubMed ID: 9578560
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Electrophilic assistance by Asp-99 of 3-oxo-Delta 5-steroid isomerase.
    Thornburg LD; Hénot F; Bash DP; Hawkinson DC; Bartel SD; Pollack RM
    Biochemistry; 1998 Jul; 37(29):10499-506. PubMed ID: 9671521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Catalytic activity of the D38A mutant of 3-oxo-Delta 5-steroid isomerase: recruitment of aspartate-99 as the base.
    Hénot F; Pollack RM
    Biochemistry; 2000 Mar; 39(12):3351-9. PubMed ID: 10727228
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Binding of 2-naphthols to D38E mutants of 3-oxo-Delta 5-steroid isomerase: variation of ligand ionization state with the nature of the electrophilic component.
    Petrounia IP; Blotny G; Pollack RM
    Biochemistry; 2000 Jan; 39(1):110-6. PubMed ID: 10625485
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reaction energetics of a mutant 3-oxo-delta 5-steroid isomerase with an altered active site base (D38E).
    Zawrotny ME; Pollack RM
    Biochemistry; 1994 Nov; 33(46):13896-902. PubMed ID: 7947798
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pseudoreversion of the catalytic activity of Y14F by the additional substitution(s) of tyrosine with phenylalanine in the hydrogen bond network of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
    Choi G; Ha NC; Kim MS; Hong BH; Oh BH; Choi KY
    Biochemistry; 2001 Jun; 40(23):6828-35. PubMed ID: 11389596
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substrate polarization by residues in delta 5-3-ketosteroid isomerase probed by site-directed mutagenesis and UV resonance Raman spectroscopy.
    Austin JC; Kuliopulos A; Mildvan AS; Spiro TG
    Protein Sci; 1992 Feb; 1(2):259-70. PubMed ID: 1339027
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase.
    Kuliopulos A; Mildvan AS; Shortle D; Talalay P
    Biochemistry; 1989 Jan; 28(1):149-59. PubMed ID: 2706241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nature of the intermediate in the 3-oxo-delta 5-steroid isomerase reaction.
    Zeng BF; Bounds PL; Steiner RF; Pollack RM
    Biochemistry; 1992 Feb; 31(5):1521-8. PubMed ID: 1346570
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanistic insights from the three-dimensional structure of 3-oxo-Delta(5)-steroid isomerase.
    Pollack RM; Thornburg LD; Wu ZR; Summers MF
    Arch Biochem Biophys; 1999 Oct; 370(1):9-15. PubMed ID: 10496971
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Crystal structure and enzyme mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas testosteroni.
    Cho HS; Choi G; Choi KY; Oh BH
    Biochemistry; 1998 Jun; 37(23):8325-30. PubMed ID: 9622484
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase.
    Jang DS; Choi G; Cha HJ; Shin S; Hong BH; Lee HJ; Lee HC; Choi KY
    Mol Cells; 2015 May; 38(5):409-15. PubMed ID: 25947291
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism of proton transfer in the isomerization of 5-androstene-3, 17-dione by 3-oxo-delta 5-steroid isomerase and its D38E mutant.
    Zawrotny ME; Hawkinson DC; Blotny G; Pollack RM
    Biochemistry; 1996 May; 35(20):6438-42. PubMed ID: 8639590
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Asp-99 donates a hydrogen bond not to Tyr-14 but to the steroid directly in the catalytic mechanism of Delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
    Choi G; Ha NC; Kim SW; Kim DH; Park S; Oh BH; Choi KY
    Biochemistry; 2000 Feb; 39(5):903-9. PubMed ID: 10653633
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
    Kim DH; Nam GH; Jang DS; Choi G; Joo S; Kim JS; Oh BH; Choi KY
    Biochemistry; 1999 Oct; 38(42):13810-9. PubMed ID: 10529226
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of the internal equilibrium constant for 3-oxo-delta 5-steroid isomerase using the D38E and D38N mutants: the energetic basis for catalysis.
    Hawkinson DC; Pollack RM; Ambulos NP
    Biochemistry; 1994 Oct; 33(40):12172-83. PubMed ID: 7918439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Energetics of 3-oxo-delta 5-steroid isomerase: source of the catalytic power of the enzyme.
    Hawkinson DC; Eames TC; Pollack RM
    Biochemistry; 1991 Nov; 30(45):10849-58. PubMed ID: 1932007
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.
    Nam GH; Cha SS; Yun YS; Oh YH; Hong BH; Lee HS; Choi KY
    Biochem J; 2003 Oct; 375(Pt 2):297-305. PubMed ID: 12852789
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Water in the active site of ketosteroid isomerase.
    Hanoian P; Hammes-Schiffer S
    Biochemistry; 2011 Aug; 50(31):6689-700. PubMed ID: 21710970
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.