BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 7538902)

  • 1. Mutant p53 rescues human diploid cells from senescence without inhibiting the induction of SDI1/WAF1.
    Bond JA; Blaydes JP; Rowson J; Haughton MF; Smith JR; Wynford-Thomas D; Wyllie FS
    Cancer Res; 1995 Jun; 55(11):2404-9. PubMed ID: 7538902
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Polyamine depletion in human melanoma cells leads to G1 arrest associated with induction of p21WAF1/CIP1/SDI1, changes in the expression of p21-regulated genes, and a senescence-like phenotype.
    Kramer DL; Chang BD; Chen Y; Diegelman P; Alm K; Black AR; Roninson IB; Porter CW
    Cancer Res; 2001 Nov; 61(21):7754-62. PubMed ID: 11691789
    [TBL] [Abstract][Full Text] [Related]  

  • 3. S phase cell-cycle arrest following DNA damage is independent of the p53/p21(WAF1) signalling pathway.
    Wyllie FS; Haughton MF; Bond JA; Rowson JM; Jones CJ; Wynford-Thomas D
    Oncogene; 1996 Mar; 12(5):1077-82. PubMed ID: 8649799
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53.
    Fang L; Igarashi M; Leung J; Sugrue MM; Lee SW; Aaronson SA
    Oncogene; 1999 May; 18(18):2789-97. PubMed ID: 10362249
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53-dependent signaling sustains DNA replication and enhances clonogenic survival in 254 nm ultraviolet-irradiated human fibroblasts.
    Cistulli CA; Kaufmann WK
    Cancer Res; 1998 May; 58(9):1993-2002. PubMed ID: 9581844
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.
    el-Deiry WS; Harper JW; O'Connor PM; Velculescu VE; Canman CE; Jackman J; Pietenpol JA; Burrell M; Hill DE; Wang Y
    Cancer Res; 1994 Mar; 54(5):1169-74. PubMed ID: 8118801
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.
    Huang S; Liu LN; Hosoi H; Dilling MB; Shikata T; Houghton PJ
    Cancer Res; 2001 Apr; 61(8):3373-81. PubMed ID: 11309295
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 checkpoint-defective cells are sensitive to X rays, but not hypoxia.
    Denko NC; Green SL; Edwards D; Giaccia AJ
    Exp Cell Res; 2000 Jul; 258(1):82-91. PubMed ID: 10912790
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Induction of apoptosis by the p53-273L (Arg --> Leu) mutant in HSC3 cells without transactivation of p21Waf1/Cip1/Sdi1 and bax.
    Kaneuchi M; Yamashita T; Shindoh M; Segawa K; Takahashi S; Furuta I; Fujimoto S; Fujinaga K
    Mol Carcinog; 1999 Sep; 26(1):44-52. PubMed ID: 10487521
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53-mediated accumulation of hypophosphorylated pRb after the G1 restriction point fails to halt cell cycle progression.
    Linke SP; Harris MP; Neugebauer SE; Clarkin KC; Shepard HM; Maneval DC; Wahl GM
    Oncogene; 1997 Jul; 15(3):337-45. PubMed ID: 9233768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanisms of regulation of WAF1/Cip1 gene expression in human breast carcinoma: role of p53-dependent and independent signal transduction pathways.
    Sheikh MS; Li XS; Chen JC; Shao ZM; Ordonez JV; Fontana JA
    Oncogene; 1994 Dec; 9(12):3407-15. PubMed ID: 7970699
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Aberrant p21WAF1-dependent growth arrest as the possible mechanism of abnormal resistance to ultraviolet light cytotoxicity in Li-Fraumeni syndrome fibroblast strains heterozygous for TP53 mutations.
    Barley RD; Enns L; Paterson MC; Mirzayans R
    Oncogene; 1998 Aug; 17(5):533-43. PubMed ID: 9704919
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Cell cycle regulation after exposure to ionizing radiation].
    Teyssier F; Bay JO; Dionet C; Verrelle P
    Bull Cancer; 1999 Apr; 86(4):345-57. PubMed ID: 10341340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regeneration.
    Albrecht JH; Meyer AH; Hu MY
    Hepatology; 1997 Mar; 25(3):557-63. PubMed ID: 9049198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct p53-mediated G1/S checkpoint responses in two NIH3T3 subclone cells following treatment with DNA-damaging agents.
    Huang TS; Kuo ML; Shew JY; Chou YW; Yang WK
    Oncogene; 1996 Aug; 13(3):625-32. PubMed ID: 8760304
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Wild-type p53 can induce p21 and apoptosis in neuroblastoma cells but the DNA damage-induced G1 checkpoint function is attenuated.
    McKenzie PP; Guichard SM; Middlemas DS; Ashmun RA; Danks MK; Harris LC
    Clin Cancer Res; 1999 Dec; 5(12):4199-207. PubMed ID: 10632361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. p53-independent induction of WAF1/CIP1 in human leukemia cells is correlated with growth arrest accompanying monocyte/macrophage differentiation.
    Zhang W; Grasso L; McClain CD; Gambel AM; Cha Y; Travali S; Deisseroth AB; Mercer WE
    Cancer Res; 1995 Feb; 55(3):668-74. PubMed ID: 7834638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis.
    Chen X; Bargonetti J; Prives C
    Cancer Res; 1995 Oct; 55(19):4257-63. PubMed ID: 7671232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Perifosine, a novel alkylphospholipid, induces p21(WAF1) expression in squamous carcinoma cells through a p53-independent pathway, leading to loss in cyclin-dependent kinase activity and cell cycle arrest.
    Patel V; Lahusen T; Sy T; Sausville EA; Gutkind JS; Senderowicz AM
    Cancer Res; 2002 Mar; 62(5):1401-9. PubMed ID: 11888912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1.
    Cox LS
    J Pathol; 1997 Oct; 183(2):134-40. PubMed ID: 9390024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.