These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
24. A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor. Hubbard CE; Barrios AM Bioorg Med Chem Lett; 2008 Jan; 18(2):679-81. PubMed ID: 18240386 [TBL] [Abstract][Full Text] [Related]
25. The difluoromethylenesulfonic acid group as a monoanionic phosphate surrogate for obtaining PTP1B inhibitors. Leung C; Grzyb J; Lee J; Meyer N; Hum G; Jia C; Liu S; Taylor SD Bioorg Med Chem; 2002 Jul; 10(7):2309-23. PubMed ID: 11983529 [TBL] [Abstract][Full Text] [Related]
26. Thiophosphate derivatives as inhibitors of tyrosine phosphatases. Zhao Z Biochem Biophys Res Commun; 1996 Jan; 218(2):480-4. PubMed ID: 8561781 [TBL] [Abstract][Full Text] [Related]
27. Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Jia Z; Barford D; Flint AJ; Tonks NK Science; 1995 Jun; 268(5218):1754-8. PubMed ID: 7540771 [TBL] [Abstract][Full Text] [Related]
28. An antiestrogen: a phosphotyrosyl peptide that blocks dimerization of the human estrogen receptor. Arnold SF; Notides AC Proc Natl Acad Sci U S A; 1995 Aug; 92(16):7475-9. PubMed ID: 7543683 [TBL] [Abstract][Full Text] [Related]
29. High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide. Phan J; Lee K; Cherry S; Tropea JE; Burke TR; Waugh DS Biochemistry; 2003 Nov; 42(45):13113-21. PubMed ID: 14609321 [TBL] [Abstract][Full Text] [Related]
30. Structure-based design and discovery of protein tyrosine phosphatase inhibitors incorporating novel isothiazolidinone heterocyclic phosphotyrosine mimetics. Combs AP; Yue EW; Bower M; Ala PJ; Wayland B; Douty B; Takvorian A; Polam P; Wasserman Z; Zhu W; Crawley ML; Pruitt J; Sparks R; Glass B; Modi D; McLaughlin E; Bostrom L; Li M; Galya L; Blom K; Hillman M; Gonneville L; Reid BG; Wei M; Becker-Pasha M; Klabe R; Huber R; Li Y; Hollis G; Burn TC; Wynn R; Liu P; Metcalf B J Med Chem; 2005 Oct; 48(21):6544-8. PubMed ID: 16220970 [TBL] [Abstract][Full Text] [Related]
31. Flag-insulin receptor mutants. Goren HJ Ann N Y Acad Sci; 1995 Sep; 766():463-5. PubMed ID: 7486692 [No Abstract] [Full Text] [Related]
32. A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors. Tulsi NS; Downey AM; Cairo CW Bioorg Med Chem; 2010 Dec; 18(24):8679-86. PubMed ID: 21055952 [TBL] [Abstract][Full Text] [Related]
33. The crystal structures of the SH2 domain of p56lck complexed with two phosphonopeptides suggest a gated peptide binding site. Mikol V; Baumann G; Keller TH; Manning U; Zurini MG J Mol Biol; 1995 Feb; 246(2):344-55. PubMed ID: 7532720 [TBL] [Abstract][Full Text] [Related]
34. Synthetic Tyr-phospho and non-hydrolyzable phosphonopeptides as PTKs and TC-PTP inhibitors. Ruzza P; Deana AD; Calderan A; Pavanetto M; Cesaro L; Pinna LA; Borin G Int J Pept Protein Res; 1995 Dec; 46(6):535-46. PubMed ID: 8748714 [TBL] [Abstract][Full Text] [Related]
35. Insulin-induced tyrosine dephosphorylation of paxillin and focal adhesion kinase requires active phosphotyrosine phosphatase 1D. Ouwens DM; Mikkers HM; van der Zon GC; Stein-Gerlach M; Ullrich A; Maassen JA Biochem J; 1996 Sep; 318 ( Pt 2)(Pt 2):609-14. PubMed ID: 8809054 [TBL] [Abstract][Full Text] [Related]
36. Continuous spectrophotometric assay of protein tyrosine phosphatase using phosphotyrosine. Zhao Z; Zander NF; Malencik DA; Anderson SR; Fischer EH Anal Biochem; 1992 May; 202(2):361-6. PubMed ID: 1381565 [TBL] [Abstract][Full Text] [Related]
37. Utilization of 3'-carboxy-containing tyrosine derivatives as a new class of phosphotyrosyl mimetics in the preparation of novel non-phosphorylated cyclic peptide inhibitors of the Grb2-SH2 domain. Song YL; Tan J; Luo XM; Long YQ Org Biomol Chem; 2006 Feb; 4(4):659-66. PubMed ID: 16467940 [TBL] [Abstract][Full Text] [Related]
38. In silico structure-based design of a potent and selective small peptide inhibitor of protein tyrosine phosphatase 1B, a novel therapeutic target for obesity and type 2 diabetes mellitus: a computer modeling approach. Rao GS; Ramachandran MV; Bajaj JS J Biomol Struct Dyn; 2006 Feb; 23(4):377-84. PubMed ID: 16363874 [TBL] [Abstract][Full Text] [Related]
39. Discovery of a novel nonphosphorylated pentapeptide motif displaying high affinity for Grb2-SH2 domain by the utilization of 3'-substituted tyrosine derivatives. Song YL; Peach ML; Roller PP; Qiu S; Wang S; Long YQ J Med Chem; 2006 Mar; 49(5):1585-96. PubMed ID: 16509576 [TBL] [Abstract][Full Text] [Related]
40. Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands. Yao ZJ; King CR; Cao T; Kelley J; Milne GW; Voigt JH; Burke TR J Med Chem; 1999 Jan; 42(1):25-35. PubMed ID: 9888830 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]