BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 7538194)

  • 1. Residue 78 in the second transmembrane domain of the neurokinin-1 receptor is important in coupling high affinity agonist binding to multiple second messenger responses.
    Brodbeck RM; Sachais BS; Krause JE
    Mol Pharmacol; 1995 May; 47(5):1065-71. PubMed ID: 7538194
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An arginine residue conserved in most G protein-coupled receptors is essential for the function of the m1 muscarinic receptor.
    Zhu SZ; Wang SZ; Hu J; el-Fakahany EE
    Mol Pharmacol; 1994 Mar; 45(3):517-23. PubMed ID: 8145736
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors.
    Lee NH; Geoghagen NS; Cheng E; Cline RT; Fraser CM
    Mol Pharmacol; 1996 Jul; 50(1):140-8. PubMed ID: 8700106
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association.
    Kong H; Raynor K; Yasuda K; Bell GI; Reisine T
    Mol Pharmacol; 1993 Aug; 44(2):380-4. PubMed ID: 8102784
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Point mutation increases a form of the NK1 receptor with high affinity for neurokinin A and B and septide.
    Ciucci A; Palma C; Manzini S; Werge TM
    Br J Pharmacol; 1998 Sep; 125(2):393-401. PubMed ID: 9786514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Internalization of the gastrin-releasing peptide receptor is mediated by both phospholipase C-dependent and -independent processes.
    Benya RV; Akeson M; Mrozinski J; Jensen RT; Battey JF
    Mol Pharmacol; 1994 Sep; 46(3):495-501. PubMed ID: 7935330
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An aspartate residue at the extracellular boundary of TMII and an arginine residue in TMVII of the gastrin-releasing peptide receptor interact to facilitate heterotrimeric G protein coupling.
    Donohue PJ; Sainz E; Akeson M; Kroog GS; Mantey SA; Battey JF; Jensen RT; Northup JK
    Biochemistry; 1999 Jul; 38(29):9366-72. PubMed ID: 10413511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Binding sites and transduction process of the cholecystokininB receptor: involvement of highly conserved aromatic residues of the transmembrane domains evidenced by site-directed mutagenesis.
    Jagerschmidt A; Guillaume N; Roques BP; Noble F
    Mol Pharmacol; 1998 May; 53(5):878-85. PubMed ID: 9584214
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of the COOH-terminal domain of the neurotensin receptor with a G protein does not control the phospholipase C activation but is involved in the agonist-induced internalization.
    Hermans E; Octave JN; Maloteaux JM
    Mol Pharmacol; 1996 Feb; 49(2):365-72. PubMed ID: 8632771
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential involvement of intracellular domains of the rat NTS1 neurotensin receptor in coupling to G proteins: a molecular basis for agonist-directed trafficking of receptor stimulus.
    Skrzydelski D; Lhiaubet AM; Lebeau A; Forgez P; Yamada M; Hermans E; Rostene W; Pelaprat D
    Mol Pharmacol; 2003 Aug; 64(2):421-9. PubMed ID: 12869647
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The ligand binding site of the formyl peptide receptor maps in the transmembrane region.
    Miettinen HM; Mills JS; Gripentrog JM; Dratz EA; Granger BL; Jesaitis AJ
    J Immunol; 1997 Oct; 159(8):4045-54. PubMed ID: 9378994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutational analysis of the potential phosphorylation sites for protein kinase C on the CCK(A) receptor.
    Smeets RL; Fouraux MA; Pouwels W; van Emst-de Vries SE; Ronken E; De Pont JJ; Willems PH
    Br J Pharmacol; 1998 Jul; 124(5):935-45. PubMed ID: 9692779
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Activation of heterologously expressed D3 dopamine receptors: comparison with D2 dopamine receptors.
    Chio CL; Lajiness ME; Huff RM
    Mol Pharmacol; 1994 Jan; 45(1):51-60. PubMed ID: 8302280
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular cloning, functional characterization, and chromosomal localization of a human somatostatin receptor (somatostatin receptor type 5) with preferential affinity for somatostatin-28.
    Panetta R; Greenwood MT; Warszynska A; Demchyshyn LL; Day R; Niznik HB; Srikant CB; Patel YC
    Mol Pharmacol; 1994 Mar; 45(3):417-27. PubMed ID: 7908405
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor.
    Cascieri MA; Ber E; Fong TM; Sadowski S; Bansal A; Swain C; Seward E; Frances B; Burns D; Strader CD
    Mol Pharmacol; 1992 Sep; 42(3):458-63. PubMed ID: 1383685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutation of a highly conserved aspartate residue in the second transmembrane domain of the cannabinoid receptors, CB1 and CB2, disrupts G-protein coupling.
    Tao Q; Abood ME
    J Pharmacol Exp Ther; 1998 May; 285(2):651-8. PubMed ID: 9580609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors.
    Cascieri MA; Huang RR; Fong TM; Cheung AH; Sadowski S; Ber E; Strader CD
    Mol Pharmacol; 1992 Jun; 41(6):1096-9. PubMed ID: 1377326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Selective coupling of prostaglandin E receptor EP3D to multiple G proteins depending on interaction of the carboxylic acid of agonist and arginine residue of seventh transmembrane domain.
    Negishi M; Harazono A; Sugimoto Y; Hazato A; Kurozumi S; Ichikawa A
    Biochem Biophys Res Commun; 1995 Jul; 212(2):279-85. PubMed ID: 7626039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single amino acid substitutions in the pm2 muscarinic receptor alter receptor/G protein coupling without changing physiological responses.
    Bulseco DA; Schimerlik MI
    Mol Pharmacol; 1996 Jan; 49(1):132-41. PubMed ID: 8569698
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rat somatostatin receptor type 1 couples to G proteins and inhibition of cyclic AMP accumulation.
    Hadcock JR; Strnad J; Eppler CM
    Mol Pharmacol; 1994 Mar; 45(3):410-6. PubMed ID: 8145728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.