These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 7493001)

  • 1. Conformational analysis of 19-oxygenated steroids with a 4-ene or 2,4-diene structure, potential intermediates of aromatase reaction, with semiempirical molecular orbital PM3 calculations.
    Numazawa M; Oshibe M
    Biol Pharm Bull; 1995 May; 18(5):782-4. PubMed ID: 7493001
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 1,4-addition reaction with thiols and conformational analysis with PM3 molecular orbital calculations of 19-oxygenated androst-4-ene-3,6,17-triones.
    Numazawa M; Oshibe M; Matsuzaki H
    Steroids; 1993 Sep; 58(9):423-8. PubMed ID: 8236328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Probing the binding pocket of the active site of aromatase with 6-ether or 6-ester substituted androst-4-ene-3,17-diones and their diene and triene analogs.
    Numazawa M; Shelangouski M; Nagasaka M
    Steroids; 2000 Dec; 65(12):871-82. PubMed ID: 11077085
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and structure-activity relationships of 6-substituted androst-4-ene analogs as aromatase inhibitors.
    Numazawa M; Kamiyama T; Tachibana M; Oshibe M
    J Med Chem; 1996 May; 39(11):2245-52. PubMed ID: 8667367
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group.
    Numazawa M; Oshibe M; Yamaguchi S; Tachibana M
    J Med Chem; 1996 Mar; 39(5):1033-8. PubMed ID: 8676338
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 19-oxygenated derivatives of androst-4-ene-6,17-dione and androst-5-ene-4,17-dione as catalytic probes for the active site of aromatase.
    Numazawa M; Yamada K; Kidokoro K
    Biol Pharm Bull; 1999 Oct; 22(10):1134-6. PubMed ID: 10549872
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 6-Alkylandrosta-4,6-diene-3,17-diones and their 1,4,6-triene analogs as aromatase inhibitors. Structure-activity relationships.
    Numazawa M; Oshibe M; Yamaguchi S
    Steroids; 1997; 62(8-9):595-602. PubMed ID: 9292934
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A time-dependent inactivation of aromatase by 19-oxygenated androst-4-ene-3,6,17-triones.
    Numazawa M; Mutsumi A; Hoshi K; Kigawa H; Oshibe M
    J Steroid Biochem Mol Biol; 1991 Dec; 39(6):959-66. PubMed ID: 1751396
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 6-Alkyl- and 6-arylandrost-4-ene-3,17-diones as aromatase inhibitors. Synthesis and structure-activity relationships.
    Numazawa M; Oshibe M
    J Med Chem; 1994 Apr; 37(9):1312-9. PubMed ID: 8176709
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biochemical studies of 16- or 19-substituted androst-4-enes as aromatase inhibitors.
    Numazawa M; Mutsumi A; Hoshi K; Oshibe M; Ishikawa E; Kigawa H
    J Med Chem; 1991 Aug; 34(8):2496-504. PubMed ID: 1875347
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Androst-5-ene-7,17-dione: a novel class of suicide substrate of aromatase.
    Numazawa M; Mutsumi A; Hoshi K; Tanaka Y
    Biochem Biophys Res Commun; 1992 Jul; 186(1):32-9. PubMed ID: 1632774
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Exploring new chemical functionalities to improve aromatase inhibition of steroids.
    Varela CL; Amaral C; Correia-da-Silva G; Costa SC; Carvalho RA; Costa G; Alcaro S; Teixeira NA; Tavares-da-Silva EJ; Roleira FM
    Bioorg Med Chem; 2016 Jun; 24(12):2823-31. PubMed ID: 27160054
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of 19-methyl substituted steroids and a proposal for the third aromatase monooxygenation.
    Covey DF; Carrell HL; Beusen DD
    Steroids; 1987; 50(4-6):363-74. PubMed ID: 3332933
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A- or B-ring-substituted derivatives of androst-4-ene-3,6,17-trione as aromatase inhibitors. Structure-activity relationships.
    Numazawa M; Tachibana M
    Steroids; 1994 Oct; 59(10):579-85. PubMed ID: 7878685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aromatase reaction of 3-deoxyandrogens: steric mode of the C-19 oxygenation and cleavage of the C10-C19 bond by human placental aromatase.
    Numazawa M; Nagaoka M; Sohtome N
    Biochemistry; 2005 Aug; 44(32):10839-45. PubMed ID: 16086586
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of androst-5-en-7-ones and androsta-3,5-dien-7-ones and their related 7-deoxy analogs as conformational and catalytic probes for the active site of aromatase.
    Numazawa M; Mutsumi A; Tachibana M; Hoshi K
    J Med Chem; 1994 Jul; 37(14):2198-205. PubMed ID: 8035427
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Studies directed towards a mechanistic evaluation of inactivation of aromatase by the suicide substrates androsta-1,4-diene-3,17-diones and its 6-ene derivatives aromatase inactivation by the 19-substituted derivatives and their enzymic aromatization.
    Numazawa M; Nagaoka M; Handa W; Ogawa Y; Matsuoka S
    J Steroid Biochem Mol Biol; 2007; 107(3-5):211-9. PubMed ID: 17656084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. C(10)-C(19) bond cleavage reaction of 19-oxygenated androst-4-ene-3,6-dione steroids under various conditions.
    Nagaoka M; Numazawa M
    Chem Pharm Bull (Tokyo); 2004 Aug; 52(8):983-5. PubMed ID: 15304996
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors.
    Cepa MM; Tavares da Silva EJ; Correia-da-Silva G; Roleira FM; Teixeira NA
    Steroids; 2008 Dec; 73(14):1409-15. PubMed ID: 18691607
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metabolism of 19-methyl-substituted steroids by human placental aromatase.
    Beusen DD; Carrell HL; Covey DF
    Biochemistry; 1987 Dec; 26(24):7833-41. PubMed ID: 3427108
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.