BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

296 related articles for article (PubMed ID: 7509634)

  • 21. [Studies of the resistance of the human immunodeficiency virus to azidothymidine. I. Kinetic studies of the interaction between reverse transcriptase and a series of its mutant forms with substrates and azidothymidine-5'-trisphosphate].
    Pokholok DK; Gudima SO; Esipov DS; Dobrynin VN; Memelova LV; Rechinskiĭ VO; Kochetkov SN
    Biokhimiia; 1994 May; 59(5):739-47. PubMed ID: 7519060
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Phenotypic mechanism of HIV-1 resistance to 3'-azido-3'-deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase.
    Arion D; Kaushik N; McCormick S; Borkow G; Parniak MA
    Biochemistry; 1998 Nov; 37(45):15908-17. PubMed ID: 9843396
    [TBL] [Abstract][Full Text] [Related]  

  • 23. AZT resistance of simian foamy virus reverse transcriptase is based on the excision of AZTMP in the presence of ATP.
    Hartl MJ; Kretzschmar B; Frohn A; Nowrouzi A; Rethwilm A; Wöhrl BM
    Nucleic Acids Res; 2008 Feb; 36(3):1009-16. PubMed ID: 18096624
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cytotoxicity of 3'-azido-3'-deoxythymidine correlates with 3'-azidothymidine-5'-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3'-azidothymidine-5'-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells.
    Törnevik Y; Ullman B; Balzarini J; Wahren B; Eriksson S
    Biochem Pharmacol; 1995 Mar; 49(6):829-37. PubMed ID: 7702641
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Nucleoside drug resistance in HIV-1 reverse transcriptase.
    Yadav PN; Yadav JS; Modak MJ
    Nat Struct Biol; 1995 Mar; 2(3):193-5. PubMed ID: 7539709
    [No Abstract]   [Full Text] [Related]  

  • 26. The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer.
    Selmi B; Deval J; Alvarez K; Boretto J; Sarfati S; Guerreiro C; Canard B
    J Biol Chem; 2003 Oct; 278(42):40464-72. PubMed ID: 12902345
    [TBL] [Abstract][Full Text] [Related]  

  • 27. 3'-Azido-3',5'-dideoxythymidine-5'-methylphosphonic acid diphosphate: synthesis and HIV-1 reverse transcriptase inhibition.
    Freeman GA; Rideout JL; Miller WH; Reardon JE
    J Med Chem; 1992 Aug; 35(17):3192-6. PubMed ID: 1380561
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
    Ueno T; Shirasaka T; Mitsuya H
    J Biol Chem; 1995 Oct; 270(40):23605-11. PubMed ID: 7559526
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Effects of the Delta67 complex of mutations in human immunodeficiency virus type 1 reverse transcriptase on nucleoside analog excision.
    Boyer PL; Imamichi T; Sarafianos SG; Arnold E; Hughes SH
    J Virol; 2004 Sep; 78(18):9987-97. PubMed ID: 15331732
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
    Periclou AP; Nandy P; Avramis VI
    In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human immunodeficiency virus reverse transcriptase: steady-state and pre-steady-state kinetics of nucleotide incorporation.
    Reardon JE
    Biochemistry; 1992 May; 31(18):4473-9. PubMed ID: 1374638
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Inhibitory effect of N3-methyl derivative of 3'-azido-3'-deoxythymidine 5'-triphosphate on the activity of HIV-1 reverse transcriptase.
    Nakane H; Suzuki A; Nakata Y; Kitade Y; Hirota K; Maki Y; Ono K
    Nucleic Acids Symp Ser; 1991; (25):27-8. PubMed ID: 1726810
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Inhibition of human immunodeficiency virus 1 reverse transcriptase by 3'-azidothymidine triphosphate.
    Heidenreich O; Kruhøffer M; Grosse F; Eckstein F
    Eur J Biochem; 1990 Sep; 192(3):621-5. PubMed ID: 1698626
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of the initiation of HIV-1 reverse transcription by 3'-azido-3'-deoxythymidine. Comparison with elongation.
    Rigourd M; Lanchy JM; Le Grice SF; Ehresmann B; Ehresmann C; Marquet R
    J Biol Chem; 2000 Sep; 275(35):26944-51. PubMed ID: 10864929
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structural basis of HIV-1 resistance to AZT by excision.
    Tu X; Das K; Han Q; Bauman JD; Clark AD; Hou X; Frenkel YV; Gaffney BL; Jones RA; Boyer PL; Hughes SH; Sarafianos SG; Arnold E
    Nat Struct Mol Biol; 2010 Oct; 17(10):1202-9. PubMed ID: 20852643
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.
    Lennerstrand J; Hertogs K; Stammers DK; Larder BA
    J Virol; 2001 Aug; 75(15):7202-5. PubMed ID: 11435603
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs.
    White EL; Parker WB; Ross LJ; Shannon WM
    Antiviral Res; 1993 Dec; 22(4):295-308. PubMed ID: 7506513
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs.
    Parker WB; White EL; Shaddix SC; Ross LJ; Buckheit RW; Germany JM; Secrist JA; Vince R; Shannon WM
    J Biol Chem; 1991 Jan; 266(3):1754-62. PubMed ID: 1703154
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication.
    Caliendo AM; Savara A; An D; DeVore K; Kaplan JC; D'Aquila RT
    J Virol; 1996 Apr; 70(4):2146-53. PubMed ID: 8642636
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.
    Chen MS; Suttmann RT; Papp E; Cannon PD; McRoberts MJ; Bach C; Copeland WC; Wang TS
    Biochemistry; 1993 Jun; 32(23):6002-10. PubMed ID: 7685186
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 15.