144 related articles for article (PubMed ID: 7503782)
1. Antitumour effects of pure diastereoisomers of 5-formyltetrahydrofolate in hepatic transplants of a rodent colon carcinoma model.
Carlsson G; Gustavsson B; Frösing R; Odin E; Hafström LO; Spears CP; Larsson PA
Biochem Pharmacol; 1995 Oct; 50(9):1347-51. PubMed ID: 7503782
[TBL] [Abstract][Full Text] [Related]
2. Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
van der Wilt CL; Backus HH; Smid K; Comijn L; Veerman G; Wouters D; Voorn DA; Priest DG; Bunni MA; Mitchell F; Jackman AL; Jansen G; Peters GJ
Cancer Res; 2001 May; 61(9):3675-81. PubMed ID: 11325838
[TBL] [Abstract][Full Text] [Related]
3. 5-Ethynyluracil (776C85): modulation of 5-fluorouracil efficacy and therapeutic index in rats bearing advanced colorectal carcinoma.
Cao S; Rustum YM; Spector T
Cancer Res; 1994 Mar; 54(6):1507-10. PubMed ID: 8137256
[TBL] [Abstract][Full Text] [Related]
4. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
[TBL] [Abstract][Full Text] [Related]
5. Accumulation of tetrahydrofolates in human plasma after leucovorin administration.
Bunni MA; Rembiesa BM; Priest DG; Sahovic E; Stuart R
Cancer Chemother Pharmacol; 1989; 23(6):353-7. PubMed ID: 2785439
[TBL] [Abstract][Full Text] [Related]
6. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
Spears CP; Shahinian AH; Moran RG; Heidelberger C; Corbett TH
Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
[TBL] [Abstract][Full Text] [Related]
7. Determinants of cytotoxicity with prolonged exposure to fluorouracil in human colon cancer cells.
Ren Q; Van Groeningen CJ; Hardcastle A; Aherne GW; Geoffroy F; Allegra CJ; Johnston PG; Grem JL
Oncol Res; 1997; 9(2):77-88. PubMed ID: 9167189
[TBL] [Abstract][Full Text] [Related]
8. Overview: rational basis for development of fluoropyrimidine/5-formyltetrahydrofolate combination chemotherapy.
Huennekens FM; Montejano YD; Vitols KS
Adv Exp Med Biol; 1988; 244():1-11. PubMed ID: 3073650
[TBL] [Abstract][Full Text] [Related]
9. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
[TBL] [Abstract][Full Text] [Related]
10. Enhanced antitumor activity of 5-fluorouracil in combination with 2'-deoxyinosine in human colorectal cell lines and human colon tumor xenografts.
Ciccolini J; Peillard L; Evrard A; Cuq P; Aubert C; Pelegrin A; Formento P; Milano G; Catalin J
Clin Cancer Res; 2000 Apr; 6(4):1529-35. PubMed ID: 10778986
[TBL] [Abstract][Full Text] [Related]
11. Metabolic basis of the synergistic antitumor activities of 5-fluorouracil and cisplatin in rodent tumor models in vivo.
Shirasaka T; Shimamoto Y; Ohshimo H; Saito H; Fukushima M
Cancer Chemother Pharmacol; 1993; 32(3):167-72. PubMed ID: 8500219
[TBL] [Abstract][Full Text] [Related]
12. Potentiation of the antitumor activity of 5-fluorouracil in colon carcinoma cells by the combination of interferon and deoxyribonucleosides results from complementary effects on thymidine phosphorylase.
Schwartz EL; Baptiste N; O'Connor CJ; Wadler S; Otter BA
Cancer Res; 1994 Mar; 54(6):1472-8. PubMed ID: 8137250
[TBL] [Abstract][Full Text] [Related]
13. Cytotoxic synergism of methioninase in combination with 5-fluorouracil and folinic acid.
Machover D; Zittoun J; Broët P; Metzger G; Orrico M; Goldschmidt E; Schilf A; Tonetti C; Tan Y; Delmas-Marsalet B; Luccioni C; Falissard B; Hoffman RM
Biochem Pharmacol; 2001 Apr; 61(7):867-76. PubMed ID: 11274973
[TBL] [Abstract][Full Text] [Related]
14. Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil.
Peters GJ; van der Wilt CL; van Groeningen CJ; Smid K; Meijer S; Pinedo HM
J Clin Oncol; 1994 Oct; 12(10):2035-42. PubMed ID: 7931471
[TBL] [Abstract][Full Text] [Related]
15. Locus of the interaction among 5-fluorouracil, leucovorin, and interferon-alpha 2a in colon carcinoma cells.
Houghton JA; Morton CL; Adkins DA; Rahman A
Cancer Res; 1993 Sep; 53(18):4243-50. PubMed ID: 8364921
[TBL] [Abstract][Full Text] [Related]
16. The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts.
Houghton JA; Schmidt C; Houghton PJ
Eur J Cancer Clin Oncol; 1982 Apr; 18(4):347-54. PubMed ID: 6889511
[TBL] [Abstract][Full Text] [Related]
17. Antitumour activity, toxicity and inhibition of thymidylate synthase of prolonged administration of 5-fluorouracil in mice.
Codacci-Pisanelli G; van der Wilt CL; Pinedo HM; Franchi F; Noordhuis P; Braakhuis BJ; van Laar JA; Peters GJ
Eur J Cancer; 1995; 31A(9):1517-25. PubMed ID: 7577082
[TBL] [Abstract][Full Text] [Related]
18. Relationship between dose rate of [6RS]Leucovorin administration, plasma concentrations of reduced folates, and pools of 5,10-methylenetetrahydrofolates and tetrahydrofolates in human colon adenocarcinoma xenografts.
Houghton JA; Williams LG; de Graaf SS; Cheshire PJ; Rodman JH; Maneval DC; Wainer IW; Jadaud P; Houghton PJ
Cancer Res; 1990 Jun; 50(12):3493-502. PubMed ID: 2140289
[TBL] [Abstract][Full Text] [Related]
19. Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil.
Berger SH; Hakala MT
Mol Pharmacol; 1984 Mar; 25(2):303-9. PubMed ID: 6608049
[TBL] [Abstract][Full Text] [Related]
20. Tumor size and origin determine the antitumor activity of cisplatin or 5-fluorouracil and its modulation by leucovorin in murine colon carcinomas.
Van Laar JA; Rustum YM; Van der Wilt CL; Smid K; Kuiper CM; Pinedo HM; Peters GJ
Cancer Chemother Pharmacol; 1996; 39(1-2):79-89. PubMed ID: 8995503
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]