142 related articles for article (PubMed ID: 7495478)
1. Synthesis of podophyllotoxin congeners as potential DNA topoisomerase II inhibitors.
Kamal A; Atchison K; Daneshtalab M; Micetich RG
Anticancer Drug Des; 1995 Oct; 10(7):545-54. PubMed ID: 7495478
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
Kamal A; Gayatri NL; Reddy DR; Mohan Reddy PS; Arifuddin M; Dastidar SG; Kondapi AK; Rajkumar M
Bioorg Med Chem; 2005 Nov; 13(22):6218-25. PubMed ID: 16061385
[TBL] [Abstract][Full Text] [Related]
3. Linker length in podophyllotoxin-acridine conjugates determines potency in vivo and in vitro as well as specificity against MDR cell lines.
Rothenborg-Jensen L; Hansen HF; Wessel I; Nitiss JL; Schmidt G; Jensen PB; Sehested M; Jensen LH
Anticancer Drug Des; 2001 Dec; 16(6):305-15. PubMed ID: 12375883
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
Kamal A; Kumar BA; Suresh P; Agrawal SK; Chashoo G; Singh SK; Saxena AK
Bioorg Med Chem; 2010 Dec; 18(24):8493-500. PubMed ID: 21074444
[TBL] [Abstract][Full Text] [Related]
5. Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents.
Hu C; Xu D; Du W; Qian S; Wang L; Lou J; He Q; Yang B; Hu Y
Mol Biosyst; 2010 Feb; 6(2):410-20. PubMed ID: 20094661
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and topoisomerase II inhibition activity of 4'-demethylepipodophyllotoxin-lexitropsin conjugates.
Gupta R; al-Said NH; Oreski B; Lown JW
Anticancer Drug Des; 1996 Jun; 11(4):325-38. PubMed ID: 8679055
[TBL] [Abstract][Full Text] [Related]
7. Synthesis of a series of cytotoxic 2-acyl-1,2-dihydroellipticines which inhibit topoisomerase II.
Devraj R; Jurayj J; Fernandez JA; Barrett JF; Cushman M
Anticancer Drug Des; 1996 Jun; 11(4):311-24. PubMed ID: 8679054
[TBL] [Abstract][Full Text] [Related]
8. Syntheses and biological activities (topoisomerase inhibition and antitumor and antimicrobial properties) of rebeccamycin analogues bearing modified sugar moieties and substituted on the imide nitrogen with a methyl group.
Anizon F; Belin L; Moreau P; Sancelme M; Voldoire A; Prudhomme M; Ollier M; Sevère D; Riou JF; Bailly C; Fabbro D; Meyer T
J Med Chem; 1997 Oct; 40(21):3456-65. PubMed ID: 9341921
[TBL] [Abstract][Full Text] [Related]
9. Design of new topoisomerase II inhibitors based upon a quinobenzoxazine self-assembly model.
Zeng Q; Kwok Y; Kerwin SM; Mangold G; Hurley LH
J Med Chem; 1998 Oct; 41(22):4273-8. PubMed ID: 9784102
[TBL] [Abstract][Full Text] [Related]
10. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
Bailly C; Qu X; Chaires JB; Colson P; Houssier C; Ohkubo M; Nishimura S; Yoshinari T
J Med Chem; 1999 Jul; 42(15):2927-35. PubMed ID: 10425102
[TBL] [Abstract][Full Text] [Related]
11. Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
Duca M; Arimondo PB; Léonce S; Pierré A; Pfeiffer B; Monneret C; Dauzonne D
Org Biomol Chem; 2005 Mar; 3(6):1074-80. PubMed ID: 15750651
[TBL] [Abstract][Full Text] [Related]
12. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
Zhu XK; Guan J; Tachibana Y; Bastow KF; Cho SJ; Cheng HH; Cheng YC; Gurwith M; Lee KH
J Med Chem; 1999 Jul; 42(13):2441-6. PubMed ID: 10395485
[TBL] [Abstract][Full Text] [Related]
13. Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.
Cho SJ; Kashiwada Y; Bastow KF; Cheng YC; Lee KH
J Med Chem; 1996 Mar; 39(7):1396-402. PubMed ID: 8691469
[TBL] [Abstract][Full Text] [Related]
14. Design, synthesis, and biological evaluation of a series of fluoroquinoanthroxazines with contrasting dual mechanisms of action against topoisomerase II and G-quadruplexes.
Kim MY; Duan W; Gleason-Guzman M; Hurley LH
J Med Chem; 2003 Feb; 46(4):571-83. PubMed ID: 12570378
[TBL] [Abstract][Full Text] [Related]
15. Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
Kamal A; Kumar BA; Suresh P; Juvekar A; Zingde S
Bioorg Med Chem; 2011 May; 19(9):2975-9. PubMed ID: 21489802
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of novel podophyllotoxin analogs.
Li J; Hua HM; Tang YB; Zhang S; Ohkoshi E; Lee KH; Xiao Zy
Bioorg Med Chem Lett; 2012 Jul; 22(13):4293-5. PubMed ID: 22658864
[TBL] [Abstract][Full Text] [Related]
17. Antitumor activity of a novel podophyllotoxin derivative (TOP-53) against lung cancer and lung metastatic cancer.
Utsugi T; Shibata J; Sugimoto Y; Aoyagi K; Wierzba K; Kobunai T; Terada T; Oh-hara T; Tsuruo T; Yamada Y
Cancer Res; 1996 Jun; 56(12):2809-14. PubMed ID: 8665518
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and evaluation of psorospermin/quinobenzoxazine hybrids as structurally novel antitumor agents.
Kim MY; Na Y; Vankayalapati H; Gleason-Guzman M; Hurley LH
J Med Chem; 2003 Jul; 46(14):2958-72. PubMed ID: 12825936
[TBL] [Abstract][Full Text] [Related]
19. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.
Xiao Z; Bastow KF; Vance JR; Sidwell RS; Wang HK; Chen MS; Shi Q; Lee KH
J Med Chem; 2004 Oct; 47(21):5140-8. PubMed ID: 15456257
[TBL] [Abstract][Full Text] [Related]
20. Lycobetaine acts as a selective topoisomerase II beta poison and inhibits the growth of human tumour cells.
Barthelmes HU; Niederberger E; Roth T; Schulte K; Tang WC; Boege F; Fiebig HH; Eisenbrand G; Marko D
Br J Cancer; 2001 Nov; 85(10):1585-91. PubMed ID: 11720449
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
