BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 7500277)

  • 1. Enantiomeric resolution with a new chiral stationary phase of 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide, a cognition-enhancing benzothiadiazine derivative.
    Uzunov DP; Zivkovich I; Pirkle WH; Costa E; Guidotti A
    J Pharm Sci; 1995 Aug; 84(8):937-42. PubMed ID: 7500277
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 7-Chloro-3-methyl-3-4-dihydro-2H-1,2,4 benzothiadiazine S,S-dioxide (IDRA 21): a benzothiadiazine derivative that enhances cognition by attenuating DL-alpha-amino-2,3-dihydro-5-methyl-3-oxo-4-isoxazolepropanoic acid (AMPA) receptor desensitization.
    Zivkovic I; Thompson DM; Bertolino M; Uzunov D; DiBella M; Costa E; Guidotti A
    J Pharmacol Exp Ther; 1995 Jan; 272(1):300-9. PubMed ID: 7815345
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chiral resolution of the enantiomers of 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide using high-performance liquid chromatography on cellulose-based chiral stationary phases.
    Cannazza G; Braghiroli D; Baraldi M; Parenti C
    J Pharm Biomed Anal; 2000 Aug; 23(1):117-25. PubMed ID: 10898161
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Studies of enantiomerization of chiral 3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide type compounds.
    Cannazza G; Braghiroli D; Tait A; Baraldi M; Parenti C; Lindner W
    Chirality; 2001 Feb; 13(2):94-101. PubMed ID: 11170252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. On-line racemization by high-performance liquid chromatography.
    Cannazza G; Carrozzo MM; Battisti U; Braghiroli D; Parenti C
    J Chromatogr A; 2009 Jul; 1216(30):5655-9. PubMed ID: 19539938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide: a partial modulator of AMPA receptor desensitization devoid of neurotoxicity.
    Impagnatiello F; Oberto A; Longone P; Costa E; Guidotti A
    Proc Natl Acad Sci U S A; 1997 Jun; 94(13):7053-8. PubMed ID: 9192690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 7-Chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine S,S-dioxide (IDRA 21), a congener of aniracetam, potently abates pharmacologically induced cognitive impairments in patas monkeys.
    Thompson DM; Guidotti A; DiBella M; Costa E
    Proc Natl Acad Sci U S A; 1995 Aug; 92(17):7667-71. PubMed ID: 7644474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Liquid chromatographic resolution of 2-hydroxycarboxylic acids on a new chiral stationary phase derived from (S)-leucine.
    Hyun MH; Kang MH; Han SC
    J Chromatogr A; 2000 Jan; 868(1):31-9. PubMed ID: 10677077
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury.
    Yamada KA; Covey DF; Hsu CY; Hu R; Hu Y; He YY
    Ann Neurol; 1998 May; 43(5):664-9. PubMed ID: 9585363
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New fluorinated 1,2,4-benzothiadiazine 1,1-dioxides: discovery of an orally active cognitive enhancer acting through potentiation of the 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors.
    Francotte P; Goffin E; Fraikin P; Lestage P; Van Heugen JC; Gillotin F; Danober L; Thomas JY; Chiap P; Caignard DH; Pirotte B; de Tullio P
    J Med Chem; 2010 Feb; 53(4):1700-11. PubMed ID: 20108934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enantiomerization and hydrolysis of (+/-)-7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide by stopped-flow multidimensional high-performance liquid chromatography.
    Cannazza G; Carrozzo MM; Braghiroli D; Parenti C
    J Chromatogr A; 2008 Nov; 1212(1-2):41-7. PubMed ID: 18951549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. IDRA-21, a positive AMPA receptor modulator, inhibits synaptic and extrasynaptic NMDA receptor mediated events in cultured cerebellar granule cells.
    Losi G; Puia G; Braghiroli D; Baraldi M
    Neuropharmacology; 2004 Jun; 46(8):1105-13. PubMed ID: 15111017
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Enantiomers of benzothiadiazine diuretics by direct chromatographic resolution of the racemic drugs.
    Blaschke G; Maibaum J
    J Pharm Sci; 1985 Apr; 74(4):438-42. PubMed ID: 3999006
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enantiomerization of chiral 2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-c][1,2,4] benzothiadiazine 5,5-dioxide by stopped-flow multidimensional HPLC.
    Cannazza G; Carrozzo MM; Braghiroli D; Parenti C
    J Chromatogr B Analyt Technol Biomed Life Sci; 2008 Nov; 875(1):192-9. PubMed ID: 18515197
    [TBL] [Abstract][Full Text] [Related]  

  • 15. (S)-2,3-dihydro-[3,4]cyclopentano-1,2,4-benzothiadiazine-1,1-dioxide: (S18986-1) a positive modulator of AMPA receptors enhances (S)-AMPA-mediated [3H]noradrenaline release from rat hippocampal and frontal cortex slices.
    Lockhart B; Iop F; Closier M; Lestage P
    Eur J Pharmacol; 2000 Aug; 401(2):145-53. PubMed ID: 10924919
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Positive allosteric modulators of 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors belonging to 4-cyclopropyl-3,4-dihydro-2h-1,2,4-pyridothiadiazine dioxides and diversely chloro-substituted 4-cyclopropyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides.
    Francotte P; Nørholm AB; Deva T; Olsen L; Frydenvang K; Goffin E; Fraikin P; de Tullio P; Challal S; Thomas JY; Iop F; Louis C; Botez-Pop I; Lestage P; Danober L; Kastrup JS; Pirotte B
    J Med Chem; 2014 Nov; 57(22):9539-53. PubMed ID: 25375781
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elution order-absolute configuration relationship of K-region dihydrodiol enantiomers of benz[a]anthracene derivatives in chiral stationary phase high-performance liquid chromatography.
    Yang SK; Mushtaq M; Fu PP
    J Chromatogr; 1986 Dec; 371():195-209. PubMed ID: 3558546
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The diazoxide derivative 7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-S,S-dioxide augments AMPA- and GABA-mediated synaptic responses in cultured hippocampal neurons.
    Yamada KA; Hill MW; Hu Y; Covey DF
    Neurobiol Dis; 1998 Sep; 5(3):196-205. PubMed ID: 9848091
    [TBL] [Abstract][Full Text] [Related]  

  • 19. "Heart-cut" bidimensional achiral-chiral liquid chromatography applied to the evaluation of stereoselective metabolism, in vivo biological activity and brain response to chiral drug candidates targeting the central nervous system.
    Battisti UM; Citti C; Larini M; Ciccarella G; Stasiak N; Troisi L; Braghiroli D; Parenti C; Zoli M; Cannazza G
    J Chromatogr A; 2016 Apr; 1443():152-61. PubMed ID: 27020886
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular modeling studies, synthesis, configurational stability and biological activity of 8-chloro-2,3,5,6-tetrahydro-3,6-dimethyl-pyrrolo[1,2,3-de]-1,2,4-benzothiadiazine 1,1-dioxide.
    Battisti UM; Carrozzo MM; Cannazza G; Puia G; Troisi L; Braghiroli D; Parenti C; Jozwiak K
    Bioorg Med Chem; 2011 Dec; 19(23):7111-9. PubMed ID: 22019464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.