BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

345 related articles for article (PubMed ID: 7529176)

  • 1. Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.
    Lukacs GL; Mohamed A; Kartner N; Chang XB; Riordan JR; Grinstein S
    EMBO J; 1994 Dec; 13(24):6076-86. PubMed ID: 7529176
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The common variant of cystic fibrosis transmembrane conductance regulator is recognized by hsp70 and degraded in a pre-Golgi nonlysosomal compartment.
    Yang Y; Janich S; Cohn JA; Wilson JM
    Proc Natl Acad Sci U S A; 1993 Oct; 90(20):9480-4. PubMed ID: 7692448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Delta F508 CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression.
    Okiyoneda T; Harada K; Takeya M; Yamahira K; Wada I; Shuto T; Suico MA; Hashimoto Y; Kai H
    Mol Biol Cell; 2004 Feb; 15(2):563-74. PubMed ID: 14595111
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant (delta F508) cystic fibrosis transmembrane conductance regulator Cl- channel is functional when retained in endoplasmic reticulum of mammalian cells.
    Pasyk EA; Foskett JK
    J Biol Chem; 1995 May; 270(21):12347-50. PubMed ID: 7539001
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Limited proteolysis as a probe for arrested conformational maturation of delta F508 CFTR.
    Zhang F; Kartner N; Lukacs GL
    Nat Struct Biol; 1998 Mar; 5(3):180-3. PubMed ID: 9501909
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.
    Haggie PM; Stanton BA; Verkman AS
    J Biol Chem; 2002 May; 277(19):16419-25. PubMed ID: 11877404
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins.
    Ward CL; Kopito RR
    J Biol Chem; 1994 Oct; 269(41):25710-8. PubMed ID: 7523390
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway.
    Bannykh SI; Bannykh GI; Fish KN; Moyer BD; Riordan JR; Balch WE
    Traffic; 2000 Nov; 1(11):852-70. PubMed ID: 11208075
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational and temperature-sensitive stability defects of the delta F508 cystic fibrosis transmembrane conductance regulator in post-endoplasmic reticulum compartments.
    Sharma M; Benharouga M; Hu W; Lukacs GL
    J Biol Chem; 2001 Mar; 276(12):8942-50. PubMed ID: 11124952
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator.
    Pind S; Riordan JR; Williams DB
    J Biol Chem; 1994 Apr; 269(17):12784-8. PubMed ID: 7513695
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator.
    Younger JM; Chen L; Ren HY; Rosser MF; Turnbull EL; Fan CY; Patterson C; Cyr DM
    Cell; 2006 Aug; 126(3):571-82. PubMed ID: 16901789
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein.
    Brown CR; Hong-Brown LQ; Biwersi J; Verkman AS; Welch WJ
    Cell Stress Chaperones; 1996 Jun; 1(2):117-25. PubMed ID: 9222597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTR delta F508.
    Paddon C; Loayza D; Vangelista L; Solari R; Michaelis S
    Mol Microbiol; 1996 Mar; 19(5):1007-17. PubMed ID: 8830258
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive.
    Denning GM; Anderson MP; Amara JF; Marshall J; Smith AE; Welsh MJ
    Nature; 1992 Aug; 358(6389):761-4. PubMed ID: 1380673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calnexin Delta 185-520 partially reverses the misprocessing of the Delta F508 cystic fibrosis transmembrane conductance regulator.
    Okiyoneda T; Wada I; Jono H; Shuto T; Yoshitake K; Nakano N; Nagayama S; Harada K; Isohama Y; Miyata T; Kai H
    FEBS Lett; 2002 Aug; 526(1-3):87-92. PubMed ID: 12208510
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.
    Sato S; Ward CL; Krouse ME; Wine JJ; Kopito RR
    J Biol Chem; 1996 Jan; 271(2):635-8. PubMed ID: 8557666
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro pharmacologic restoration of CFTR-mediated chloride transport with sodium 4-phenylbutyrate in cystic fibrosis epithelial cells containing delta F508-CFTR.
    Rubenstein RC; Egan ME; Zeitlin PL
    J Clin Invest; 1997 Nov; 100(10):2457-65. PubMed ID: 9366560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.
    Lukacs GL; Chang XB; Bear C; Kartner N; Mohamed A; Riordan JR; Grinstein S
    J Biol Chem; 1993 Oct; 268(29):21592-8. PubMed ID: 7691813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi.
    Farinha CM; Matos P; Amaral MD
    FEBS J; 2013 Sep; 280(18):4396-406. PubMed ID: 23773658
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers.
    LeSimple P; Liao J; Robert R; Gruenert DC; Hanrahan JW
    J Physiol; 2010 Apr; 588(Pt 8):1195-209. PubMed ID: 20156845
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.