These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. Increasing expression of the normal human CFTR cDNA in cystic fibrosis epithelial cells results in a progressive increase in the level of CFTR protein expression, but a limit on the level of cAMP-stimulated chloride secretion. Rosenfeld MA; Rosenfeld SJ; Danel C; Banks TC; Crystal RG Hum Gene Ther; 1994 Sep; 5(9):1121-9. PubMed ID: 7530494 [TBL] [Abstract][Full Text] [Related]
6. In vivo nasal potential difference: techniques and protocols for assessing efficacy of gene transfer in cystic fibrosis. Knowles MR; Paradiso AM; Boucher RC Hum Gene Ther; 1995 Apr; 6(4):445-55. PubMed ID: 7542031 [TBL] [Abstract][Full Text] [Related]
7. Induction of a cAMP-stimulated chloride secretion in regenerating poorly differentiated airway epithelial cells by adenovirus-mediated CFTR gene transfer. Dupuit F; Chinet T; Zahm JM; Pierrot D; Hinnrasky J; Kaplan H; Bonnet N; Puchelle E Hum Gene Ther; 1997 Aug; 8(12):1439-50. PubMed ID: 9287144 [TBL] [Abstract][Full Text] [Related]
9. In vitro assessment of variables affecting the efficiency and efficacy of adenovirus-mediated gene transfer to cystic fibrosis airway epithelia. Johnson LG; Pickles RJ; Boyles SE; Morris JC; Ye H; Zhou Z; Olsen JC; Boucher RC Hum Gene Ther; 1996 Jan; 7(1):51-9. PubMed ID: 8825868 [TBL] [Abstract][Full Text] [Related]
10. Gene transfer to freshly isolated human respiratory epithelial cells in vitro using a replication-deficient adenovirus containing the human cystic fibrosis transmembrane conductance regulator cDNA. Rosenfeld MA; Chu CS; Seth P; Danel C; Banks T; Yoneyama K; Yoshimura K; Crystal RG Hum Gene Ther; 1994 Mar; 5(3):331-42. PubMed ID: 7517189 [TBL] [Abstract][Full Text] [Related]
11. Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill. Boucher RC; Knowles MR; Johnson LG; Olsen JC; Pickles R; Wilson JM; Engelhardt J; Yang Y; Grossman M Hum Gene Ther; 1994 May; 5(5):615-39. PubMed ID: 7519885 [TBL] [Abstract][Full Text] [Related]
12. Restoration of cyclic adenosine monophosphate-stimulated chloride channel activity in human cystic fibrosis tracheobronchial submucosal gland cells by adenovirus-mediated and cationic lipid-mediated gene transfer. Jiang C; Finkbeiner WE; Widdicombe JH; Fang SL; Wang KX; Nietupski JB; Hehir KM; Cheng SH Am J Respir Cell Mol Biol; 1999 Jun; 20(6):1107-15. PubMed ID: 10340929 [TBL] [Abstract][Full Text] [Related]
13. Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans. Grubb BR; Pickles RJ; Ye H; Yankaskas JR; Vick RN; Engelhardt JF; Wilson JM; Johnson LG; Boucher RC Nature; 1994 Oct; 371(6500):802-6. PubMed ID: 7523956 [TBL] [Abstract][Full Text] [Related]
14. Development and analysis of recombinant adenoviruses for gene therapy of cystic fibrosis. Rich DP; Couture LA; Cardoza LM; Guiggio VM; Armentano D; Espino PC; Hehir K; Welsh MJ; Smith AE; Gregory RJ Hum Gene Ther; 1993 Aug; 4(4):461-76. PubMed ID: 7691187 [TBL] [Abstract][Full Text] [Related]
15. Adenovirus-mediated gene transfer transiently corrects the chloride transport defect in nasal epithelia of patients with cystic fibrosis. Zabner J; Couture LA; Gregory RJ; Graham SM; Smith AE; Welsh MJ Cell; 1993 Oct; 75(2):207-16. PubMed ID: 7691415 [TBL] [Abstract][Full Text] [Related]
16. A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis. Knowles MR; Hohneker KW; Zhou Z; Olsen JC; Noah TL; Hu PC; Leigh MW; Engelhardt JF; Edwards LJ; Jones KR N Engl J Med; 1995 Sep; 333(13):823-31. PubMed ID: 7544439 [TBL] [Abstract][Full Text] [Related]
17. Modification of nasal epithelial potential differences of individuals with cystic fibrosis consequent to local administration of a normal CFTR cDNA adenovirus gene transfer vector. Hay JG; McElvaney NG; Herena J; Crystal RG Hum Gene Ther; 1995 Nov; 6(11):1487-96. PubMed ID: 8573621 [TBL] [Abstract][Full Text] [Related]
18. Repeat administration of an adenovirus vector encoding cystic fibrosis transmembrane conductance regulator to the nasal epithelium of patients with cystic fibrosis. Zabner J; Ramsey BW; Meeker DP; Aitken ML; Balfour RP; Gibson RL; Launspach J; Moscicki RA; Richards SM; Standaert TA J Clin Invest; 1996 Mar; 97(6):1504-11. PubMed ID: 8617884 [TBL] [Abstract][Full Text] [Related]
19. Ability of a chimeric cAMP-responsive promoter to confer pharmacologic control of CFTR cDNA expression and cAMP-mediated Cl- secretion. Suzuki M; Singh RN; Crystal RG Gene Ther; 1997 Nov; 4(11):1195-201. PubMed ID: 9425443 [TBL] [Abstract][Full Text] [Related]