These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 7536929)

  • 1. Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans.
    Hara M; Han M
    Proc Natl Acad Sci U S A; 1995 Apr; 92(8):3333-7. PubMed ID: 7536929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
    Wu Y; Han M; Guan KL
    Genes Dev; 1995 Mar; 9(6):742-55. PubMed ID: 7729690
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation.
    Wu Y; Han M
    Genes Dev; 1994 Jan; 8(2):147-59. PubMed ID: 8299935
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of corneal inflammation by the topical use of Ras farnesyltransferase inhibitors: selective inhibition of macrophage localization.
    Sonoda K; Sakamoto T; Yoshikawa H; Ashizuka S; Ohshima Y; Kishihara K; Nomoto K; Ishibashi T; Inomata H
    Invest Ophthalmol Vis Sci; 1998 Nov; 39(12):2245-51. PubMed ID: 9804132
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanism of activation of the Caenorhabditis elegans ras homologue let-60 by a novel, temperature-sensitive, gain-of-function mutation.
    Eisenmann DM; Kim SK
    Genetics; 1997 Jun; 146(2):553-65. PubMed ID: 9178006
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Manumycin and gliotoxin derivative KT7595 block Ras farnesylation and cell growth but do not disturb lamin farnesylation and localization in human tumour cells.
    Nagase T; Kawata S; Tamura S; Matsuda Y; Inui Y; Yamasaki E; Ishiguro H; Ito T; Miyagawa J; Mitsui H; Yamamoto K; Kinoshita M; Matsuzawa Y
    Br J Cancer; 1997; 76(8):1001-10. PubMed ID: 9376258
    [TBL] [Abstract][Full Text] [Related]  

  • 7. sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.
    Singh N; Han M
    Genes Dev; 1995 Sep; 9(18):2251-65. PubMed ID: 7557379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of Ras prenylation: a signaling target for novel anti-cancer drug design.
    Lerner EC; Hamilton AD; Sebti SM
    Anticancer Drug Des; 1997 Jun; 12(4):229-38. PubMed ID: 9199657
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
    Kornfeld K; Guan KL; Horvitz HR
    Genes Dev; 1995 Mar; 9(6):756-68. PubMed ID: 7729691
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ras farnesyltransferase inhibition: a novel and safe approach for cancer chemotherapy.
    Nammi S; Lodagala DS
    Acta Pharmacol Sin; 2000 May; 21(5):396-404. PubMed ID: 11324435
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification and classification of genes that act antagonistically to let-60 Ras signaling in Caenorhabditis elegans vulval development.
    Ceol CJ; Stegmeier F; Harrison MM; Horvitz HR
    Genetics; 2006 Jun; 173(2):709-26. PubMed ID: 16624904
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LET-23-mediated signal transduction during Caenorhabditis elegans development.
    Sternberg PW; Lesa G; Lee J; Katz WS; Yoon C; Clandinin TR; Huang LS; Chamberlin HM; Jongeward G
    Mol Reprod Dev; 1995 Dec; 42(4):523-8. PubMed ID: 8607985
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ROS regulation of RAS and vulva development in Caenorhabditis elegans.
    Kramer-Drauberg M; Liu JL; Desjardins D; Wang Y; Branicky R; Hekimi S
    PLoS Genet; 2020 Jun; 16(6):e1008838. PubMed ID: 32544191
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Farnesyltransferase inhibitors reduce Ras activation and ameliorate acetaminophen-induced liver injury in mice.
    Saha B; Nandi D
    Hepatology; 2009 Nov; 50(5):1547-57. PubMed ID: 19739265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Manumycin inhibits cell proliferation and the Ras signal transduction pathway in human hepatocellular carcinoma cells.
    Zhou JM; Zhu XF; Pan QC; Liao DF; Li ZM; Liu ZC
    Int J Mol Med; 2003 Jun; 11(6):767-71. PubMed ID: 12736720
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Correlation between inhibitory effect of Manumycin on human hepatoma cancer cell HepG2 and Ras signal transduction pathway].
    Zhou JM; Pan QC; Yang XP; Liu ZC; Liao DF; Fu LW; Liang YJ
    Ai Zheng; 2002 Apr; 21(4):364-8. PubMed ID: 12452012
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?
    Cox AD; Der CJ
    Biochim Biophys Acta; 1997 Aug; 1333(1):F51-71. PubMed ID: 9294018
    [No Abstract]   [Full Text] [Related]  

  • 18. The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction.
    Sundaram M; Han M
    Cell; 1995 Dec; 83(6):889-901. PubMed ID: 8521513
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Farnesyltransferase inhibitors block the neurofibromatosis type I (NF1) malignant phenotype.
    Yan N; Ricca C; Fletcher J; Glover T; Seizinger BR; Manne V
    Cancer Res; 1995 Aug; 55(16):3569-75. PubMed ID: 7627966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Analysis of dominant-negative mutations of the Caenorhabditis elegans let-60 ras gene.
    Han M; Sternberg PW
    Genes Dev; 1991 Dec; 5(12A):2188-98. PubMed ID: 1748278
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.