197 related articles for article (PubMed ID: 7502043)
1. Inhibitors of HIV nucleocapsid protein zinc fingers as candidates for the treatment of AIDS.
Rice WG; Supko JG; Malspeis L; Buckheit RW; Clanton D; Bu M; Graham L; Schaeffer CA; Turpin JA; Domagala J; Gogliotti R; Bader JP; Halliday SM; Coren L; Sowder RC; Arthur LO; Henderson LE
Science; 1995 Nov; 270(5239):1194-7. PubMed ID: 7502043
[TBL] [Abstract][Full Text] [Related]
2. The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities.
Tummino PJ; Harvey PJ; McQuade T; Domagala J; Gogliotti R; Sanchez J; Song Y; Hupe D
Antimicrob Agents Chemother; 1997 Feb; 41(2):394-400. PubMed ID: 9021197
[TBL] [Abstract][Full Text] [Related]
3. Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
Huang M; Maynard A; Turpin JA; Graham L; Janini GM; Covell DG; Rice WG
J Med Chem; 1998 Apr; 41(9):1371-81. PubMed ID: 9554870
[TBL] [Abstract][Full Text] [Related]
4. In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model.
Schito ML; Goel A; Song Y; Inman JK; Fattah RJ; Rice WG; Turpin JA; Sher A; Appella E
AIDS Res Hum Retroviruses; 2003 Feb; 19(2):91-101. PubMed ID: 12639244
[TBL] [Abstract][Full Text] [Related]
5. Inhibitors of human immunodeficiency virus type 1 zinc fingers prevent normal processing of gag precursors and result in the release of noninfectious virus particles.
Turpin JA; Terpening SJ; Schaeffer CA; Yu G; Glover CJ; Felsted RL; Sausville EA; Rice WG
J Virol; 1996 Sep; 70(9):6180-9. PubMed ID: 8709244
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.
Rice WG; Baker DC; Schaeffer CA; Graham L; Bu M; Terpening S; Clanton D; Schultz R; Bader JP; Buckheit RW; Field L; Singh PK; Turpin JA
Antimicrob Agents Chemother; 1997 Feb; 41(2):419-26. PubMed ID: 9021201
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of HIV-1 infectivity by zinc-ejecting aromatic C-nitroso compounds.
Rice WG; Schaeffer CA; Harten B; Villinger F; South TL; Summers MF; Henderson LE; Bess JW; Arthur LO; McDougal JS
Nature; 1993 Feb; 361(6411):473-5. PubMed ID: 8429889
[TBL] [Abstract][Full Text] [Related]
8. Benzamide-based thiolcarbamates: a new class of HIV-1 NCp7 inhibitors.
Goel A; Mazur SJ; Fattah RJ; Hartman TL; Turpin JA; Huang M; Rice WG; Appella E; Inman JK
Bioorg Med Chem Lett; 2002 Mar; 12(5):767-70. PubMed ID: 11858998
[TBL] [Abstract][Full Text] [Related]
9. The in vitro ejection of zinc from human immunodeficiency virus (HIV) type 1 nucleocapsid protein by disulfide benzamides with cellular anti-HIV activity.
Tummino PJ; Scholten JD; Harvey PJ; Holler TP; Maloney L; Gogliotti R; Domagala J; Hupe D
Proc Natl Acad Sci U S A; 1996 Feb; 93(3):969-73. PubMed ID: 8577770
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
[TBL] [Abstract][Full Text] [Related]
11. Inactivation of HIV-1 nucleocapsid protein P7 by pyridinioalkanoyl thioesters. Characterization of reaction products and proposed mechanism of action.
Basrur V; Song Y; Mazur SJ; Higashimoto Y; Turpin JA; Rice WG; Inman JK; Appella E
J Biol Chem; 2000 May; 275(20):14890-7. PubMed ID: 10809733
[TBL] [Abstract][Full Text] [Related]
12. Removal of zinc is required for processing of the mature nucleocapsid protein of human immunodeficiency virus, type 1, by the viral protease.
Wondrak EM; Sakaguchi K; Rice WG; Kun E; Kimmel AR; Louis JM
J Biol Chem; 1994 Sep; 269(35):21948-50. PubMed ID: 8071314
[TBL] [Abstract][Full Text] [Related]
13. Characterization of intermediates in the oxidation of zinc fingers in human immunodeficiency virus type 1 nucleocapsid protein P7.
Hathout Y; Fabris D; Han MS; Sowder RC; Henderson LE; Fenselau C
Drug Metab Dispos; 1996 Dec; 24(12):1395-400. PubMed ID: 8971148
[TBL] [Abstract][Full Text] [Related]
14. Biophysical characterization of zinc ejection from HIV nucleocapsid protein by anti-HIV 2,2'-dithiobis[benzamides] and benzisothiazolones.
Loo JA; Holler TP; Sanchez J; Gogliotti R; Maloney L; Reily MD
J Med Chem; 1996 Oct; 39(21):4313-20. PubMed ID: 8863808
[TBL] [Abstract][Full Text] [Related]
15. The role of nucleocapsid of HIV-1 in virus assembly.
Dawson L; Yu XF
Virology; 1998 Nov; 251(1):141-57. PubMed ID: 9813210
[TBL] [Abstract][Full Text] [Related]
16. Experimental determination and calculations of redox potential descriptors of compounds directed against retroviral zinc fingers: Implications for rational drug design.
Topol IA; McGrath C; Chertova E; Dasenbrock C; Lacourse WR; Eissenstat MA; Burt SK; Henderson LE; Casas-Finet JR
Protein Sci; 2001 Jul; 10(7):1434-45. PubMed ID: 11420445
[TBL] [Abstract][Full Text] [Related]
17. Specific disulfide formation in the oxidation of HIV-1 zinc finger protein nucleocapsid p7.
Yu X; Hathout Y; Fenselau C; Sowder RC; Henderson LE; Rice WG; Mendeleyev J; Kun E
Chem Res Toxicol; 1995 Jun; 8(4):586-90. PubMed ID: 7548739
[TBL] [Abstract][Full Text] [Related]
18. The site of antiviral action of 3-nitrosobenzamide on the infectivity process of human immunodeficiency virus in human lymphocytes.
Rice WG; Schaeffer CA; Graham L; Bu M; McDougal JS; Orloff SL; Villinger F; Young M; Oroszlan S; Fesen MR
Proc Natl Acad Sci U S A; 1993 Oct; 90(20):9721-4. PubMed ID: 7692451
[TBL] [Abstract][Full Text] [Related]
19. Zinc ejection as a new rationale for the use of cystamine and related disulfide-containing antiviral agents in the treatment of AIDS.
McDonnell NB; De Guzman RN; Rice WG; Turpin JA; Summers MF
J Med Chem; 1997 Jun; 40(13):1969-76. PubMed ID: 9207937
[TBL] [Abstract][Full Text] [Related]
20. A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.
Druillennec S; Dong CZ; Escaich S; Gresh N; Bousseau A; Roques BP; FourniƩ-Zaluski MC
Proc Natl Acad Sci U S A; 1999 Apr; 96(9):4886-91. PubMed ID: 10220388
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]