BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 7525959)

  • 1. Inhibition of topoisomerase II catalytic activity by pyridoacridine alkaloids from a Cystodytes sp. ascidian: a mechanism for the apparent intercalator-induced inhibition of topoisomerase II.
    McDonald LA; Eldredge GS; Barrows LR; Ireland CM
    J Med Chem; 1994 Oct; 37(22):3819-27. PubMed ID: 7525959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Additional cytotoxic pyridoacridine alkaloids from the ascidian Cystodytes violatinctus and biogenetic considerations.
    Bontemps N; Gattacceca F; Long C; Thomas OP; Banaigs B
    J Nat Prod; 2013 Sep; 76(9):1801-5. PubMed ID: 23961991
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sebastianines A and B, novel biologically active pyridoacridine alkaloids from the Brazilian ascidian Cystodytes dellechiajei.
    Torres YR; Bugni TS; Berlinck RG; Ireland CM; Magalhães A; Ferreira AG; Moreira Da Rocha R
    J Org Chem; 2002 Jul; 67(15):5429-32. PubMed ID: 12126446
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structures and antimicrobial activities of pyridoacridine alkaloids isolated from different chromotypes of the ascidian Cystodytes dellechiajei.
    Bontemps N; Bry D; López-Legentil S; Simon-Levert A; Long C; Banaigs B
    J Nat Prod; 2010 Jun; 73(6):1044-8. PubMed ID: 20491501
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyrroloquinoline and pyridoacridine alkaloids from marine sources.
    Ding Q; Chichak K; Lown JW
    Curr Med Chem; 1999 Jan; 6(1):1-27. PubMed ID: 9873113
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AK37: the first pyridoacridine described capable of stabilizing the topoisomerase I cleavable complex.
    Marshall KM; Holden JA; Koller A; Kashman Y; Copp BR; Barrows LR
    Anticancer Drugs; 2004 Oct; 15(9):907-13. PubMed ID: 15457132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of strong DNA-intercalating bioreductive compounds with topoisomerases I and II.
    Rosenzweig HS; Papadopoulou MV; Bloomer WD
    Oncol Res; 2005; 15(4):219-31. PubMed ID: 17822282
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The antileukemic alkaloid fagaronine is an inhibitor of DNA topoisomerases I and II.
    Larsen AK; Grondard L; Couprie J; Desoize B; Comoe L; Jardillier JC; Riou JF
    Biochem Pharmacol; 1993 Oct; 46(8):1403-12. PubMed ID: 8240389
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nordehydrocyclodercitin, a hexacyclic pyridoacridine alkaloid from the marine ascidian, Aplidium sp.
    Agrawal MS; Bowden BF
    Nat Prod Res; 2007 Jul; 21(9):782-6. PubMed ID: 17763101
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deoxyamphimedine, a pyridoacridine alkaloid, damages DNA via the production of reactive oxygen species.
    Marshall KM; Andjelic CD; Tasdemir D; Concepción GP; Ireland CM; Barrows LR
    Mar Drugs; 2009 May; 7(2):196-209. PubMed ID: 19597581
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sagitol D, a New Thiazole Containing Pyridoacridine Alkaloid from a Vietnamese Ascidian.
    Utkina NK
    Nat Prod Commun; 2015 Sep; 10(9):1547-8. PubMed ID: 26594755
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Influence of polyamine architecture on the transport and topoisomerase II inhibitory properties of polyamine DNA-intercalator conjugates.
    Wang L; Price HL; Juusola J; Kline M; Phanstiel O
    J Med Chem; 2001 Oct; 44(22):3682-91. PubMed ID: 11606133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding to DNA and cytotoxic evaluation of ascididemin, the major alkaloid from the Mediterranean ascidian Cystodytes dellechiajei.
    Bonnard I; Bontemps N; Lahmy S; Banaigs B; Combaut G; Francisco C; Colson P; Houssier C; Waring MJ; Bailly C
    Anticancer Drug Des; 1995 Jun; 10(4):333-46. PubMed ID: 7786398
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cycloshermilamine D, a new pyridoacridine from the marine tunicate cystodytes violatinctus.
    Koren-Goldshlager G; Aknin M; Kashman Y
    J Nat Prod; 2000 Jun; 63(6):830-1. PubMed ID: 10869211
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Three new pyridoacridine type alkaloids from a singaporean ascidian.
    Nilar N; Sidebottom PJ; Carté BK; Butler MS
    J Nat Prod; 2002 Aug; 65(8):1198-200. PubMed ID: 12193032
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemical and Pharmacological Prospection of the Ascidian
    Batista PJ; Nuzzo G; Gallo C; Carbone D; dell'Isola M; Affuso M; Barra G; Albiani F; Crocetta F; Virgili R; Mazzella V; Castiglia D; d'Ippolito G; Manzo E; Fontana A
    Mar Drugs; 2024 Jan; 22(2):. PubMed ID: 38393046
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Topoisomerase II-mediated DNA cleavage activity and irreversibility of cleavable complex formation induced by DNA intercalator with alkylating capability.
    Kong XB; Rubin L; Chen LI; Ciszewska G; Watanabe KA; Tong WP; Sirotnak FM; Chou TC
    Mol Pharmacol; 1992 Feb; 41(2):237-44. PubMed ID: 1311406
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Temporal variation in the production of four secondary metabolites in a colonial ascidian.
    López-Legentil S; Bontemps-Subielos N; Turon X; Banaigs B
    J Chem Ecol; 2006 Sep; 32(9):2079-84. PubMed ID: 16924427
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Marine pyridoacridine alkaloids and synthetic analogues as antitumor agents.
    Delfourne E; Bastide J
    Med Res Rev; 2003 Mar; 23(2):234-52. PubMed ID: 12500290
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay.
    Snyder RD; Arnone MR
    Mutat Res; 2002 Jun; 503(1-2):21-35. PubMed ID: 12052500
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.