BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

376 related articles for article (PubMed ID: 7508380)

  • 1. Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface.
    Molloy SS; Thomas L; VanSlyke JK; Stenberg PE; Thomas G
    EMBO J; 1994 Jan; 13(1):18-33. PubMed ID: 7508380
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin.
    Schäfer W; Stroh A; Berghöfer S; Seiler J; Vey M; Kruse ML; Kern HF; Klenk HD; Garten W
    EMBO J; 1995 Jun; 14(11):2424-35. PubMed ID: 7781597
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.
    Takahashi S; Nakagawa T; Banno T; Watanabe T; Murakami K; Nakayama K
    J Biol Chem; 1995 Nov; 270(47):28397-401. PubMed ID: 7499343
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Endoproteolytic cleavage of its propeptide is a prerequisite for efficient transport of furin out of the endoplasmic reticulum.
    Creemers JW; Vey M; Schäfer W; Ayoubi TA; Roebroek AJ; Klenk HD; Garten W; Van de Ven WJ
    J Biol Chem; 1995 Feb; 270(6):2695-702. PubMed ID: 7852339
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ordered and compartment-specfific autoproteolytic removal of the furin intramolecular chaperone is required for enzyme activation.
    Anderson ED; Molloy SS; Jean F; Fei H; Shimamura S; Thomas G
    J Biol Chem; 2002 Apr; 277(15):12879-90. PubMed ID: 11799113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracellular trafficking of furin is modulated by the phosphorylation state of a casein kinase II site in its cytoplasmic tail.
    Jones BG; Thomas L; Molloy SS; Thulin CD; Fry MD; Walsh KA; Thomas G
    EMBO J; 1995 Dec; 14(23):5869-83. PubMed ID: 8846780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The PC6B cytoplasmic domain contains two acidic clusters that direct sorting to distinct trans-Golgi network/endosomal compartments.
    Xiang Y; Molloy SS; Thomas L; Thomas G
    Mol Biol Cell; 2000 Apr; 11(4):1257-73. PubMed ID: 10749928
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.
    Liu G; Thomas L; Warren RA; Enns CA; Cunningham CC; Hartwig JH; Thomas G
    J Cell Biol; 1997 Dec; 139(7):1719-33. PubMed ID: 9412467
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Maturation of the trans-Golgi network protease furin: compartmentalization of propeptide removal, substrate cleavage, and COOH-terminal truncation.
    Vey M; Schäfer W; Berghöfer S; Klenk HD; Garten W
    J Cell Biol; 1994 Dec; 127(6 Pt 2):1829-42. PubMed ID: 7806563
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of membrane-type matrix metalloproteinase 3 zymogen by the proprotein convertase furin in the trans-Golgi network.
    Kang T; Nagase H; Pei D
    Cancer Res; 2002 Feb; 62(3):675-81. PubMed ID: 11830519
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of human furin precursor processing endoprotease occurs by an intramolecular autoproteolytic cleavage.
    Leduc R; Molloy SS; Thorne BA; Thomas G
    J Biol Chem; 1992 Jul; 267(20):14304-8. PubMed ID: 1629222
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endosome to trans-Golgi network transport of Proprotein Convertase 7 is mediated by a cluster of basic amino acids and palmitoylated cysteines.
    Declercq J; Ramos-Molina B; Sannerud R; Brouwers B; Pruniau VPEG; Meulemans S; Plets E; Annaert W; Creemers JWM
    Eur J Cell Biol; 2017 Aug; 96(5):432-439. PubMed ID: 28413120
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Retrieval of TGN proteins from the cell surface requires endosomal acidification.
    Chapman RE; Munro S
    EMBO J; 1994 May; 13(10):2305-12. PubMed ID: 8194522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans-Golgi network localization and internalization from the cell surface.
    Voorhees P; Deignan E; van Donselaar E; Humphrey J; Marks MS; Peters PJ; Bonifacino JS
    EMBO J; 1995 Oct; 14(20):4961-75. PubMed ID: 7588625
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways.
    Mallet WG; Maxfield FR
    J Cell Biol; 1999 Jul; 146(2):345-59. PubMed ID: 10465644
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of the furin endoprotease is a multiple-step process: requirements for acidification and internal propeptide cleavage.
    Anderson ED; VanSlyke JK; Thulin CD; Jean F; Thomas G
    EMBO J; 1997 Apr; 16(7):1508-18. PubMed ID: 9130696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A tyrosine-based motif and a casein kinase II phosphorylation site regulate the intracellular trafficking of the varicella-zoster virus glycoprotein I, a protein localized in the trans-Golgi network.
    Alconada A; Bauer U; Hoflack B
    EMBO J; 1996 Nov; 15(22):6096-110. PubMed ID: 8947032
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Basolateral sorting of furin in MDCK cells requires a phenylalanine-isoleucine motif together with an acidic amino acid cluster.
    Simmen T; Nobile M; Bonifacino JS; Hunziker W
    Mol Cell Biol; 1999 Apr; 19(4):3136-44. PubMed ID: 10082580
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shedding of membrane type matrix metalloproteinase 5 by a furin-type convertase: a potential mechanism for down-regulation.
    Wang X; Pei D
    J Biol Chem; 2001 Sep; 276(38):35953-60. PubMed ID: 11470782
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments.
    Wouters S; Leruth M; Decroly E; Vandenbranden M; Creemers JW; van de Loo JW; Ruysschaert JM; Courtoy PJ
    Biochem J; 1998 Dec; 336 ( Pt 2)(Pt 2):311-6. PubMed ID: 9820806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.