BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 7535056)

  • 1. Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of Hoechst 33258 analogues.
    Gupta R; Wang H; Huang L; Lown JW
    Anticancer Drug Des; 1995 Jan; 10(1):25-41. PubMed ID: 7535056
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of distamycin and netropsin analogues.
    Xie G; Gupta R; Lown JW
    Anticancer Drug Des; 1995 Jul; 10(5):389-409. PubMed ID: 7639929
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequence-specific DNA alkylation of novel tallimustine derivatives.
    Marchini S; Cozzi P; Beria I; Geroni C; Capolongo L; D'Incalci M; Broggini M
    Anticancer Drug Des; 1998 Apr; 13(3):193-205. PubMed ID: 9595033
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
    Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
    Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus.
    Brooks N; Lee M; Wright SR; Woo S; Centioni S; Hartley JA
    Anticancer Drug Des; 1997 Oct; 12(7):591-606. PubMed ID: 9365504
    [TBL] [Abstract][Full Text] [Related]  

  • 7. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Heterogeneity in the actions of drugs that bind in the DNA minor groove.
    Albert FG; Eckdahl TT; Fitzgerald DJ; Anderson JN
    Biochemistry; 1999 Aug; 38(31):10135-46. PubMed ID: 10433722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation.
    Gupta R; Liu J; Xie G; Lown JW
    Anticancer Drug Des; 1996 Dec; 11(8):581-96. PubMed ID: 9022747
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cinnamoyl nitrogen mustard derivatives of pyrazole analogues of tallimustine modified at the amidino moiety: design, synthesis, molecular modeling and antitumor activity studies.
    Baraldi PG; Beria I; Cozzi P; Geroni C; Espinosa A; Gallo MA; Entrena A; Bingham JP; Hartley JA; Romagnoli R
    Bioorg Med Chem; 2004 Jul; 12(14):3911-21. PubMed ID: 15210158
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective DNA interaction of the novel distamycin derivative FCE 24517.
    Broggini M; Erba E; Ponti M; Ballinari D; Geroni C; Spreafico F; D'Incalci M
    Cancer Res; 1991 Jan; 51(1):199-204. PubMed ID: 1859575
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA alkylation by minor groove-binding N1-alkoxyalkyl-bis-benzimidazoles.
    Gupta R; Huang L; Wang H; Lown JW
    Anticancer Drug Des; 1995 Sep; 10(6):451-61. PubMed ID: 7575987
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis and biological evaluation of benzoic acid mustard derivatives of imidazole-containing and C-terminal carboxamide analogues of distamycin.
    Hartley JA; Preti CS; Wyatt MD; Lee M
    Drug Des Discov; 1995 Apr; 12(4):323-35. PubMed ID: 9040992
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
    Wyatt MD; Garbiras BJ; Haskell MK; Lee M; Souhami RL; Hartley JA
    Anticancer Drug Des; 1994 Dec; 9(6):511-25. PubMed ID: 7880376
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mono- and dysfunctional nitrogen mustard analogues of the DNA minor groove binder pibenzimol. Synthesis, cytotoxicity and interaction with DNA.
    Smaill JB; Fan JY; Papa PV; O'Connor CJ; Denny WA
    Anticancer Drug Des; 1998 Apr; 13(3):221-42. PubMed ID: 9595035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Enhanced DNA alkylation activities of Hoechst 33258 analogues designed for bioreductive activation.
    Guan LL; Zhao R; Lown JW
    Biochem Biophys Res Commun; 1997 Feb; 231(1):94-8. PubMed ID: 9070226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.
    Brooks N; McHugh PJ; Lee M; Hartley JA
    Anticancer Drug Des; 1999 Feb; 14(1):11-8. PubMed ID: 10363024
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and anti-tumor evaluation of novel symmetrical bis-benzimidazoles.
    Yang YH; Cheng MS; Wang QH; Nie H; Liao N; Wang J; Chen H
    Eur J Med Chem; 2009 Apr; 44(4):1808-12. PubMed ID: 18762358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and anti-tumour activity of the spatially-separated mustard bis-N,N'-[3-(N-(2-chloroethyl)-N-ethyl)amino-5-[N,N-dimethylamino)methy l)-aminophenyl]-1,4-benzenedicarboxamide, which alkylates DNA exclusively at adenines in the minor groove.
    Prakash AS; Valu KK; Wakelin LP; Woodgate PD; Denny WA
    Anticancer Drug Des; 1991 Jul; 6(3):195-206. PubMed ID: 1872947
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.